|
Assay
|
Model system
|
Disease area
|
Sample
quantity required
|
Scientists involved
|
Plasmodium falciparum
SYBR Green based assay
|
In- vitro: whole cell assay
|
Malaria |
15 mg | r
Dr Kumkum Srivastava
|
Plasmodium yoelii ( N-67) - Swiss mice
Plasmodium yoelii ( MDR) - Swiss mice
|
In-vivo: Primary model for Blood Schizontocidal assay
|
Malaria |
200 mg
|
Dr Renu Tripathi
|
|
Plasmodium yoelii ( N-67) - Anopheles stephensi - Swiss mice |
In-vitro: Primary model for tissue Schizontocidal assay |
Malaria
|
200 mg
|
Dr Renu Tripathi
|
|
Plasmodium cynomolgi - Rhesus monkey
|
In-vivo: Secondary model for blood Schizontocidal /
Anti-relapse assay
|
Malaria
|
3.0 gm |
Dr Renu Tripathi
|
|
Leishmania donovani -Macrophase- Amastigote Luciferase based assay |
In vitro: whole cell assay |
Leishmaniasis |
15 mg |
Dr Neena Goyal
|
|
Leishmania donovani- Macrophase- Amastigote GFP based assay
|
In vitro: whole cell assay
|
Leishmaniasis
|
15 mg
|
Dr Anuradha Dube
|
|
Leishmania donovani Golden hamster chronic model
|
In vivo: assay
|
Leishmaniasis
|
300 mg
|
Dr Neena Goyal
Dr Anuradha Dube
|
|
Brugia malayi- MTT and motility assay
|
In vitro: whole parasite assay
|
Filariasis
|
20 mg |
Dr. Mrigank Srivastava
|
| Brugia malayi- Adult transplanted in JIRD
|
In vivo: Primary assay
|
Filariasis
|
300 mg
|
Dr. Mrigank Srivastava
|
|
L3 induced Brugia malayi- Mastomys
|
In vivo: Secondary model
|
Filariasis
|
500 mg
|
Dr. Mrigank Srivastava
|
