DR. GOPAL GUPTA
 


Scientist E-I
Division of Endocrinology
Central Drug Research Institute
Lucknow 226 001, India

 
Phone +91-522-2612411- 18 PABX Ext 4396
Fax +91-522-2623405
E-Mail ji_gupta[at]yahoo dot co dot in
Educational qualifications M.Sc., Ph.D.
Date of birth 09-03-1962
 
RESEARCH AREAS
 
Male Reproductive Biology & Contraception, Biochemistry, Local Contraceptives, Microbicides including topical anti-HIV agents.
 
CURRENT AREAS OF INTEREST
 
Development of prophylactic topical contraceptives (microbicides/spermicides), Spermatogenesis, Sperm enzyme inhibitors, anti-HIV agents.
 
SELECTED PUBLICATIONS
 
Rajeev K Jain, Jagdamba P Maikhuri, S T V S Kiran Kumar, Vishnu L Sharma, Anil K Dwivedi, Kalyan Mitra, Virendra K Bajpai, Gopal Gupta. Novel disulfide esters of carbothioic acid as potent, non detergent spermicides with low toxicity to Lactobacillus and HeLa cells in vitro. Human Reproduction 2006 (published online).
Priti Ojha, Janak D Dhar, Anil K Dwivedi, Ram L Singh, Gopal Gupta. Rat testicular germ cell type(s) targeted by anti spermatogenic agents in vivo and their recovery on withdrawal of treatment – a flow cytometric study. Animal Reproduction Science 2006 (IN PRESS)
P Ojha, JD Dhar, AK Dwivedi, RL Singh, G Gupta : Effect of antispermatogenic agents on cell marker enzymes of rat Sertoli cells in vitro. Contraception 73:102-106, 2006
STVS Kiran Kumar, VL Sharma, M Kumar, PK Shukla, P Tewari, RK Jain, JP Maikhuri, D Singh, Gopal Gupta, MM Singh. Synthesis of benzenepropanamine analogues as non-detergent spermicides with antitrichomonas and anticandida activities. Bioorg Med Chem. 2006 14:6593-6600.
VS Kumar, VL Sharma, P Tiwari, D Singh, JP Maikhuri, G Gupta, MM Singh: The spermicidal and antitrichomonas activities of SSRI antidepressants. Bioorg Med Chem Lett 16:2509-2512, 2006
G Gupta, RK Jain, JP Maikhuri, PK Shukla, M Kumar, AK Roy, A Patra, V Singh, S Batra. Discovery of substituted isoxazolecarbaldehydes as potent spermicides, acrosin inhibitors and mild anti-fungal agents. Human Reproduction 20:2301-2308, 2005
G. Gupta: Microbicidal spermicides or spermicidal microbicides ? Eur J Contracept Reprod Health Care 10:212-8, 2005
Effect of spermicides on lactobacillus acidiphilus in vitro-nonoxynol-9 vs. Sapindus saponins. P Ojha, J P Maikhuri and G Gupta, Contraception 68: 135-138, 2003
Mechanism of action of some Acrylophenones, Quinolines and Dithiocarbamate as potent Spermicidal Agents, JP Maikhuri, AK Dwivedi, JD Dhar, BS Setty and G Gupta, Contraception Vol. 67, 403-408, 2003
Gupta G, Maikhuri JP, Setty BS, Dhar JD. Seasonal variations in daily sperm production rate of rhesus and bonnet monkeys. J Med Primatol. 2000 29:411-4
Changes in Carbohydrate Metabolism of Testicular Germ Cells During Meiosis in the Rat, M. Bajpai, G. Gupta and B.S. Setty, European Journal of Endocrinology 138:322-327, 1998.