ANIL NILKANTH GAIKWAD
 
 

Scientist C
DTDD Division
Central Drug Research Institute,
Chattar Manzil Palace, Lucknow-226001.
 
E-Mail  anil_gaikwad@cdri.res.in
Educational qualifications M.S. Pharm (NIPER-M), Ph.D. (JNU)
Date of Birth 12.05.1977
 
POST DOCTORAL EXPERIENCE
 
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 High content studies on cell biology of macrophage-mycobacterium interaction at Max Planck Institute of Molecular Cell Biology and Genetics, Dresden Germany
 
AREA OF RESEARCH
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 Specialization: High throughput and High content biology
Expertise: Cell biology studies of host –parasite interaction
 
CURRENT AREAS OF INTEREST
Diabetes mellitus Type 2: High content approach for cell biology of Chemo/Genomic regulators of Glut4 translocation biology and insulin resistance
Tuberculosis: Mycobacterium and host macrophage interaction
 
SELECTED PUBLICATIONS
 
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 Gaikwad AN and Sinha S - Determinants of natural immunity against tuberculosis in an endemic setting: factors operating at the level of macrophage-Mycobacterium tuberculosis interaction (2008) - Clin Exp Immunol 151, 414-22
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 Ghosh S, Tiwari P, Pandey S, Misra AK, Chaturvedi V, Gaikwad A, Bhatnagar S and Sinha S - Synthesis and evaluation of antitubercular activity of glycosyl thio- and sulfonyl acetamide derivatives (2008) - Bioorganic and Medicinal Chemistry Letters 18, 4002-5
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 Singh BK, Yadav AK, Kumar B, Gaikwad AN, Sinha SK, Chaturvedi V and Tripathi RP - Preparation and reactions of sugar azides with alkynes: synthesis of sugar triazoles as antitubercular agents (2008) - Carbohydrate Research 343, 1153-1162
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 Das Sajal Kumar, Panda Gautam, Chaturvedi Vinita, Manju YK, Gaikwad Anil K and Sinha Sudhir. - Design, synthesis and antitubercular activity of diarylmethylnaphthol derivatives. (2007) - Bioorganic & Medicinal Chemistry Letters 17, 5586-5589
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 Panda Gautam, Parai Maloy Kumar, Das Sajal Kumar, Shagufta, Sinha Manish, Chaturvedi Vinita, Srivastava Anil K, Manju YK, Gaikwad Anil N and Sinha Sudhir. - Effect of substituents on diarylmethanes for antitubercular activity. (2007) - European Journal of Medicinal Chemistry 42, 410-419
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 Saquib M, Gupta MK, Sagar R, Prabhakar YS, Shaw AK, Kumar R, Maulik PR, Gaikwad AN, Sinha S, Srivastava AK, Chaturvedi V, Srivastava R and Srivastava BS - C-3 alkyl/arylalkyl-2,3-dideoxy hex-2-enopyranosides as antitubercular agents: Synthesis, biological evaluation, and QSAR study. (2007) - Journal of Medicinal Chemistry 50, 2942-2950
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 Tripathi, R P; Saxena, Nisha; Tiwari, V K; Verma, S S; Chaturvedi, Vinita; Manju, Y K; Srivastva, A K; Gaikwad, A; Sinha, S - Synthesis and antitubercular activity of substituted phenylmethyl- and pyridylmethyl amines (2006) - Bioorganic & Medicinal Chemistry, Volume 14, Issue 24, 8186-8196
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 Tripathi, R.P., Verma, S.S., Pandey, Jyoti, Agarwal, K.C., Chaturvedi, Vinita, Manju, Y.K., Srivastva, A.K., Gaikwad, A. and Sinha, S. - Search of antitubercular activities in tetrahydroacridines: Synthesis and biological evaluation (2006) - Bioorganic & Medicinal Chemistry Letters, Volume 16, Issue 19 , 5144-5147
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 Katiyar, D. , Tiwari, V.K., Tewari, N. , Verma, S.S. , Sinha, S. , Gaikwad, A. , Srivastava, A. , Chaturvedi, V. , Srivastava, R. , Srivastava, B.S. & Tripathi, R.P. - Synthesis and antimycobacterial activities of glycosylated amino alcohols and amines, (2005) - European Journal of Medicinal Chemistry, Volume 40, Issue 4, 351-360.
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 Panda, Gautam, Mishra, Jitendra Kumar, Sinha, Sudhir, Gaikwad, Anil K, Srivastava, Anil K, Srivastava, Ranjana & Srivastava, Brahm S. - 4-{10-(methoxybenzyl)-9-anthryl}phenol derivatives as new antitubercular agents. (2005) - Arkivoc, 29-45.
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 Sinha S., Kosalai K., Arora S., Namane A., Sharma P., Gaikwad A.N., Brodin P., Cole S.T. - Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics (2005) - Microbiology, 151, 2411-2419
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 Srivastava, T & Gaikwad, Anil K, Haq, Wahajul, Sinha, Sudhir & Katti, S.B. - Synthesis and biological evaluation of 4-thiazolidinone derivatives as potential antimicrobial agents. (2005) - Arkivoc, 120-30.
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 Tripathi, R.P. , Tiwari, V.K. , Tewari, N. , Katiyar, D. , Saxena, N. , Sinha, S. , Gaikwad, A. , Srivastava, A. , Chaturvedi, V. , Manju, Y.K. et al. - Synthesis and antitubercular activities of bis-glycosylated diamino alcohols, (2005) - Bioorganic & Medicinal Chemistry, 13, 5668-79
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 Tewari, N., Tiwari, V.K., Tripathi, R.P., Chaturvedi, V., Srivastava, A., Srivastava, R., Shukla, P.K., Chaturvedi, A.K., Gaikwad, A., Sinha, S. & Srivastava, B.S. - Synthesis of galactopyranosyl amino alcohols as a new class of antitubercular and antifungal agents. (2004) - Bioorganic and Medicinal Chemistry Letters, Volume 14, Issue 2, 2004, Pages 329-332.
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 R. Pathak, C. S. Pant, A. K. Shaw, A. P. Bhaduri, A. N. Gaikwad, S. Sinha, A. Srivastava, K. K. Srivastava, V. Chaturvedi, R. Srivastava and B. S. Srivastava, "Baylis-Hillman Reaction: Convenient Ascending Syntheses and Biological Evaluation of Acyclic Deoxy Monosaccharides as Potential Antimycobacterial Agents", Bioorganic & Medicinal Chemistry 10 :10, 2002, 3187-3196