Visiting Fellow, National Tsing Hua University, Taiwan; NSERC

Synthetic Organic Chemistry; Bioorganic and Medicinal Chemistry; Chemical Biology
Sub Area of Research:
i) Design, synthesis and development of target based new chemical entities for Breast Cancer, Tuberculosis and Malaria;
ii) [6-5-6] and [6-5-5]tricyclic core embedded new heterocycles (Taiwaniaquinoid like structures) as anticancer agents;
iii) Organic synthesis of target and diversity oriented natural products (alkaloids) and amino acid based natural product like designed chiral molecules through identification of new synthetic methodologies;
iv) Design, synthesis and bioevaluation of benzofused oxaheterocycles using b-Hydroxy-a-tosyloxy Esters obtained from Sharpless epoxidation and dihydroxylation reaction
Ongoing/Completed Project Title:
a)“Design and Development of Tissue Selective Antiestrogens” of Rs. 11,59,000/- from DST, New Delhi has been completed as Principal Investigator (PI). b) “Design and Synthesis of Novel SERMs for the management of Osteoporosis and other estrogen related disorders” of Rs. 17,00,000/- from ICMR, New Delhi is ongoing as PI. c)“Diversity Oriented Organic Synthesis of Small But Smart Molecules In Drug Discovery Research” of Rs. 20,00,000/- from DST, New Delhi is ongoing as PI. d)Member of Task force project on “Reproductive Health Research” funded by Ministry of Health. e)Member of CSIR Task force project on “Microbial Infections” and “Synthetic Biology and Metabolic Engineering of Azadirachtin biosynthetic pathway”. f)“Amino Acids as chiral Synthons: Development of new synthetic protocols for creating Natural Products and related diversity in quest for anticancer agent” of Rs. 35 lakhsfrom DST,New Delhi is ongoing as PI. g)“Design, synthesis and evaluation of new chemical entities against atypical mycobacterium, Mycobacterium fortuitum” of Rs. 40 lakhs from ICMR, New Delhi and is ongoing as PI.