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DR. (Ms) KANCHAN HAJELA |
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Scientist F
Medicinal and Process Chemistry Division
Central Drug Research Institute
Chattar Manzil Palace
Lucknow 226001, UP, India
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| Phone No. |
+91-0522-2612411-18 Ext.
4463 (cabin), 4334 (lab) |
| Fax No. |
+91-0522-2643405, 2623938 |
| E- mail |
kanchan_hajela@cdri.res.in |
| Educational qualifications |
M.Sc., Ph D. |
| Date of Birth |
24.06.1957 |
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| RESEARCH
EXPERIENCE |
25 Years |
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| POST
-DOCTORAL RESEARCH |
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Post Doctoral
Research Fellow. Dept.of Medicinal Chemistry Univ. of
Mississippi,MS,USA 20th Jan.2002-15th Jan.2003
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| SPECIALISATION |
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Synthetic
Organic and Medicinal Chemistry currently working in
the area of female reproductive health research.
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| CURRENT
AREAS OF INTEREST |
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Design and
Synthesis of bioactive molecules particularly non steroidal
heterocyclic molecules as estrogen receptor modulators
(agonists/ antagonists) for use in the management of post-
menopausal disorders such as breast cancer, osteoporosis,
antifertility etc. |
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| SELECTED
PUBLICATIONS |
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Synthesis
and Biological Evaluation of 3, 4, 6-Triaryl -2-Pyranones
as a New Class of Anti-breast Cancer Agents.Ravi Shankar,
Bandana Chakravarti, Uma Sharan Singh, Shailendra Kumar
Dhar Dwivedi, Hemant Kumar Bid, Rituraj Konwar, Geetika
Kharkwal, Vishal Chandra, Anila Dwivedi &
K. Hajela.Bioorganic & Medicinal Chemistry, 2009,
3847-3856. |
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Synthesis and Biological
Evaluation of Indolyl Bisphosphonates as Anti-bone Resorptive
and Antileishmanial Agents.Uma Sharan Singha , Ravi Shankara,Avinash
Kumarb, Ritu Trivedib,Naibedya Chattopadhyayb,Nishi Shakyac,
Shraddha Palnec, Suman Guptac & K Hajela .
Bioorganic & Medicinal Chemistry, 2008 ,
8482-8491. |
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Synthesis and Structure
Guided Evaluation of Estrogen Agonist and Antagonist Activities
of Some New Tetrazolyl Indole Derivatives:Uma Sharan Singh,
Ravi Shankar, Gaya P Yadav, Geetika Kharkwal, Anila Dwivedi,
Govind Keshri, M M Singh, P.R. Moulik & K.
Hajela.Eur. J. Medicinal Chemistry,2008,43, 2149-
2158. |
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"NAD+-dependent DNA
ligase (Rv3014c) from Mycobacterium tuberculosis: structure-function
relationship and identification of a specific inhibitor"
Srivatava,S.K.; Dube, D.; Kukshal,V.; Jha, Ashok. K.
Hajela, K.;Ramchandran. Proteins: Structure,
Function and Bioinformatics, 2007, 69, 97-111. |
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An efficient and improved
synthesis of 1,5-diketones : versatile conjugate addition
of nucleophiles to a , ß-unsaturated enones and
alkynones : Ravi shankar, Ashok K.Jha, Uma Sharan Singh
and K. Hajela. Tetrahedron Lett., 2006,
47, 3077-3079. |
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Synthesis and Biological
Activities of Some New Dibenzopyranones & Dibenzopyrans:
Search for Potential Estrogen Receptor Agonists and Antagonist.
Jaya Pandey, Ashok K. Jha, K. Hajela,
PSN Murthy, Shikha Sharma, Govind Keshri, Anila Dwivedi
and MM Singh; Bioorganic & Medicinal Chemistry,
12, (9),2239-50, 2004 |
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Facile synthesis of 2-arylbenzo[b]furans
through unusual acid catalysed 1,2- elimination. Ashok
K Jha, Pushkar C Sharma, Prakas R Maulik, Umesh Yadav
and K.Hajela. Indian J Chem. Vol. 43B,
1341-44, 2004. |
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