Dr. Prem Prakash Yadav
 
...



Scientist C
Medicinal and Process Chemistry Division
Central Drug Research Institute
Chattar Manzil Palace
Lucknow 226001, UP, India
 
Educational Qualifications M.Sc., Ph.D.
Phone No. +91-0522-2612411-18 Ext: 4437
Fax No. +91-0522-2623405, 2623938
E- mail pp_yadav@cdri.res.in , ppy_cdri@yahoo.co.in
Date of Birth 06.03.1978
 
RESEARCH EXPERIENCE
 
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Natural products and medicinal chemistry (10 years)
 
POST DOCTORAL RESEARCH
 
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Institute of Organic and Biomolecular Chemistry, Goettingen University, Germany with Prof. Hartmut Laatsch, funded by DAAD, Germany during 2008-2009.
 
POST DOCTORAL RESEARCH
 
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 Miss Ranjani Maurya (SRF, CSIR)
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 Mr. Makhtala Ravi (JRF,CSIR)
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 Mr. Anand Devireddy (JRF, CSIR)
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 Miss Parul Chauhan (PA, DST)
 
CURRENT AREAS OF INTEREST
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 Identification of novel/bioactive natural products from plants and microbial sources following dereplication strategies.
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Synthesis of bioactive molecules inspired from natural product scaffold.
SELECTED PUBLICATIONS
 
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 Muna Ali Abdalla, Prem P. Yadav, Birger Dittrich, Anja Schueffler, Hartmut Laatsch.“ent-Homoabyssomicins A and B, Two New Spirotetronate Metabolites from Streptomyces sp. Ank 210”. Organic Letters 2011, Article ASAP, DOI: 10.1021/ol103076y.
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 Prem P. Yadav, Vimal Nair, Birger Dittrich, Anja Schueffler, Hartmut Laatsch. “Lucknowlides A and B, tricyclic ketal-lactone metabolites from terrestrial Streptomyces Sp.” Organic Letters 2010, 12(17), 3800-3803.
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 Prem P. Yadav, Ranjani Maurya, Jayanta Sarkar, Ashish Arora, Sanjeev Kanojiya, Sudhir Sinha, M.N. Srivastava, Ram Raghubir. “Cassane Diterpenes from Caesalpinia bonduc” Phytochemistry 2009, 70, 256–261.
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 Kanojiyaa Sanjeev and Yadav Prem P - Fragmentation patterns of newly isolated cassane butenolide diterpenes and differentiation of stereoisomer by tandem mass spectrometry (2008) - J. Mass Spectrometry 43, 1413-1420
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 Yadav Prem P, Arora Ashish, Bid Hemant K, Konwar Ritu R and Kanojiya Sanjeev - New cassane butenolide hemiketal diterpenes from the marine creeper Caesalpinia bonduc and their antiproliferative activity. (2007) - Tetrahedron Letters 48, 7194-7198
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 Prem P. Yadav, Prasoon Gupta, A. K. Chaturvedi, P. K. Shukla, Rakesh Maurya. “Synthesis of 4-hydroxy-1-methylindole and benzo[b]thiophen-4-ol based unnatural flavonoids as new class of antimicrobial agents” Bioorganic and Medicinal Chemistry, 2005, 13, 1497-1505.
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 Prem P. Yadav, Ghufran Ahmad and Rakesh Maurya. An efficient route for commercially viable syntheses of furan- and thiophene-anellated ß- hydroxychalcones. Tetrahedron Letters, 2005, 46, 5621-5624.
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 R. Maurya, Prem P. Yadav. Furanoflavonoids: An Overview. Natural Product Reports 2005, 22(3), 400 - 424.
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 G. Ahmad, Prem P. Yadav, R. Maurya. Furanoflavonoid glycosides from Pongamia pinnata fruits. Phytochemistry, 2004, 65, 921-924.
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 Prem P. Yadav, G. Ahmad, R. Maurya. Furanoflavonoids from Pongamia pinnata fruits. Phytochemistry, 2004, 65, 439-443.