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  CENTPROPAZINE (Antidepressant)
 

Interest in the development of antidepressants had its beginning in early sixties after the introduction of imipramine. This was followed by introduction of several antidepressants belonging to the major groups of "tricyclic antidepressant" and "monoamine oxidase inhibitors". However, following their increasing use in psychiatry and general practice, several limitations were observed such as they were not effective in 20-30% patients; the onset of effect takes 2-3 weeks; excess consumption risk by patients having suicidal tendency; and adverse effects of anticholinergic and cardiovascular nature.

Limitations of existing antidepressant drugs have led to persistent global efforts to develop newer drugs. Centpropazine is a new antidepressant compound with a different pharmacological profile. The early clinical studies showed it to be safe and well tolerated in normal human volunteers. Multicentric clinical efficacy studies were carried out in nearly 250 patients suffering from depression. These studies reveal Centpropazine to have comparable response rate with remarkably safer tolerability profile.

 
  CONSAP (local contraceptive cream, spermicide)
 
C D R I's Contraceptive development programme has acieved anther great success in this area of national and international importance. It's contraceptive Cream, CONSAP has now been approved bu the Drugs Controller General of India for its marketing and use. CONSAP is a sterile contraceptive cream developed from the saponins obtained from soap nuts (Reetha) collected from the plant, Sapindus mukorosii. The cream is recommended for all women of reproductive age group who want to space their children. It is safe and free from systemic side effects on continuous prolonged use.The preparation has been developed by using saponins from the soapnut or reetha (Sapindus mukorossi). The cream went through all regulatory testing and Phase I, II and III clinical trials and proved to be an effective contraceptive product. DCG(I) cleared the cream for use.
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The CONSAP Cream has been licensed to the Hindustan Latex Limited who are going to market the product in very near future
 
 
 
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