Brief Description of Process

Mefloquin hydrochloride is produced from alpha-picoline , ethyl triflouracetate, 2-amino benzotriflouride in 26-30%overall yeild. It is a broad spectrum antimalarial drug effective against all forms of malariaincluding chloroquin resistant strains.

Patent Filed

Industrial Classification

Pharmaceutical

Medical - Allopathic

Minimum Economic Size

Optimum Investment

Major Raw materials Required

10 Kg.

Not Available

alpha-picoline, trifluoro acetic acid, 2-amino benzo trifluoride

Status of Process

Major machinery used

Laboratory scale process

Glass lined reactor, autoclave, evaporator, liquid extractor, filter, crystalliser, dryer

Status (Prototype/Licensed)
No.of Licences

Year

Whether in production

One

1997

N.A.

Contact Person

Dr. S.Ray / Dr. D.P.Sahu
Chem. Tech. Div.,
Central Drug Research Institute, Lucknow