Dr. J.K. SAXENA
...
Chief Scientist
Division of Biochemistry
Central Drug Research Institute,
P.O. Box No. 173
Lucknow 226031
 
 
E-Mail jk_saxena@cdri.res.in jkscdri[at]yahoo dot com
Educational qualifications M.Sc., Ph.D.
Phone No. 0522-2772450  Extn. 4963
Fax No.

0522-2771941

Date of Birth 10.10.1955
 
POST DOCTORAL RESEARCH
 
National Institute of Health, Bethesda (USA)
Department of Biochemistry, Mahidol University, Bangkok, Thailand.
 
RESEARCH EXPERIENCE
 
Biochemistry of Parasites (25 years)
Molecular Genetics (10 years)
Biotechnology (5 years)
 
CURRENT AREAS OF INTEREST
 
Characterization, Cloning and expression of enzymes/receptor to be utilized as chemotherapeutic target(s).
SELECTED RECENT PUBLICATIONS
 
Bhatia G, Puri Anju, Maurya R, Yadav PP, Khan MM, Saxena AK and Saxena JK - Antidyslipidemic and antioxidant activities of different fractions of Pongamia pinnata (Lin) fruits (2008) - Med Chem Research 17, 281-289
Joshi S, Singh AR, Kumar A, Misra PC, Siddiqi MI and Saxena JK - Molecular cloning and characterization of Plasmodium falciparum transketolase (2008) - Mol Biochem Parasitol. 160, 32-41
Khan MM, Saxena R, Puri Anju, Chander R, Khanna AK, Saxena AK and Saxena JK - Regulation of glycogen metabolism by antidyslipidemic action of gemfibrozil and cholestyramine in dyslipidemic diabetic hamster model (2008) - Med Chem Research 17, 245-257
Kumar A, Saxena JK and Chauhan PMS - Synthesis of 4-amino-5-cyano -2, 6-Disubsituted pyrimidines as a potential antifilarial DNA topoisomerase II Inhibitors (2008) - Medicinal Chemistry 4, 577-85
Sashidhara KV, Rosaiah JN, Bhatia G and Saxena JK. - Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents (2008) - Eur. J. Med. Chem. 43, 2592-6.
Sethi A, Paswan S, Srivastava S, Khare NK, Bhatia A, Kumar A, Bhatia G, Khan MM, Khanna AK and Saxena JK - A new pregnane glycoside from Marsdenia roylei as potential antioxidant and antidyslipidemicagents (2008) - J Asian Nat. Prod Res. 10, 1023-8
Singh AR, Joshi S, Arya R, Kayastha AM, Srivastava KK, Tripathi LM and Saxena JK - Molecular cloning and characterization of Brugia malayi hexokinase (2008) - Parasitol Int. 57, 354-61
Srivastava S, Joshi Shweta, Singh Alok Ranjan, Yadav, Sarika Saxena AS, Ram VJ, Chandra S and Saxena JK - Oxygenated chalcones and bischalcones as a new class of inhibitors of DNA topoisomerase of malarial parasites (2008) - Med Chem Research 17, 234-244
Verma SK, Bansal I, Vedi S, Saxena JK, Katoch VM and Bhattacharya SM - Molecular cloning, purification and characterisation of myosin of human lymphatic filarial parasite Brugia malayi. (2008) - Parasitol Research 102, 481-9
Sethi Arun, Maurya Atul, Tewari Vibha, Srivastava Sanjay, Faridi Shaheen, Bhatia Gitika, Khan MM, Khanna AK and Saxena JK - Expeditious and convenient synthesis of pregnanes and its glycosides as potential anti-dyslipidemic and anti-oxidant agents. (2007) - Bioorganic & Medicinal Chemistry 15, 4520-4527
Singh SK, Joshi S, Singh AR, Saxena JK and Pandey DS. - DNA binding and topoisomerase ii inhibitory activity of water-soluble ruthenium(ii) and rhodium(iii) complexes. (2007) - Inorg Chem 46, 10869-10876