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| Dr.
SANJAY BATRA |
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Medicinal Chemistry
Division
Central Drug Research Institute
PO Box 173,
Lucknow 226 001. |
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| Phone No. |
91-0522-2612411-18 Ext
4368 |
| Fax No. |
91-0522-2623405, 2623938 |
| E- mail |
s_batra@cdri.res.in |
| Educational Qualifications |
M.Sc, Ph.D |
| Date of Birth |
6th September 1965 |
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| POST
DOCTORAL EXPERIENCE |
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From University
of Mississippi, University MS 38677 USA during Nov. 2000-Nov.
2001 |
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| RESEARCH
INTEREST |
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Design and
Synthesis of antimalarial agents
• Search for
new scaffolds and pharmacophores
• Synthesis
of Hybrid compounds |
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Development of chemistry
associated with the Baylis-Hillman reaction
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Search for new fast reacting electrophiles
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Synthesis of novel synthetic intermediates
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Synthesis of heterocycles
-Aza-systems
-Drug scaffolds
-Natural products and natural product mimics |
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Catalytic hydrogenation
of 2-isoxazolines and isoxazoles |
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| HONORS
AND AWARDS |
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Fourth "Professor D.K. Banerjee Memorial Lecture Award" of the Department of Organic Chemistry, Indian Institute of Science, Bangalore (2011) |
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Bronze
medal of Chemical Research Society of India (2010-2011) |
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Most Cited paper
award from Tetrahedron for the block year 2006-2009 |
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Chief-Co-Editor for Anti-infective Agents: Medicinal Chemistry (Bentham
Publishers) |
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Awarded INSA travel
grant for 2008-2009 to visit UK |
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Council Member of the NOST, India
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Member of Governing Council of Chemical Research Society of India, Bangalore |
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| RESEARCH
STUDENTS |
| PhD Students |
| Dr. Amrendra K. Roy |
Senior Research Scientist |
Reddy’s Pharma,
Hyderabad |
| Dr. Richa Pathak |
DAAD-Fellow |
Prof. A. Marx (Konstanz Univ) |
| Dr. Vijay Singh |
PDF |
Prof. A. G. Hartig (Konstanz Univ) (2008-2011), Prof. Eric T. Kool (Stanford University, USA) (2011- ) |
| Mr. Sudharshan Madapa |
Research Scientist |
Aurigene, Bangalore |
| Mr. Somnath Nag |
Research Scientist |
Aurigene, Bangalore |
| Dr. Virender Singh |
Assistant Professor |
Punjab Central University, Bhatinda |
| Post Docs |
| Dr. Rashmi Saxena |
2003-2005 |
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| Dr. Zehra Tusi |
2006-2008 (under DST-WOS-A
scheme) |
| Present students |
| Ms. Amita Mishra |
SRF(CSIR) |
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| Mr. Samiran Hutait |
SRF(CSIR) |
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| Mr. Maloy Nayak |
SRF(CSIR) |
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| Mr. Subhendu Bhowmik |
SRF(CSIR) |
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Mr. Subhasish Biswas
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SRF(CSIR) |
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Ms. Garima Pandey
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JRF(UGC) |
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Mr. B. Harikrishna
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JRF(CSIR) |
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Mr. Shashikant Uttam Dighe |
JRF (CSIR) |
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| Instruction for
Students desirous of working with me |
Intake of PhD students in CSIR-CDRI will be on biannual basis through interview. However candidates with good academic track record can apply to me directly. All candidates applying to me should post their Biodata/ CV essentially with their recent photograph, a paragraph about motivation to do research and two letters of references. Preference shall be given to candidates a) with good academic record; b) have completed a project work (as part of their masters program) or have some experience in pharma/chemical industry and c) have good communication skills.
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| REVIEW
ARTICLES |
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Applications of allylamines for the syntheses of aza-heterocycles. S. Nag and Sanjay Batra Tetrahedron 2011, accepted. |
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1-Formyl-9H-β-Carboline: A Useful Scaffold for Synthesizing Substituted- and Fused β- Carbolines. V. Singh and Sanjay Batra. Curr. Org. Synth. 2011, in press. |
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Malaria and Leishmaniasis. Current Status of chemotherapy, New Leads and Targets for Drug Development. R. Pathak and Sanjay Batra AIA- Med. Chem. 2009, 226-267. |
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Advances in the synthesis of quinoline and quinoline-annulated ring systems. S. Madapa, Z. Tusi and Sanjay Batra Curr. Org. Chem. 2008, 12, 1116-1183. |
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Advances in the Baylis-Hillman Reaction-Assisted Synthesis of Cyclic Frameworks. V. Singh and Sanjay Batra Tetrahedron 2008, 64(20), 4511-4574. (Awarded most cited publication for the year 2006-2009 from TETRAHEDRON) |
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| SELECTED
PUBLICATIONS |
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Convenient synthesis of a library of lactam-fused b-carbolines via Ugi-reaction. S. Hutait, M. Nayak, A. Penta and Sanjay Batra Synthesis 2011, 419-430 |
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Copper-catalyzed cascade cyclization of 4-iodo-3-pyrazolecarbaldehyde with 1,2-phenylenediamines and 2-aminophenols. M. Nayak and Sanjay Batra Adv. Synth. Catal. 2010, 3431-3437. (highlighted in SYNFACTS 2011, 252). |
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Facile synthesis of dihydroquinoline-fused
canthines via intramolecular Aza-Diels-Alder reaction.
S. Hutait, V. Singh and Sanjay Batra
Eur. J. Org. Chem 2010, 6269-6276. |
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RCM-based approach to
7- and 8-member ring fused ?-carbolines. S. Hutait and
Sanjay Batra, Tetrahedron Lett. 2010,
51, 5781-5783. |
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Morita-Baylis-Hillman
of indole-2-carboxaldehyde: New vistas for indole-annulated
systems. S. Biswas, V. Singh and Sanjay Batra
Tetrahedron 2010, 66, 7781-7786. |
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Expeditious synthesis
of imidazole- and pyrrole-fused-benzodiazocines. A. Mishra
and Sanjay Batra Eur. J. Org. Chem. 2010,
4832-4840. |
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Application of primary
allyl amines from Morita-Baylis-Hillman adducts: Cyanogen-azide-mediated
synthesis of substituted 5-aminotetrazoles and their attempted
transformation to tetrazolo[1,5-a]pyrimidinones. S. Nag,
S. Bhowmik, H. M. Gauniyal and Sanjay Batra
Eur. J. Org. Chem. 2010, 4705-4702. |
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Utility of allyl azide
for the synthesis of annulated triazoles and tetrazoles.
A. Mishra, S. Hutait, S. Bhowmik, N. Rastogi, R. Roy and
Sanjay Batra Synthesis 2010,
2731-2748. |
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Advancing the Baylis-Hillman
chemistry of 1-formyl-?-carbolines for the synthesis of
indolizinoindole derivatives. V. Singh, S. Hutait, and
Sanjay Batra Eur. J. Org. Chem. 2010,
3684-3691. |
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Isonitriles from the
Baylis-Hillman adducts of acrylates: Viable precursor
to tetrazolo-fused diazepinones via post-Ugi cyclization.
M. Nayak and Sanjay Batra Tetrahedron
Lett. 2010, 51, 510-516. |
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Functional attenuation
of human sperm by novel, non-surfactant spermicides: precise
targeting of membrane physiology without affecting structure.
R. K. Jain, A. Jain, R. Kumar, V. Verma, J. P. Maikhuri,
V. L. Sharma, K. Mitra, Sanjay Batra,
and G. Gupta Human Reprod. 2010, 25,
1165-1176. |
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Versatility of substituted
1-formyl-9H-?-carbolines for the synthesis of new fused
?-carbolines via intramolecular 1,3-Dipolar Cycloaddition.
V. Singh, S. Hutait, S. Biswas and Sanjay Batra
Eur. J. Org. Chem. 2010, 531-539. |
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Baylis-Hillman reaction
of 1-formyl-?-carboline: one-step synthesis of the canthin-6-one
framework via an unprecedented cascade cyclization. V.Singh,
S. Hutait and Sanjay Batra Eur. J. Org.
Chem. 2009, 6211-6216. |
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First Copper-catalyzed
intramolecular amidation in substituted 4-iodopyrazoles
leading to the synthesis of pyrazolo[4,3-b]pyridine-5-ones.
S. Nag, M. Nayak and Sanjay Batra, Adv.
Synth. Catal. 2009, 351, 2715-2723. |
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Search for new pharmacophores
for antimalarial activity (Part III): Synthesis and bioevaluation
of new 6-thioureido-4-anilinoquinazolines. A. Mishra,
K. Srivastava, R. Tripathi, S. K. Puri, and Sanjay
Batra Eur. J. Med. Chem. 2009,
44, 4404-4412. |
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Synthesis of 2-amino-3,4-dihydroquinazolines
and imidazo[2,1-b]quinazoline-2-ones. A. Mishra and
Sanjay Batra Synthesis 2009,
3077-3088. |
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Stereoselective synthesis
of homoallyl nitroalkane derivatives via base-promoted
regioselective decarboxylation in Baylis-Hillman derivatives.
M. Nayak and Sanjay Batra Eur. J. Org.
Chem. 2009, 3505-3507. |
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Reductive-cyclization-mediated
syntheses of fused polycyclic quinolines from the Baylis-Hillman
adducts of acrylonitrile: Scope and limitations. V. Singh,
S. Hutait and Sanjay Batra Eur. J. Org.
Chem. 2009, 3454-3466. |
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