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DR. RAM PRATAP |
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Sr.
Assistant Director
Medicinal and Process Chemistry Division
Central Drug Research Institute
Chattar Manzil Palace
Lucknow 226001, UP, India
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| Phone No. |
91-522-2212411-18, Extn.
4347 |
| Fax No. |
+91-0522-2243405, 2223938 |
| E- mail |
rpcdri[at]yahoo dot com
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| Educational Qualifications |
M. Sc., Ph. D. |
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| AWARDS |
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CDRI Technology Award 1994
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CDRI
Technology Award 1996 |
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CDRI
Incentive Award 2003 |
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| SIGNIFICANT
ACHIEVEMENTS |
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New antimalarial drug Bulaquine
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Novel hypolipidemic
drug 80/574 under phase III human trial |
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Highly efficient
process technology of Acyclovir transferred to Ranbaxy
Laboratories |
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Technology
for Primaquine Diphosphate transferred to Piramal Health
Care |
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Novel technology
for Quinidine transferred to Cinchona Department, Tamilnadu |
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| CURRENT
AREAS OF INTEREST |
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Synthesis
of Potential drugs in CNS and CVS area and novel technology
development for drugs |
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Synthesized
a close analogue of guggulsterone an active constituent
of Guggul, without drawbacks of guggulsterone, under phase
III clinical trial. |
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Currently
working on novel flavones, a potent antidiabetic compounds
selected for drug development. |
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Worked on
nucleosides and quinolines as potential antiparasitic
agents.
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| SELECTED
PUBLICATIONS |
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A method of
treating hyperlipidemic and hyperglycemic conditions in
mammals using pregnadienols and pregnadienones, US
Patent No. 6579862, 17th June, 2003 |
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Synthesis
and antihyperglycemic activity of chalcone based aryloxy
propanolamines, Bioorganic and Medicinal Chemistry,
2004, 12, 883-889 |
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Synthesis
and antiviral activity of 3-b-D-riboguranosyl-l,2,4-oxadiazole-carboxamide,
Nucleoside, Nucleotide and Nucleic acids, 2000,
19, 845 |
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A simple method
for synthesis of spongosine, azaspongosine and their antiplatelet
effects, Nucleosides and Nucleotides, 1995,
14, 1889 |
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