DR. ATUL GOEL
 
...

Medicinal and Process Chemistry Division
Central Drug Research Institute
Lucknow 226001, India
Tel.: 2212411-18 Extn. 4381
 
Educational qualifications M.Sc., Ph.D.

Date of Birth 13th March, 1970
E Mail agoel13@yahoo.com
 
POSTDOCTORAL RESEARCH
  National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA during May 1999 - Oct. 2001.
 
RESEARCH EXPERIENCE
  Organic and Medicinal Chemistry (10 years)
 
CURRENT AREAS OF INTEREST
  Development of innovative routes of biologically important entities through ring transformation reactions, Development of new antihyperglycemic agents, Application of Molecular Modeling in drug research
 
HONOURS & AWARD
  Ramanna Fellowship in 2007 by Department of Science and Technology, New Delhi
  Young Scientist Award-2005 for significant contribution in Science and Technology by Government of Uttar Pradesh, India
RESEARCH GROUP
  1. Dr. Fateh Veer Singh (Currently in Brazil)
2. Dr. Manish Dixit (Currently in USA)
3. Ms. Deepti Verma (SRF)
4. Mr. Sumit Chaurasia (SRF)
5. Mr. Amit Kumar (SRF)
6. Mr. Vijay Kumar (JRF)
7. Mr. Salil pratap Singh (JRF)
 
SELECTED PUBLICATIONS
 
•
 Goel, A., Singh, F. V., Dixit, M., Verma, D., Raghunandan, R., Maulik, P. R. (2007): Highly efficient non-palladium-catalyzed controlled synthesis and X-ray analysis of functionalized 1,2-diaryl-, 1,2,3-Triaryl- and 1,2,3,4-Tetraarylbenzenes. Chem Asian J. 2, 239-247.
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 Goel, A., Singh, F. V., Kumar, V., Reichert, M., Gulder, T. A. M., Bringmann, G. (2007): Synthesis, Optical Resolution, and Configurational Assignment of Novel Axially Chiral Quateraryls. J. Org. Chem. 72, 7765-7768.
•
 Dixit, M., Raghunandan, R., Kumar, B., Maulik, P. R., Goel, A. (2007): One-pot Regioselective Synthesis of Nature Mimicking Dihydronaphthofurans and Dibenzofurans. Tetrahedron 63, 1610.
•
 Pratap, R., Kushwaha, S. P., Goel, A., Ram, V. J. (2007): An efficient synthesis of (E)-(2-arylpyrazino[1,2-a]pyrimidine-4-ylidene)acetonitriles and cyanomethyl appended pyrimidines. Tetrahedron Lett. 48, 549-553.
•
 Dixit, M., Tripathi, B. K., Tamrakar, A. K., Srivastava, A. K., Kumar, B., Goel, A. (2007): Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors. Bioorg. Med. Chem. 15, 727-734.
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 Singh, F. V., Joshi, M. D., Srivastava, A. K., Goel, A. (2007): Synthesis and In Vivo Antihyperglycaemic Activity of Nature Mimicking Furanyl-2-pyranones in STZ-S Model. Bioorg. Med. Chem. Lett. 17, 2425
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 Pratap, R., Roy, A. D., Kushwaha, S. P., Goel, A., Roy, R., Ram, V. J. (2007): Guanidine and amidine mediated synthesis of bridgehead triazaphenalenes, pyrimidines and pyridines through domino reactions. Tetrahedron Lett. 48, 5845-5849
•
 Singh, F. V., Kumar, V., Goel, A. (2007): Regioselective Synthesis of Functionally Crowded Benzenes at Room Temperature through Ring Transformation of 2H-Pyran-2-ones. Synlett, 2086-2090
•
 Goel, A., Singh, F. V., Kumar, A. (2007): A Regioselective Palladium-Free Protocol for Accessing Unsymmetrical Biaryls through Ring Transformation of 6-Aryl-?-pyrones. Tetrahedron Lett, 48, 7283-7286
•
 Singh, F. V., Kumar, V., Kumar, B., Goel, A. (2007): Regioselective Synthesis of 2-Amino-isophthalonitriles through Ring Transformation Strategy. Tetrahedron, 63, 10971
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 Dixit, M., Saeed, U., Kumar, A., Siddiqi, M. I., Tamrakar, A. K., Srivastava, A. K., Goel, A. (2007): Synthesis, Molecular Docking and PTP1B Inhibitory Activity of Functionalized 4,5-Dihydronaphthofurans and Dibenzofurans. Medicinal Chemsitry, in press
•
 Kumar, A,. Singh, F. V., Goel, A. (2007): Regioselective Synthesis of Functionally Hindered ?-Methylstyrenes through Ring transformation of 2H-Pyran-2-ones with Mesityl Oxide. Tetrahedron Lett., In press.
•
 Singh, F. V., Dixit, M., Chaurasia, S., Raghunandan, R., Maulik, P. R., Goel, A. (2007): Substituent-Controlled General Approach to Access Arylated Pyran-2-ones and Pyrano[3,4-c]pyran-1,8-diones. Tetrahedron Lett., Accepted.