Dr. SANJAY BATRA
 
Medicinal & Process Chemistry Division
Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute,
BS-10/1, Sector 10, Jankipuram extension, Sitapur Road, PO Box 173,
Lucknow 226031, India.
 
Phone No. +91-522-2772450/2772550, Xtn- 4705/4706/4727/4732
Fax No. +91-522-2771941
E- mail batra_san@yahoo.co.uk, s_batra@cdri.res.in
Educational Qualifications M.Sc, Ph.D
Date of Birth

6th September 1965

 
POST DOCTORAL EXPERIENCE
From University of Mississippi, University MS 38677 USA during Nov. 2000-Nov. 2001
 
RESEARCH INTEREST

Design and Synthesis of antimalarial agents

  • Search for new scaffolds and pharmacophores
  • Synthesis of Hybrid compounds
  • Open Source programs

Development of chemistry associated with the Morita-Baylis-Hillman reaction

    • Search for new fast reacting electrophiles
    • Synthesis of novel synthetic intermediates
    • Synthesis of heterocycles
                             
                  -Aza-systems
                  -Drug scaffolds
                  -Natural products and natural product mimics

Transition-metal-based reactions

 
HONORS AND AWARDS

Fourth "Professor D.K. Banerjee Memorial Lecture Award" of the Department of Organic Chemistry, Indian Institute of Science, Bangalore (2011)

Bronze medal of Chemical Research Society of India (2010-2011)

Most Cited paper award from Tetrahedron for the block year 2006-2009

Co-Chief- Editor for Anti-infective Agents (Bentham Publishers)

Awarded INSA travel grant for 2008-2009 to visit UK

Council Member of the NOST, India

Member of Governing Council of Chemical Research Society of India, Bangalore

Member PAC, DST-SERB- Fast Track

 
RESEARCH STUDENTS

PhD Students

Dr. Amrendra K. Roy

Senior Research Scientist       

Reddy’s Pharma, Hyderabad

Dr. Richa Pathak

DAAD-Fellow  (2008-2011) 
Research Scientist                  

Prof. A. Marx (Konstanz Univ)
Theranos, California

Dr. Vijay Singh

PDF

Prof. A. G. Hartig (Konstanz Univ)  (2008-2011), Prof. Eric T. Kool (Stanford University, USA) (2011- )

Dr. Sudharshan Madapa        

Research Scientist

Aurigene, Bangalore

Dr. Somnath Nag                   
Research Scientist

Aurigene, Bangalore

Dr. Virender Singh                 Assistant Professor NIT, Jalandhar

Dr. Amita Mishra                   

Scientist  Polnox Corporation, USA 
Mr. Samiran Hutait Research Associate Dai-Ichi (Ranbaxy) Pharma, Delhi

Mr. Maloy Nayak

Research Associate Chembiotek, Pune

Post Docs

Dr. Rashmi Saxena

2003-2005

Dr. Zehra Tus

2006-2008 (under DST-WOS-A scheme)
Present Students
Mr. Subhendu Bhowmik SRF(CSIR)
Mr. Subhasish Biswas SRF (CSIR)
Ms. Garima Pandey SRF (UGC)
Mr. B. Harikrishna SRF (CSIR)
Mr. Shashikant Uttam Dighe SRF (CSIR)
Mr. Soumya Bhattacharya JRF (CSIR)

Ms. Veena Devi Yadav

JRF(CSIR)

 
Instruction for Students desirous of working in my research group
Intake of PhD students in CSIR-CDRI will be on biannual basis through interview. However candidates with good academic track record can apply to me directly. All candidates applying to me should post their Biodata/ CV essentially with their recent photograph, a paragraph about motivation to do research and two letters of references. Preference shall be given to candidates a) with good academic record; b) have completed a project work (as part of their masters program) or have some experience in pharma/chemical industry and c) have good communication skills.
Requirement- Two NET-qualified students for the Jan-2014 session
 
REVIEW ARTICLES
Thiourea and Guanidine derivatives as Antimalarial and Antimicrobial agents. A. Mishra and Sanjay Batra Curr. Top. Med. Chem. 2013 , 13(16), 2011-25.

1-Formyl-9H-β-Carboline: A Useful Scaffold for Synthesizing Substituted- and Fused β- Carbolines. V. Singh and Sanjay Batra. Curr. Org. Synth. 2012, 9, 513-52

Applications of allylamines for the syntheses of aza-heterocycles. S. Nag and Sanjay Batra Tetrahedron 2011, 67, 8959-9061.
Malaria and Leishmaniasis. Current Status of chemotherapy, New Leads and Targets for Drug Development. R. Pathak and Sanjay Batra AIA- Med. Chem. 2009, 226-267.
Advances in the synthesis of quinoline and quinoline-annulated ring systems. S. Madapa, Z. Tusi and Sanjay Batra Curr. Org. Chem. 2008, 12, 1116-1183.
Advances in the Baylis-Hillman Reaction-Assisted Synthesis of Cyclic Frameworks. V. Singh and Sanjay Batra Tetrahedron 2008, 64(20), 4511-4574. (Awarded most cited publication for the year 2006-2009 from TETRAHEDRON)
 
SELECTED PUBLICATIONS
Research Publications (Recent only)
Synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines via cascade imination/intramolecular decarboxylative coupling. G. Pandey, S. Bhowmik and Sanjay Batra Org. Lett..2013, on web 18 SEP.
http://pubs.acs.org/doi/full/10.1021/ol4023722
Iodine-mediated electrophilic tandem cyclization of 2-alkynylbenzaldehydes with anthranilic acid leading to 1,2-dihydroisoquinoline-fused benzoxazinones. S. U. Dighe and Sanjay Batra Tetrahedron.2013,on web 12 SEP, doi.org/10.1016/j.tet.2013.08.086.
Morita-Baylis-Hillman Approach toward Formal Total Synthesis of Tamiflu and Total Synthesis of Gabaculine. S. Bhowmik andSanjay Batra Eur. J. Org. Chem..2013,on web 13 SEP 2013, DOI: 10.1002/ejoc.201300977.
Divergent synthesis of allocolchicinoids via a triple cascade reaction and inhibition of insulin aggregation. S. Bhowmik, S. Khanna, K. Srivastava, M. Hasanain, J. Sarkar, S. Verma and Sanjay Batra ChemMedChem.2013,on web 5 SEP 2013, DOI: 10.1002/cmdc.201300302.
Substituent-guided switch between C-H activation and decarboxylative cross-coupling during Palladium/ Copper-catalyzed cascade reaction of 2-aminobenzoates with 2-haloarylaldehydes. S. Bhowmik, G. Pandey and Sanjay Batra Chem. Eur. J. 2013, 19, 10487-10491
Copper-catalysed synthesis of substituted isoindolo[2,1-a]quinoxalines and isoindolo[2,1-a]quinoxalin-6(5H)-ones. S. Biswas and Sanjay Batra Eur. J. Org. Chem. 2013, 4895-4902.
Synthesis of pyrazole-fused polycyclic systems from 4-iodopyrazolecarbaldehydes via intramolecular 1,3-dipolar cycloaddition reactions. M. Nayak, N. Rastogi and Sanjay Batra Tetrahedron. 2013, 69, 5029-5043
Expeditious synthesis of chiral 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazines. S. Bhowmick and Sanjay Batra Tetrahedron Lett. 2013, 54, 2251-2254
Iodine-mediated intramolecular electrophilic aromatic cyclization in allylamines: A general route to synthesis of quinolines, pyrazolo[4,3-b]pyridines and thieno[3,2-b]pyridines. H. Batchu, S. Bhattacharayya and Sanjay Batra Org. Lett. 2012, 14, 6330-6333
Copper-Catalyzed Multicomponent Coupling/Cycloisomerization reaction between substituted 1-formyl-9H-β-carbolines, secondary amines and substituted alkynes for the synthesis of substituted 3-amino-indolizino[8,7-b]indoles. S. U. Dighe, S. Hutait and Sanjay Batra ACS Combi. Sci. 2012, 14, 665-672
Enhancing the Reaction Rates of Morita-Baylis-Hillman Reaction  in Heterocyclic Aldehydes by Substitutions. Sooraj K, Sanjay Batra and N. Nair, ChemPhysChem 2012, 13, 3723-3730
Straightforward copper-catalyzed synthesis of pyrrolopyrazoles from halogenated pyrazolecarbaldehydes. M. Nayak, H. Batchu and Sanjay Batra Tetrahedron Lett. 2012, 53, 4206-4208
Synthesis of diverse fused-pyrazoles via Palladium-mediated heteroarylation of heteroarene C-H bond. M. Nayak and Sanjay Batra Eur. J. Org. Chem. 2012, 3677-3683.
One-step synthesis of 2-amino-5H-pyrimido[5,4-b]indoles, 2-(4,6-disubstituted-1,3,5-triazin-2-yl)-1H-indoles and 2,4,6-trisubstituted-1,3,5-triazines from substituted aldehydes. S. Biswas and Sanjay Batra Eur. J. Org. Chem. 2012, 3492-3499.
Versatile synthesis of 2-(substituted)phenyl-6,7-dihydro-1H-indol-4(5H)-ones from MBH acetates of 2-oxo-(substituted)phenylacetaldehydes. Harikrishna B. and Sanjay Batra, Eur. J. Org. Chem. 2012, 2935-2944.
Efficient synthesis of Maxonine analogues from N-substituted benzyl-1-formyl-9H-β-carbolines. S. Hutait, S. Biswas and Sanjay Batra, Eur. J. Org. Chem. 2012, 2453-2462.
Synthesis of substituted pyrazolo[4,3-b]pyridines via Copper-mediated intramolecular C-N cross-coupling in the primary allylamines. M. Nayak and Sanjay Batra RSC Adv. 2012, 3367-3373.
2-(N-allylaminomethyl)cinnamaldehydes as substrates for syntheses of aza-polycycles via intramolecular Cycloaddition reactions. A. Mishra, N. Rastogi and Sanjay Batra, Tetrahedron 2012, 68, 2146-2154.
Copper-Catalyzed Cascade Reaction of 4-Iodopyrazole derivatives with amidines for the synthesis of of substituted pyrazolo[4,3-d]pyrimidines and pyrazolo[4,3-d]pyrimidin-7(6H)-ones. M. Nayak, N. Rastogi and Sanjay Batra, Eur. J. Org. Chem. 2012, 1360-1366.