AAMIR NAZIR
 
.. Scientist C
Toxicology Division
Central Drug Research Institute,
Lucknow-226 001
 
Educational Qualifications M.Sc., Ph.D. (Toxicology)
Phone +91-522-2612411-18 Ext. 4274
Fax +91-522-2623405
E-Mail anazir[at]cdri.res.in
Date of Birth 09.01.1974
 
POST DOCTORAL RESEARCH EXPERIENCE
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 Carried out research work at Medical College of Georgia, USA.
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 Studied mechanism of anesthetic drug action employing RNAi induced gene silencing in genetic model system Caenorhabditis elegans.
 
CURRENT AREAS OF INTEREST
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 Functional genomics approaches employing model system Caenorhabditis elegans in toxicity studies and towards identification of novel drug targets. Click for his lab's details
 
GROUP MEMBERS
Shreesh Raj Sammi, SRF, CSIR
Pooja Jadiya, Project Assistant II, CSIR
Supinder Kaur, Project Assistant II, DST
 
SELECTED PUBLICATIONS
 
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 Pooja Jadiya, Manavi Chatterjee, Shreesh Raj Sammi, Supinder Kaur, Gautam Palit, Aamir Nazir (2011) Sir-2.1 modulates ‘calorie-restriction-mediated’ prevention of neurodegeneration in Caenorhabditis elegans: Implications for Parkinson’s disease. Biochem. Biophys. Res. Commun. (2011), 413(2), 306-310.
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Pooja Jadiya, Asif Khan, Shreesh Raj Sammi, Supinder Kaur, Snober S. Mir, Aamir Nazir. (2011) Anti-Parkinsonian effects of Bacopa monnieri: Insights from transgenic and pharmacological Caenorhabditis elegans models of Parkinson’s disease. Biochem. Biophys. Res. Commun. 413(4), 605-610.
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 Aamir Nazir, Shreesh Raj Sammi, Pankaj Singh and Raj Kamal Tripathi (2010) Trans-cellular Introduction of HIV-1 Protein Nef Induces Pathogenic Response in Caenorhabditis elegans. PLoS ONEDec. 13; 5(12): e15312.
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 Shailendra S. Chaudhaery, Kuldeep K. Roy, Neeraj Shakya, Gunjan Saxena, Shreesh Raj Sammi, Aamir Nazir, Chandishwar Nath and Anil K. Saxena (2010) Novel Carbamates as Orally Active Acetylcholinesterase Inhibitors Found to Improve Scopolamine-Induced Cognition Impairment: Pharmacophore-Based Virtual Screening, Synthesis, and Pharmacology. J. Med. Chem. 53(17): 6490-6505.
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 Aamir Nazir, I. Mukhopadhyay, D. K. Saxena and D. Kar Chowdhuri (2006) Hsp70 expression in Drosophila melanogaster: Toxicological perspective in A.S.Sreedhar and U.K.Srinivas (Ed.) Stress Response: A Molecular Biology Approach. Research Signpost, India. pp. 207-226.
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 Aamir Nazir, D. K. Saxena and D. Kar Chowdhuri (2003) Induction of hsp70 in transgenic Drosophila: Biomarker of exposure against phthalimide group of chemicals. Biochim. Biophys. Acta. Vol. 1621(2): 218-225.
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 Aamir Nazir, I. Mukhopadhyay, D. K. Saxena and D. Kar Chowdhuri (2003) Evaluation of toxic potential of Captan: Induction of hsp70 and tissue damage in transgenic Drosophila melanogaster (hsp70-lacZ) Bg9 J. Biochem. Mol. Toxicol. Vol. 17(2): 98-107.
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 Aamir Nazir, I. Mukhopadhyay, D. K. Saxena and D. Kar Chowdhuri (2003) Evaluation of No Observed Adverse Effect level (NOAEL) of solvent Dimethyl Sulfoxide in Drosophila melanogaster. Toxicol. Mechanisms and Methods. 13(2): 147-152.
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 I. Mukhopadhyay, Aamir Nazir, D. K. Saxena and D. Kar Chowdhuri (2003) Heat shock response: hsp70 in environmental monitoring. J. Biochem. Mol. Toxicol. Vol. 17(5): 249-254.
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 I. Mukhopadhyay, Aamir Nazir, K. Mahmood, M. Das, D. K. Saxena, S. K. Khanna and D. Kar Chowdhuri (2002) Toxicity of argemone oil: Effect on hsp70 expression and tissue damage in transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. Cell Biol. Toxicol. Vol. 18: 1-11.
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 I. Mukhopadhyay, Aamir Nazir, D. K. Saxena and D. Kar Chowdhuri (2002) Toxicity of Cypermethrin: hsp70 as a biomarker of response in transgenic Drosophila. Biomarkers Vol. 7(6): 501-510.
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 Aamir Nazir, I. Mukhopadhyay, D. K. Saxena and D. Kar Chowdhuri (2001) Chlorpyrifos induced hsp70 expression and effect on reproductive performance in transgenic Drosophila melanogaster (hsp70-lacZ). Arch. Environ. Contam. Toxicol. Vol. 41: 443-449.
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 D. Kar Chowdhuri, Aamir Nazir and D. K. Saxena (2001) Effect of three chlorinated pesticides on hsr-? stress gene expression in transgenic Drosophila melanogaster. J. Biochem. Mol. Toxicol. Vol. 15(4): 173-186.
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 S. K. Pal, Aamir Nazir, I. Mukhopadhyay, D. K. Saxena and D. Kar Chowdhuri (2001) Internet: A major resource for toxicologists. Ind. J. Exp. Biol. Vol. 39: 1207-1213.