OBJECTIVE

• To design and synthesize novel molecules/isolate from natural sources and traditional remedies and bioevaluate them for generating new leads and to develop them as female and male contraceptives, spermicides with anti-HIV-STI properties and to understand the mode of action of promising agents to identify specific target sites to aid in the contraceptive development program.

• To design and synthesize novel molecules/isolate from natural sources and traditional remedies and bioevaluate them for generating new leads and to develop them as anti-osteoporosis agents using state-of-the-art in vitro cell-based screening methods as well as development of several animal models and to understand the mode of action of promising agents to identify specific target sites to aid in the anti-osteoporosis therapy development program. Identifying osteogenic/bone anabolic compounds/agents is a thrust area of research.

• To design and synthesize novel molecules/isolate from natural sources and bioevaluate them for development of promising agents for anti-cancer breast using cell-based and in vivo assays and to understand the mode of action of promising agents for therapeutic application. Identifying agents/compounds preventing/attenuating breast cancer metastasis to bone is considered a thrust area of research.

• To design and synthesize novel molecules/isolate from natural sources and traditional remedies and bio-evaluate them for development of promising agents for the treatment of benign prostatic hyperplasia and prostate cancer and to understand the mode of action of promising agents to identify specific target sites to aid in therapeutic development.