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SAFETY & CLINICAL DEVELOPMENT
Clinical & Experimental Medicine
 
CLINICAL TRIALS: EXPERIENCE AT CDRI, LUCKNOW
 
Compound
 
...Final Outcome
 
Centimizone (Anti-thyroid)
  Licensed for marketing
  Centbucridine (Local anaesthetic)   Licensed for marketing
  Centbutindole (Neuroleptic)   Licensed for marketing
  Gugulipid (Hypolipidaemic)   Licensed for marketing
  Centchroman (Oral contraceptive and DUB)   Licensed for marketing
  Centchroman (Anti-cancer (Breast)   Phase III
  Centpropazine (Anti-depressant)   Licensed for marketing
  Chandonium Iodide (Neuromuscular blocker)   Licensed for marketing
  Consap (Spermicidal cream)   Licensed for marketing
  Arteether ab (Anti-malarial)   Licensed for marketing Pediatric trials NDA submitted
  Compound 80/53 (Anti-malarial)   Licensed for marketing
  Mefloquine (Anti-malarial)   Phase I studies completed
  Fansimef (Anti-malarial)   Phase I/II studies completed
  Picroliv (Hepatoprotective)   Phase III trials completed
  Compound 80/574 (Hypolipidaemic)   Extended Phase III
  M. habana vaccine (Anti Leprosy)   Phase I/II completed
  CT-1 (Anti-diabetic)   Phase II completed
  Curcumin (Anti-inflammatory)   Phase II
  Centperazine (Anti-filarial)   Phase II
  Centazolone (Tranquilosedative)   Phase II dropped
  Garlic spray (Hypolipidaemic)   Phase II dropped
  Compound 73/602 (Anti-allergic)   Phase II - dropped
  Compound 81/470 (Anti-helminthic)   Phase II- dropped
  Centpiperalone (Hypoglycaemic)   Phase I dropped
  Centhaquine (Anti-hypertensive)
  Phase I dropped
  Centhaquine (Oral)   Phase I
  Centhaquine (Injectable)   dropped
  Coleonol (Anti-hypertensive)   Phase I dropped
  Cholera vaccine   Phase I dropped
  Centbutindole -Injectable (Neuroleptic)   Phase I- dropped
  Rifampicin- Injectable (Anti-tubercular)   Phase I- dropped
  Compound 82/437 (Anti-filarial)   Phase I - dropped
  Bacosides A&B (Nootropic)   Phase I completed
  CDRI34-D123 (Anti-diabetic)   Phase I completed
  Comp.99/373 (Anti-osteoporotic)   Phase I to be initiated
  Comp. 97/78 (Anti-malarial)   Phase I in progress
  CDR 134-F194 (Anti-diabetic)   IND submitted
  Comp. 99/411 (Anti-malarial)   IND to be filed
  Herbal medicament (Anti-stroke)   IND to be filed
  Cu-1/ 002 (PFO) (Hypolipidaemic)   IND to be filed.
 
Team members



 
 
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