Dr. ARUN KUMAR SHAW
 
Scientist E II
Medicinal and Process Chemistry Division
Central Drug Research Institute
Lucknow-226001, India
 
Educational qualifications M.Sc. Ph.D.
Date of Birth July 07, 1955.
Phone Nos. +91-0522-2612411-18-Ext 4334, Mobile + 9415403775
Fax No. +91-0522-2623405
E- mail akshaw55[at]yahoo dot com
 
RESEARCH EXPERIENCE
 
•
 Natural Products Chemistry (25 years), Synthetic Organic Chemistry (18 years), Medicinal Chemistry (14 years).
 
POST DOCTORAL RESEARCH
 
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 CSIR-DAAD Visiting Scientist, University of Rostock, Germany, April-June 2000
 
CURRENT AREAS OF RESEARCH
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 Design, Synthesis & Development of Target- based Anti-tubercular agents
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 Synthetic Carbohydrate & Natural Products Chemistry
 
GROUP MEMBERS
 
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 Supervising three research students for their Ph D degree
SELECTED PUBLICATIONS
 
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 Stereoselective synthesis of highly O-functionalized enantiopure 2,3,4- trisubstituted tetrahydrofurans by tandem debenzylative cyclization of glycal derived 2,3-epoxy alcohols. L. Vijaya Raghava Reddy, Abhijeet Deb Roy, Raja Roy and Arun K. Shaw. Chem. Commun. 2006, 3444-3446.
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 Studies on epoxidation of enantiomerically pure 2,3-dideoxy hex-2-enitols: a convenient access to highly functionalized enantiomerically pure tetrahydrofuran derivatives. Ram Sagar, L. Vijaya Raghava Reddy and Arun K. Shaw. Tetrahedron: Asymmetry 2006, 17, 1189-1198.
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 An efficient synthesis of 2,3-dideoxy-?,ß-unsaturated carbohydrate enals by mixed Lewis acid (HfCl4 and ZnI2) catalyzed hydration of glycals. Mohammad Saquib, Ram Sagar, Arun K. Shaw. Carbohydr. Res. 2006, 341, 1052-1056.
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 Reductive opening of glycal derived highly functionalized 2,3-epoxy-1-iodides with zinc dust: an efficient method for the synthesis of acyclic long chain polyhydroxylated terminal alkenic alcohols. L.Vijaya Raghava Reddy, Ram Sagar, Arun. K. Shaw. Tetrahedron Lett. 2006, 47, 1753-1756.
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 Neridienone A, a pregnane from the roots of Nerium oleander. Rishi Kumar, Ram Sagar, Arun. K. Shaw, Prakas. R. Maulik. Acta Cryst. 2005, E61, o3905-o3907.
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 CP-MLR directed QSAR studies on the antimycobacterial activity of functionalized alkenols-topological descriptors in modeling the activity. Manish K. Gupta, Ram Sagar, Arun K. Shaw and Yenamandra S. Prabhakar* Bioorganic & Medicinal Chemistry (2005), 13, 343-351
•
 Diastereoselective annulation of 4-hydroxypyran-2H-ones with enantiopure 2,3-dideoxy- -unsaturated sugar aldehydes derived from respective glycals. Ram Sagar, Pushpa Singh, Rishi Kumar, Prakas R. Maulik and Arun K. Shaw* Carbohydrate Research (2005), 340, 1287-1300
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 A convenient approach towards separation and identification of triterpenes of delta12 lupane series. Ram Sagar, Namrata Dilip Dhoke and Arun K Shaw. Indian Journal Chem Sec. B, (2004), 43B, 2446-2451.
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 Substrate Controlled A Very High Diastereoselective Mortia-Baylis-Hillman Reaction: A Remote Activation on the Diastereoface Selectivity in Synthesis of C-3-Branched Deoxysugars. Ram Sagar, C.S. Pant and R. Pathak and A.K. Shaw. Tetrahedron (2004), 60, 11399-11406.
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 Reinvestigation of the mercuration–demercuration reaction on alkylated glycals: an improved method for the preparation of 2,3-dideoxy-alpha, beta-unsaturated carbohydrate enals. Ram Sagar, Rashmi Pathak and Arun K. Shaw. Carbohydrate Research (2004), 339, 2031-2035.
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 A Common Sugar as Model for Many - sided Natural Product Modification. From D - Fructose via D - Tagatose to 2 - Difluoro - chloromethylated D - Arabinohexopyranos - 5 - ulose Derivatives, R. Miethchen, S. Tews, A. K. Shaw, S. Röttger, H. Reinke. J. Carbohydr. Chem.(2004), 23, 147- 161.
 
PATENT FILED
 
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 Novel series of unsaturated C-3 aryl and alkyl substituted 2,3- dideoxy glucopyranosides as potential anti-tubercular agents. Ram Sagar, Mohd Saquib, Arun K Shaw, Anil N Gaikwad, Sudhir K Sinha, Anil Srivastava, Vinita Chaturvedi, Manju Y K, Ranjana Srivastava and B S Srivastava.