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| DR.
MRS. ANURADHA DUBE NEE MISRA |
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Scientist G
Division of Parasitology
Central Drug Research Institute
Lucknow-226 001 |
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| POST-DOCTORAL
RESEARCH |
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Liverpool
School of Tropical Medicine, Liverpool, UK 1993 |
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Institute
of Primate Research, Nairobi, Kenya 1997 |
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Razi Institute
of vaccine and serum, Tehran, Iran 1999 |
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| RESEARCH
EXPERIENCE |
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27 years in
the area of chemotherapy and immunology of experimental
helminthic (15 years) and Leishmanial (12 years) infections. |
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| CURRENT
AREAS
OF INTEREST |
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Chemotherapy
and Immunology of visceral leishmaniasis |
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| SELECTED
PUBLICATIONS |
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Gupta Shraddha K, Kumar
Awanish, Samant Mukesh, Sundar Shyam, Singh Neeloo and
Dube Anuradha - Proteomic approaches for the
discovery of new targets for vaccine and therapeutics
against Leishmaniasis (2008) - Proteomics- Clinical
Applications 2, 372–386 |
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Kumar Pranav, Kumar Ashutosh,
Verma SS, Dwivedi Namrata, Singh Nasib, Siddiqi Mohammad
Imran, Tripathi RP, Dube Anuradha and
Singh Neeloo - Leishmania donovani pteridine reductase
1: Biochemical properties and structure-modeling studies
(2008) - Experimental Parasitology 120,
73-9 |
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Kumari Shraddha , Samant
Mukesh, Misra Pragya, Khare Prashant, Sisodia Brijesh,
Shasany Ajit K and Dube Anuradha - Th1-stimulatory
polyproteins of soluble Leishmania donovani promastigotes
ranging from 89.9 to 97.1kDa offers long-lasting protection
against experimental visceral leishmaniasis (2008)
- Vaccine 26, 5700-11 |
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Kumari Shraddha, Kumar
Awanish, Samant Mukesh, Singh Neeloo and Dube Anuradha
- Discovery of Novel Vaccine Candidates and Drug Targets
against Visceral Leishmaniasis using Proteomics and Transcriptomics
(2008) - Current Drug Targets 9,938-47
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Kumari Shraddha, Samant
Mukesh, Khare Prashant, Sundar Shyam, Sinha Sudhir and
Dube Anuradha - Induction of Th1-type
cellular responses in cured/exposed Leishmania infected
patients and hamsters against poly proteins of soluble
Leishmania donovani promastigotes ranging from 89.9-97.1
kDa (2008) - Vaccine 26, 4813-8 |
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Manandhar KD , Yadav TP,
Prajapati VK, Kumar S, Rai M, Dube Anuradha,
Srivastava ON and Sundar S - Antileishmanial activity
of nano-amphotericin B deoxycholate (2008) - Journal
of Antimicrobial Chemotherapy 62, 376-80 |
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Misra Pragya, Khaliq Tanvir,
Dixit Anshuman, Sengupta Souvik, Samant Mukesh, Kumari
Shraddha, Kumar Awanish, Kushawaha Pramod, Majumder Hemanta,
Saxena Anil, Narender T and Dube Anuradha
- Antileishmanial activity mediated by apoptosis and structure
based target study of Peganine hydrochloride dihydrate:
An approach for rational drug designing (2008)
- Journal of Antimicrobial Chemotherapy 62, 998-1002
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Singh N, Kumar R, Gupta
S, Dube A and Lakshmi V - Antileishmanial
activity in vitro and in vivo of constituents of sea cucumber
Actinopyga lecanora (2008) - Parasitol Research
103, 351-4 |
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Singh Nasib, Kumar A,
Gupta Prasoon, Chand K, Samant Mukesh, Maurya Rakesh and
Dube Anuradha - Evaluation of antileishmanial
potential of Tinospora sinensis against experimental visceral
leishmaniasis. (2008) - Parasitology Research
102, 561-5 |
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Tripathi Parul, Gupta
Shraddha K, Sinha Sudhir, Sundar Shyam, Dube Anuradha
and Naik Sita - Prophylactic efficacy of high molecular
weight antigenic fractions of a recent clinical isolate
of L. donovani against Visceral Leishmaniasis (2008)
- Scandinavian Journal of Immunology 68, 492-501
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Dube A,
Singh N, Saxena A and Lakshmi V. - Antileishmanial potential
of a marine sponge, Haliclona exigua (Kirkpatrick) against
experimental visceral leishmaniasis. (2007) -
Parasitology Research 101, 317-324 |
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Gupta SK, Sisodia BS,
Sinha S, Hajela K, Naik S, Shasany AK and Dube
A. - Proteomic approach for identification and
characterization of novel immunostimulatory proteins from
soluble antigens of Leishmania donovani promastigotes.
(2007) - Proteomics 7, 816-82 |
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Gupta Swati, Dube Anuradha
and Vyas Suresh P. - Antileishmanial efficacy of amphotericin
B bearing emulsomes against experimental visceral. (2007)
- Journal of Drug Targeting 15, 437-444 |
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Lakshmi V, Pandey K, Kapil
A, Singh N, Samant M and Dube A. - In
vitro and in vivo leishmanicidal activity of Dysoxylum
binectariferum and its fractions against Leishmania donovani.
(2007) - Phytomedicine 14, 36-42 |
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Samant M, Sahasrabuddhe
AA, Singh N, Gupta SK, Sundar S and Dube A
- Proteophosphoglycan is differentially expressed in sodium
stibogluconate-sensitive and resistant Indian clinical
isolates of Leishmania donovani. (2007) - Parasitology
134, 1175-1184 |
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Singh N, Samant M, Gupta
SK, Kumar A and Dube A - Age-influenced
population kinetics and immunological responses of Leishmania
donovani in hamsters. (2007) - Parasitology Research
101, 919-924 |
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Garg, Ravendra and Dube,
Anuradha - Animal models for vaccine studies
for visceral leishmaniasis (2006) - Indian Journal
of Medical Research, 123, 439-454 |
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Garg, Ravendra; Gupta,
Shraddha K; Tripathi, Parul; Hajela, K; Sundar, S; Naik,
S; Dube, Anuradha, - Leishmania donovani:
identification of stimulatory soluble antigenic proteins
using cured human and hamster lymphocytes for their prophylactic
potential against visceral leishmaniasis (2006)
- Vaccine, 24, 2900-2909. |
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Garg, Ravendra; Singh,
Nirpendra; Dube, Anuradha - Intake of
nutrient supplements affects multiplication of Leishmania
donovani in hamsters (2006) - Parasitology,
129, 685-691 |
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Hasan, A; Satyanarayana,
M; Mishra, A; Bhakuni, D S; Pratap, Ram; Dube, A; Guru,
P Y - Acyclic pyrazolo[3,4-d]pyrimidine nucleoside as
potential leishmaniostatic agent (2006) - Nucleosides,
Nucleotides & Nucleic Acids, 25, 55-60. |
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Sharma Sharad Kumar, Dube,
Anuradha, Ahmad Nadeem, Khan, Shazia, Saleem,
Iram, Garg, Ravendra and Mohammad, Owais - Non PC liposome
entrapped promastigote antigens elicit parasite specific
CD8+ and CD4+ T-cell immune response and protect hamsters
against visceral leishmaniasis (2006) - Vaccine,
24, 1800-1810 |
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Tripathi, P, Ray S, Sunder
Shyam, Dube Anuradha & Naik Sita.
- Identification of Leishmani donovani antigens stimulating
cellular immune responses in exposed immune individuals.
(2006) - Clinical & Experimental Immunology,
143, 380-88. |
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Tripathi, Shweta, Singh
Nasib, Shakya Shilpi, Dangi Anil, Misra-Bhattacharya Shailja,
Dube Anuradha & Kumar Nikhil - Landrace/gender-based
differences in phenol and thiocynate contents and biological
activity in Piper betel L. (2006) - Current Science,
91, 746-49 |
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Dube A.,
Singh N., Sundar S., Singh N. - Refractoriness to the
treatment of sodium stibogluconate in Indian kala-azar
field isolates persist in in vitro and in vivo experimental
models (2005) - Parasitology Research,
96, 216-223 |
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Garg, R; Gupta, S K; Tripathi,
P; Naik, S; Sundar, S; Dube, A, - Immunostimulatory
cellular responses of cured Leishmania-infected patients
and hamsters against the integral membrane proteins and
non-membranous soluble proteins of a recent clinical isolate
of Leishmania donovani, (2005) - Clinical And
Experimental Immunology, Volume 140, Issue 1,
149-156. |
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Isolation
of integral membrane proteins of Leishmania promastigotes
and evaluation of their prophylactic potential in hamsters
against experimental visceral leishmaniasis. Ravendra
Garg, J.K. Srivastava, A. Pal, S. Naik and Anuradha
Dube. Vaccine (accepted) 2004. |
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Intake of
nutrient supplements affects population kinetics of Leishmania
donovani in hamsters. Ravendra Garg, Nirpendra Singh and
Anuradha Dube. Parasitology (in press)
2004 |
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Efficacy Of
Human b Casein Fragment (54-59) And Its Synthetic Analogue
89/215 against Leishmania donovani in hamsters. P. Sharma,
Nasib Singh, Ravendra Garg, W. Haq, and Anuradha Dube
Peptides (in press), 2004 |
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Fluorescent
Leishmania: Applications to antileishmanial drug testing.
Neeloo Singh and Anuradha Dube. American Journal
of Tropical Medicine and Hygiene (in press) 2004
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Presbytis
entellus: A Primate Model for Parasitic Disease Research.
Anuradha Dube, P. Kalpana Murthy, S. K. Puri and
Shailja Misra-Bhattacharya. Trends in Parasitology
20(8) 358-360, 2004 |
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Successful
vaccination against Leishmania donovani infection in Indian
langur using Alum-precipitated Autoclaved L. major (ALM)
with BCG. Alka Misra, Anuradha Dube, Bindu Srivastava,
Preeti Sharma, J.K. Srivastava, J.C.Katiyar and Sita Naik.
Vaccine May 14; 19 (25-26): 3485-92,2001
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Leishmania
donovani: Cellular and humoral immune responses in Indian
langur monkey Presbytis entellus. Anuradha, J.K.,
Srivastava, P Sharma, A. Chaturvedi, J.C Katiyar and S.
Naik, Acta Tropica. 73,37-48,1999. |
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Efficacy of
a substituted methyl benzimidazole carbamate aainst developing
and adult helminth parasites. J.C. Katiyar, A. Misra,
S. Gupta, P.K.S. Visen, P.K. Murthy and A.B. Sen. Veterinary
Parasitology 23: 193-204,1987. |
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