Home  |  Contact Us  |  Sitemap
 

 
  NEW DRUGS
Centchroman
Centbucridine
Arteether
Bulaquin
Gugulipid
Standardised Herbal Remedy
Isaptent
Centpropazine
Consap
Picroliv
CDRI-99/373
 
  NEW DIAGNOSTICS
Diagnostic Vaccine
Cholera Vaccine
 
  NEW TECHNOLOGY
 
  Other Links
New Facilities
CDRI Publications
Library Holding
Directory
C D R I Tenders
Admin Login
  PICROLIV
 
Click for +zoom
Picroliv
...  
Picroliv is a hepatoprotective agent of plant origin. It is an iridoid glycoside mixture containing 60% picroside I and kutoside in the ratio of 1:1.5 obtained from the plant, Picrorhiza kurrooa ( root and rhizome ). Picroliv ( 6 and 12.5 mg/ kg ) has shown efficacy comparable to silymarin ( 10 and 20 mg/ kg ) in rodent models of galactosamine, paracetamol, thioacetamide and CC14 induced hepatic damage. Picroliv has shown cholerectic effect in rat and anti-cholestatic effect in rat, guinea pigs and cats treated with paracetamol and ethinyl estradiol. It has also antiviral and immunostimulant activities. Picroliv is devoid of any significant CNS and CVS , autonomic and other systemic activity.

Picroliv appears to be safe in rats and monkeys and has excellent therapeutic index. Phase I and II clinical trials have been conducted and the drug has shown no side effect and is well tolerated.

 

 
 
 
 
website copyright © Central Drug Research Institute. All rights reserved.
No part of this should be Downloaded or used in any way other than the non-commercial purposes without prior permission of the Director, CDRI.
Powered by MARG Software Solutions | Contact us
You are Visitor No.
Best viewed at 800 X 600 Resolutions | Internet Explorer 5.0 - Later Version <% if session("iNumber")="" then 'conn.open mydsn Dim rsHits Set rsHits=Server.CreateObject("ADODB.Recordset") rsHits.CursorLocation=adUseClient rsHits.Open "Select visits from Hits", conn, adOpenKeyset, adLockOptimistic session("iNumber")=rsHits("visits") + 1 rsHits("visits")=rsHits("visits") + 1 rsHits.Update rsHits.Close set rsHits=Nothing end if If Len(session("iNumber")) > 0 then 'Display iNumber Response.Write "
" & ConstructDigits(session("iNumber")) & "
" End If '''' Function ConstructDigits(iValue) 'This function accepts a single parameter, iValue, and 'returns HTML containing a series of images representing 'a graphical image of the value in iValue 'Start by ensuring iValue is a number If Not IsNumeric(iValue) then ConstructDigits = iValue & " IS NOT A NUMBER!" Exit Function End If 'Can't show decimals! If InStr(1, iValue, ".") then ConstructDigits = "CANNOT CONTAIN DECIMALS!" Exit Function End If 'Can't show negative numbers! If iValue < 0 then ConstructDigits = "CANNOT DISPLAY NEGATIVE NUMBERS!" Exit Function End If Dim iLoop, strResults For iLoop = (Len(iValue) - 1) to 0 STEP -1 strResults = strResults & "" Next ConstructDigits = strResults End Function '''' %>