Dr. (Mrs.) KALPANA BHANDARI
 



Scientist F
Medicinal & Process Chemistry Division
 
Educational qualifications M.Sc., Ph.D.
Date of birth 20.4.1951
 
 POST-DOCTORAL RESEARCH
 
•
 University College London ,U.K. from July 1995 to Nov.1995
 
RESEARCH EXPERIENCE
 
•
 Synthetic Organic Chemistry (26 years)
 
CURRENT AREAS OF INTEREST
 
•
 Medicinal Organic Chemistry
 
SELECTED PUBLICATIONS
 
•
 Bhandari Kalpana, Srinivas N, Sharma Lata, Srivastava Shipra, Nath Amar and Nath C - Substituted urea/thiourea derived from fluoxetine as potent appetite suppressants (2008) - Med Chem Research 17, 103-113
•
 Srinivas Nagarapu and Bhandari Kalpana - Proline-catalyzed facile access to Mannich adducts using unsubstituted azoles (2008) - Tetrahedron Letters 49, 7070-7073
•
 Bhandari Kalpana and Srivastava Shipra - Obesity; overview and management. (2007) - Current Bioactive Compounds 3, 278-290
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 Bhandari, Kalpana; Srivastava, Shipra; Shankar, Girija and Nath, Chandishwar - Synthesis and appetite suppressant activity of 1-aryloxy-2-substituted aminomethyltetrahydronaphthalenes as conformationally rigid analogues of fluoxetine (2006) - Bioorganic & Medicinal Chemistry, 14, 2535-44.
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 Bhandari, Kalpana , Srivastava, Shipra , Shanker, Girija & Nath, Chandishwar - Substituted propanolamines and alkylamines derived from fluoxetine as potent appetite suppressants, (2005) - Bioorganic & Medicinal Chemistry, Volume 13, Issue 5, 1739-1747.
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 Bhandari, K., Srivastava, S. & Shankar, G. - Synthesis of tetrahydronaphthyl thioureas as potent appetite suppressants. (2004) - Bioorganic and Medicinal Chemistry, Volume 12, Issue 15, 1 August 2004, Pages 4189-4196.
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 Sharma, V.L., Bhandari, K., Shankar, G., Singh, H.K., Srivastava, P. & Pandey, V.C. - Synthesis, CNS and chloroquin resistance reversal activity of benzenepropanamines. (2004) - Indian Journal of Chemistry - Section B , Volume 43, Issue 1, 2004, Pages 207-211.
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 Srivastava, S., Bhandari, B. & Sharma, V.L. - A facile synthesis of 3,4-disubstituted-1,5-dihydro-2H-3-pyrrolin-2-one. (2004) - Indian J. Chem., 43B, 2467-70.
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 Sharma, V.L., Bhandari, K., Shankar, G., Singh, H.K., Srivastava, P. & Pandey, V.C. - Synthesis, CNS and chloroquine resistance reversal activity of benzenepropamines. (2003) - Indian J. Chem., 42, 2668.
•
 V.L. Sharma, Kalpana Bhandari, Girija Shanker, H.K. Singh, Pratima Srivastava and V.C. Pandey, "Phenylpropylamines: Synthesis, CNS and Chloroquin resistance reversal activity" . Med. Chem. Res., 2001, 10(718), 541.
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 Kalpana Bhandari, V.L. Sharma, C.M. Singh, Girija Shanker and H.K. Singh, "Synthesis of 1-amino-1,2,3,4-tetrahydronaphthalene-2-ols via epoxide ring opening as possible antidepressant and anorexigenic agents" Indian J. Chem., 2000, 39B(6), 468-471.
•
 J. C. Rosa, D. Galanakis, A. Piergentili, K. Bhandari, C.R.Ganellin, P. M. Dunn and D. H. Jenkinson, Synthesis, Molecular Modelling, and pharmacological Testing of Bis-Quinolium Cyclophanes: Potent, Non-Peptidic Blockers of the Apamin-Sensitive Ca 2+- Activated K+ Channel, CHEMTRACTS-ORGANIC CHEMISTRY 13: 439-442 (2000).
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 J. Campos Rosa, D. Galanakis, A. Piergentili ,K. Bhandari, C.Robin Ganellin, Philip M. Dunn and Donald H. Jenkinson, Synthesis Molecular Modelling, and pharmacological Testing of Bis-Quinolium Cyclophanes: Potent, Non-Peptidic Blockers of the Apamin-Sensitive Ca 2+- Activated K+ Channel, J. Med. Chem ,2000, 43, 420-431.
•
 Kalpana Bhandari, V.L. Sharma and C.M. Singh, "An unusual Beckmann rearrangement of 17-oximino-3 -pyrrolidinoandrost-5-ene". Indian J. Chem., 1997, 36B(4), 352-353.
•
 K. Bhandari, Vishnu L. Sharma and Sunil K. Chatterjee, "A convinient method for the reduction of amides to corresponding amines".Chemistry & Industry, 1990, 547-48.