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Dr. Archana Srivastava |
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Scientist F
Endocrinology Division
Central Drug Research Institute
Lucknow-226 001 |
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| Educational Qualifications |
M.Sc., Ph.D |
| E-Mail |
[email protected] |
| Date of Birth |
12.12.1950 |
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| Post-doctoral
Research Experience |
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Fogarty/
NIH fellowship ,Northwestern University , Department of
Biochemistry, Molecular Biology and Cell Biology Evanston,
IL, USA with Professor Erwin Goldberg, Ex- Noble Laureaute
(July 2004-June 2005) |
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WHO
Fellowship, Vanderbilt University, Department of Cell
Biology, Nashville (TN), USA with Professor Gary E. Olson
( April 1989 to July, 1991) |
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| CURRENT
AREAS OF INTEREST |
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Antifertility
- Development of contraceptives for male |
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Molecular
mechanisms of sperm maturation in mammalian epididymis
as target for post-testicular contraception |
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Development
of inhibitors of sperm specific ion channel as antispermatogenic
agents |
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Development
of sperm hyaluronidase enzyme inhibitors as contraceptive
agents |
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Molecular
characterization and significance in fertility/infertility
of post-translationally modified, maturation dependent
sperm membrane glycoproteins of mammalian epididymis |
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| RESEARCH
EXPERIENCE |
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Male
Reproductive Biochemistry, Andrology, Antifertility |
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Post-testicular epididymal sperm maturation |
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Contraception |
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Infertility |
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| SELECTED
PUBLICATIONS |
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Archana
Srivastav, A Chandra, M Singh, F Jamal, P Rastogi,
S M Rajendran, FW Bansode, V Lakshmi ( 2009)
Inhibition of hyaluronidase activity of human and rat
spermatozoa in vitro and antispermatogenic activity in
rats in vivo by Terminalia chebula, a flavonoid rich plant
. Reproductive Toxicology (Published
on line, DOI: 10.1016/j.reprotox.2009.11.001) |
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A Chandra,
KR Srinivasan, F Jamal, PK Mehrotra, RL Singh and Archana
Srivastav (2008)
Post-translational modifications in glycosylation status
during epididymal passage and significance in fertility
of a 33kDa glycoprotein (MEF3) of rhesus monkey (Macaca
mulatta). Reproduction 135 761-770. |
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A Chandra, RL Singh and
Archana Srivastav (2007) Mammalian epididymis
and its role in reproduction: a review. Journal
of Ecophysiology & Occupational Health 7
201-207 |
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A Chandra, F Jamal, M
Singh, A Pande, V Das, RL Singh and Archana Srivastav
(2007)
Significance of a fertility inhibiting 33 kDa (MEF3) glycoprotein
of rhesus monkey (Macaca mulatta) in human infertility.
Journal of Ecophysiology & Occupational Health
7 209-215. |
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Archana Srivastav,
B Singh, A Chandra, F Jamal, M Y Khan and S R Chowdhury
(2004) Partial characterization, sperm
association and significance of N- and O- linked glycoproteins
of epididymal fluid (EF) of rhesus monkey (Macaca mulatta)
Reproduction (UK) , 127, 343-357. |
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Archana Srivastav
(2000) Maturation dependent glycoproteins containing
both N-& O- linked oligosaccharides of epididymal
sperm plasma membrane of rhesus monkey (Macaca mulatta).
J. Reprod Fert, 119: 241-252. |
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Archana Srivastava
& Olson GE (1996) Studies on (3H)-palmitate
binding proteins of rat spermatozoa: a post-translational
modification of membrane proteins by fatty acid acylation.
J Reprod Fert, 108: 245-251 |
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Archana Srivastava
& Olson GE (1991) Glycoprotein changes in the rat
sperm plasma membrane during maturation in the epididymis.
Mol. Reprod. & Dev., 29: 357-364. |
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Archana Srivastava,
Maikhuri JP & Setty BS (1987) Evaluation
of STS-557 as an oral contraceptive in male rat. Contraception,
36 : 253-272. |
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Archana Srivastava,
Chowdhury AR & Setty BS (1986) Testicular
regulation and subcellular distribution of zinc in the
epididymis and vas deferens of rhesus monkey (Macaca mulatta).
Acta Endocr. (Kbh.), 113 : 440-449. |
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Setty BS, Jehan Q, Archana
Srivastava & Kamal N (1986)
Biological response of the rat epididymis to estrogen.
Exp. Clin. Endocrinol., 87 : 229-238. |
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Archana Srivastava
& Setty BS (1985). The distribution
of zinc in the subcellular fractions of the rhesus monkey
testis. Biol. Tr. Element Res., 7 : 83-87. |
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Archana Srivastava,
Maikhuri JP, Chowdhury AR & Setty BS (1985).
Possible role of zinc in the extragonadal antifertility
action of a -chlorohydrin in rat. Life Science Advances,
4 (1A) : 1-7. |
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Archana Srivastava,
Chopra SK & Dasgupta PR (1984) Biochemical
analysis of human seminal plasma II. Protein, non-protein
nitrogen, urea, uric acid and creatine. Andrologia,
16 : 265-268. |
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Archana Srivastava,
Chowdhury AR & Setty BS (1984) Zinc content in the
epididymis, vas deferens, prostate and seminal vesicles
of juvenile rhesus monkey (Macaca mulatta) : effect of
androgen and estrogen. Prostate, 5 :
153-158. |
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Archana Srivastava,
Chowdhury AR & Setty BS (1983) Zinc content of maturing
spermatozoa in estrogen treated rats. Int. J.
Androl., 6 : 103-108. |
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Archana Srivastava,
Chopra SK & Dasgupta PR (1983) Biochemical analysis
of human seminal plasma. I. Fructose, ascorbate, cholesterol,
adenosine tri-phosphatase and lactate dehydrogenase. Andrologia,
15 : 431-435. |
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Archana Srivastava,
Dhar JD, Chowdhury AR, Chandra H & Setty BS (1982)
Zinc in epididymal spermatozoa of rhesus monkey (Macaca
mulatta). Archs. Androl., 3 :117-120. |
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Dasgupta PR, Chopra SK,
Kar AB & Archana Srivastava (1973)
Seminal urea level and sperm count. Lancet,
1 : 770, 1973. |
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