DR.S.B.KATTI
 
  Scientist G
Medicinal & Process Chemistry Division
Date of Birth 28th November, 1953
Educational Qualifications M. Sc. Ph.D
Email [email protected]
 
POST-DOCTORAL RESEARCH
 
University of Chicago, July 1995 to June 1997
University of California (Santa Cruz) July 1997 to June 2001
 
RESEARCH AREAS
 
Medicinal Chemistry and Bioorganic Chemistry
 
CURRENT AREAS OF INTEREST
 
Design and synthesis of non-nucleoside reverse transcriptase inhibitors, anti-fungal and antimicrobial agents, QSAR.
 
PATENTS
 
Indian Seven
Seven
US patent Two
EU patent One
PCT One
 
SELECTED PUBLICATIONS
 
Rawal Ravindra K, Katti SB, Kaushik-Basu Neerja, Arora Payal and Pan Zhenhua. Non-nucleoside inhibitors of the hepatitis C virus NS5B RNA-dependant RNA polymerase: 2-Aryl-3-heteroaryl-1,3-thiazolidin-4-one derivatives.(2008) Bioorganic and Medicinal Chemistry Letters 18, 6110-6114
Rawal Ravindra K, Tripathi Rajkamal, Katti SB, Pannecouque Christophe and De Clercq Erik. Design and synthesis of 2-(2,6-dibromo-phenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents.(2008) Eur. J. Med. Chem. 43, 2800-2806
Rawal Ravindra K. Tripathi Rajkamal, Kulkarni S. Paranjape R, Katti SB, Pannecouque Christophe and De Clercq Erik. 2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-ylmethyl-1,3-thiazolidin-4-one: Anti-HIV agents. (2008) Chemical Biology & Drug Design 72, 147-54
Solomon VR, Haq W, Smilkstein M, Srivastava K, Rajakumar S, Puri SK and Katti SB. Synthesis and antimalarial activity of novel side chain modified antimalarial agents derived from 4-aminoquinoline. (2008) Med. Chem. 4, 446-56
Rawal Ravindra K, Kumar Ashutosh, Siddiqi Mohammad Imran and Katti Setu B - Molecular docking studies on 4-thiazolidinones as HIV-1 RT inhibitors. (2007) - Journal of Molecular Modeling (Online) 13, 155-161
Rawal Ravindra K, Tripathi Rajkamal, Katti SB, Pannecouque Christophe and Clercq Erik De - Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents. (2007) - Bioorganic & Medicinal Chemistry 15, 3134-3142
Rawal Ravindra K, Tripathi Rajkamal, Katti SB, Pannecouque Christophe and De Clercq Erik - Design, synthesis and evaluation of 2-aryl-3-heteroaryl-1,13-thiazolidin-4-ones as anti-HIV agents. (2007) - Bioorganic & Medicinal Chemistry 15, 1725-1731
Rawal RK, Prabhakar YS and Katti SB - Molecular surface features in modeling the HIV-1 RT inhibitory activity of 2-(2,6-disubstituted phenyl)-3-(substituted pyrimidin-2-yl)-thiazolidin-4-ones. (2007) - QSAR & Combinatorial Science 26, 398-406
Rawal RK, Tripathi RK, Katti SB, Pannecouque C and De Clercq E - Synthesis and biological evaluation of 2,3-diaryl substituted-1,3-thiazolidin-4-ones as anti-HIV agents. (2007) - Med Chem 3, 355-363
Solomon V Raja, Haq W, Srivastava Kumkum, Puri Sunil K and Katti SB - Synthesis and antimalarial activity of side chain modified 4-aminoquinoline derivatives (2007) - Journal of Medicinal Chemistry 50, 394-398
Raghunandan, Reshmi, Rawal RK, Katti SB & Maulik PR. - 2-(2,6-Dichlorophenyl)-3-(substituted pyrimidin-4-one). (2006) - Acta Crystallographica, E62, 5349-51.
Rawal, Ravindra K, Kumar Ashutosh, Sidiiqi M Imran & Katti SB. - Molecular docking studies on 4-thiazolidinones as HIV-1 RT inhibitors. (2006) - J Molecular Modeling, 13, 155-61.
Solomon, V Raja; Haq, W; Puri, Sunil K; Srivastava, Kumkum; Katti, S B - Design, synthesis and antimalarial activity of a new class of iron chelators (2006) - Med Chem, 2, 133-138
Conformation of an immunoreactive undecapeptide fragment (1-20) of Aspf1 by NMR and molecular modeling, P. Desai, E. Coutinho, S. Srivastava, W. Haq and S. B. Katti, Letters in peptide sciences, 9 (1): 21-34, (2002)
Carbodiimide mediated synthesis of 4-thiazolidinones by one-pot three-component condensation, T. Srivasatva, W. Haq and S. B. Katti, Tetrahedron, 58, 7619-7624 (2002)
Crystal and molecular structure of 3'-Deoxyguanosine-N(2)-isobutyryl dihydrate, S. Thiyagarajan, P. Karthe, S. S. Rajan, N. Gautam, A. Kumar and S. B. Katti. Cryst. Res. Technol. (2001), 36, 485-492.
The importance of phosphate contacts for the interaction of EcoRI restriction endonuclease with its recognition sequence probed by chiral methylphosphonates, O. Rosati, T. K. srivastava, S. B. Katti and J. Alves, Biochem. Biophys. Res. Commu. (2002), 295, 198-205
Conformational rigidity introduced by 2', 5'-phosphodiester links in DNA, Anil Kumar, D. Dass, M. Atreyi, M. V. R. Rao and S. B. Katti. Nucleosides, Nucleotides and Nucleic Acids, (2001), 20, 1783-1796.
Structural insight into oxybenzotriazole based coupling reagents, T. K. Srivastava, W. Haq, S. Bhanumati, D. Velmurgan, U. Sarma, N. R. Jagannathan and S. B. Katti. Protein and Peptide Letters, (2001), 8, 39-44