Dr PRABHAT RANJAN MISHRA
 
  Scientist C
Pharmceutics Division
Central Drug Research Institute
Lucknow 226001
Educational Qualifications M. Pharm., Ph.D
Date of Birth 2.12.1970
E Mail  prabhat_mishra@cdri.res.in , mishrapr[at]lycos dot com
 
RESEARCH EXPERIENCE
 
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Research Experience : As a scientist 'C' in Central Drug Research Institute
and Present position in Pharmaceutics Division since 04.09.2003 to till date.
Teaching/research Experience : Three years (Hamdard University, New-Delhi)
Industrial Experience : 1.5 years (Nicholas Piramal (I) Ltd.)

CURRENT AREAS OF RESEARCH
 
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 Layer-by-layer technology, Nanocrystal Technology, Ligand/receptor based targeting, coupling methods, Novel drug delivery approaches for various parasitic diseases and endocrine disorders including osteoporosis. Bioavailability improvement using nanoemulsion and nonionic surfactant based vesicles. Solubility enhancement of poorly water soluble CDRI candidate drugs.
 
RESEARCH GROUP
 
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 Girish Gupta (Research Associate, CSIR)
Vikas Jain (Senior Research Fellow, CSIR)
Deepak Singodia (Senior Research Fellow, ICMR)
Prashant Shukla (GATE-JRF, CSIR)
Ashwini Kumar (Project Assistant)
 
SELECTED PUBLICATIONS
 
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 P.R. Mishra, G.K. Gupta and V. Jain: Stearic acid and glyceryl monostearate based Self Assembled Vesicles: Preparation and In-vitro evaluation “J. Disp. Sci. Technol. 30 (9) (2009) (manuscript accepted)
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 Vikas Jain, B Nath, MA Siddiqui, PP Shah, A.B Pant and P.R. Mishra. galactosylated chylomicron mimicking emulsion for specific delivery of encapsulated taxol: an in vitro study “J. Pharm. Pharmacol” (2009) 61, 303-310
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 Prabhat R. Mishra, Loaye Al Shaal, Rainer H. Müller, Cornelia M. Keck Production and characterisation of Hesperetin nanosuspensions for dermal delivery. Int. J. Pharm (2009) 371, 182–189
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 Vikas Jain, V. Prasad, P. Jadhav and P.R Mishra. Preparation and Performance evaluation of saquinavir laden cationic miniemulsion. Drug Delivery 16(01), pp. 37 - 44. (2009).
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 Gupta Girish K, Jain Vikas and Mishra PR - Surface modified ultrathin polyelectrolyte nanoreservoir for delivery of proteins: Evaluation in terms of controlled release and biocompatibility (2008) - Nanotoxicology 2, S73
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 Jain Vikas, Gupta Girish K and Mishra PR - In-vitro inhibition of lipopolysaccharide induced mouse macrophage activation using surface modified lipid nanoemulsion (2008) - Nanotoxicology 2, S71
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 Prasad V, Kumar N and Mishra PR. - Amphiphilic gels as a potential carrier for topical drug delivery. (2007) - Drug Delivery 14, 75-85
BOOK CHAPTERS
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 Hydrogels based controlled delivery of therapeutic agents. In: Progress in Controlled and Novel Drug Delivery Systems. (Ed. N.K.Jain) Ist edition 341-360 (2004).
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 Biotinylated erythrocytes for specific delivery of drugs. In: Progress in Controlled and Novel Drug Delivery Systems. (Ed. N.K.Jain) Ist edition 248-258 (2004).
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 Provesicles as surrogate carrier for improved drug delivery. In: Progress in Controlled and Novel Drug Delivery Systems. (Ed. N.K.Jain) Ist edition 259-274 (2004).
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 Good Manufacturing and laboratory practices In: Pharmaceutical product Development. (Ed. N.K. Jain) Ist edition 468-502 (2005).
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 Pharmaceutical Validation In; Pharmaceutical product Development (Ed. N.K. Jain) Ist edition 503-528 (2005).
PATENTS
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 Patent Application No. 0842 DEL 2006 “Composition and methods of nonionic surfactant based vesicular formulation for improved delivery of cyclosporine”.
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 Patent Application No. 632/DEL/2009 Polymeric nanomatrix associated delivery
of Kaempferol in rats to improve its osteogenic action