Dr. VISHNU LAL SHARMA
 




Scientist F
Medicinal & Process Chemistry Division
Central Drug Research Institute,
Lucknow- 226001
 
Educational Qualifications M.Sc., Ph.D.
Date of Birth 07-02-1958
E- Mail vlscdri@rediffmail.com
 
 POST-DOCTORAL RESEARCH
 
•
 University of Duesseldorf, Duesseldorf (Germany) from Oct.1994 to Dec.1994
 
RESEARCH EXPERIENCE
 
•
 Synthetic Organic Chemistry (28 years)
 
CURRENT AREAS OF INTEREST
 
•
 Medicinal Organic Chemistry
 
SELECTED PUBLICATIONS ( Total Publications - Research Papers: 44, Patents: 2)
 
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 Nand Lal, Lalit Kumar, Amit Sarswat, Santosh Jangir and Vishnu Lal Sharma, “Synthesis of S-(2-thioxo-1,3-dithiolan-4-yl)methyl-dialkylcarbamothioate and S-thiiran-2-ylmethyl-dialkylcarbamothioate via Intermolecular O-S Rearrangement in Water” Organic Letters, 2011, 13(9), 2330-2333.
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 Amit Sarswat, Rajeev Kumar, Lalit Kumar, Nand Lal, Smiriti Sharma, Yenamandra S. Prabhakar, Shailendra K. Pandey, Jawahar Lal, Vikas Verma, Ashish Jain, Jagdamba P. Maikhuri, Diwakar Dalela, Kirti, Gopal Gupta, Vishnu L. Sharma, “Arylpiperazines for Management of Benign Prostatic Hyperplasia: Design, Synthesis, Quantative Structure - Activity Relationships, and Parmacokinetic Studies” J. Med. Chem., 2011, 54 (1), 302-311.
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 Lalit Kumar, Amit Sarswat, Nand Lal, Ashish Jain, Sumit Kumar, S.T.V.S. Kiran Kumar, Jagdamba P. Maikhuri, Atindra K. Pandey, Praveen K. Shukla, Gopal Gupta, Vishnu L. Sharma “ Design and Synthesis of 3-(azol-1-yl)phenylprapanes as spermicide for prophylactic contraception ” Bioorg. Med. Chem. Lett., 2011, 21(1), 176-181.
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 Rajiv K. Jain, Ashish Jain, Rajeev Kumar, Vikas Verma, Jagdamba P. Maikhuri, Vishnu L. Sharma, Kalyan Maitra, Sanjay Batra, Gopal Gupta, “ Functional attenuation of human sperm by novel, non-surfactant spermicides: precise targeting of membrane physiology without affecting structure ” Human Reproduction, 2010, 25,1165-1176.
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 Lalit Kumar, Amit Sarswat, Nand Lal, Vishnu L. Sharma, Ashish Jain, Rajeev Kumar, Vikas Verma, Jagdamba P. Maikhuri, Awanit Kumar, Praveen K. Shukla, and Gopal Gupta, “Imidazole derivatives as possible microbicides with dual protection” European J. Med.Chem., 2010, 45(2), 817-824.
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 Rajiv K. Jain, Ashish Jain, Jagdamba P. Maikhuri, Vishnu L. Sharma, S.T.V.S. Kiran Kumar Anil K.Dwivedi, Kalyan Maitra, Virendra K. Bajpai and Gopal Gupta, “In vitro testing of rationally designed spermicides for selectively targeting human sperm in vagina to ensure safe contraception” Human Reproduction, 2009, 24,590-601.
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 V. S. Kiran Kumar Srimath Tirumala, Lalit Kumar, Vishnu L. Sharma, Ashish Jain, Rajeev K. Jain, Jagdamba P. Maikhuri, Manish Kumar, Praveen K. Shukla, and Gopal Gupta, “Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides” European J. Med.Chem., 2008, 43(10), 2247-2256.
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 Anil Kumar Dwivedi , Vishnu Lal Sharma, Niharika Kumaria, S. T. V. S. Kiran Kumar, Pradeep Kumar Srivastava., Abdul Haq Ansari,. Jagdamba Prasad Maikhuri , Gopal Gupta, Janak Dulari Dhar, Raja Roy, Bhawani Shankar Joshi, Praveen Kumar Shukla , Manish Kumar, and Satyawan Singh, “Synthesis of disulfide esters of dialkylaminocarbothioic acid as potential spermicidal agents” Bioorg. Med.Chem., 2007, 15(21), 6642-6648.
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 V.S. Kiran Kumar S.T., Vishnu Lal Sharma, Pratibha Tiwari, Divya Singh, Jagdamba Prasad Maikhuri, Gopal Gupta & Man Mohan Singh, “ The spermicidal and antitrichomonas activity of SSRI antidepressants” Bioorg. Med. Chem. Lett., 2006, 16(9), 2509-12.
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 S.T.V.S. Kiran Kumar, V.L.Sharma & A.K.Dwivedi, “A simple and convenient method for the synthesis of 1-dialkylaminocarbothioic acid S-[(2,3- epithio)propyl] esters” J. Het. Chem., 2006, 43 (1), 001-005.
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 S.T.V.S. Kiran Kumar, Vishnu Lal Sharma, Manish Kumar, Praveen Kumar Shukla, Pratibha Tiwari, Rajeev Kumar Jain, Jagdamba Prasad Maikhuri, Divya Singh, Gopal Gupta, and Man Mohan Singh,
“Synthesis of Benzenepropanamine analogues as non-detergent spermicides with antitrichomonas and anticandida activities” Bioorg. Med. Chem., 2006, 14(19), 6593-6600.
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 R.K. Jain, J.P. Maikhuri, S.T.V.S. Kiran Kumar, V.L.Sharma, A.K.Dwivedi, K. Maitra, V.K. Bajpai and G. Gupta, “ Novel disulfide esters of carbothioic acid as potent, non-detergent spermicides with low toxicity to Lactobacillus and Hela cells in vitro” Human Reproduction, 2006, 22,708-716.
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 Anita Mukherjee, Mohammed S. Akhtar, Vishnu L. Sharma, Manju Seth, Amiya P. Bhaduri, Anila Agnihotri, Puroshottam K. Mehrotra and Ved Prakash Kamboj, “Synthesis and Bioevaluation of ubstituted Dihydropyridines for Pregnancy- Interceptive Activity in Hamsters”. J. Med. Chem., 1989, 32, 2297-300.