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| Dr.
SHAILJA BHATTACHARYA (NEE MISRA) |
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Scientist F
Division of Parasitology,
Central Drug Research Institute,
Post Box 173, Lucknow (U.P.) - 226001, India |
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| Fax No. |
+ 91 - 0522 - 2223938
/ 2223405 |
| E-Mail |
shailjacdri[at]yahoo dot com |
| Educational Qualifications |
M.Sc. (Zoology), Ph.D. |
| Date of Birth |
19.03.1956
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| POST
DOCTORAL RESEARCH |
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Institute
for Tropical Hygiene, Heidelberg, Germany, 1987-1989
Identification and purification of an immunodominant antigen
of filarial parasite A. viteae using immunological and molecular
biology techniques. |
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Institute for Parasitology, Giessen, Germany, Sept.-December,
1997
Molecular cloning of sheath proteins of filarial parasite L.
carinii.
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| RESEARCH
EXPERIENCE |
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27 years
research experience on development of in vitro and in
vivo models, molecular and immunobiological studies including
characterization and purification of protective and diagnostic
filarial antigens, development of antifilarial agents
from natural and synthetic source |
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| CURRENT
AREAS OF INTEREST |
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· Immunobiology, chemotherapy and molecular
biology of filarial parasites
- Development macrofilaricide from natural products
- Development of models and studies on host-parasite
interactions in B. malayi mouse model
- Identification and molecular characterization of immunodominant
antigens of filariids
- Evaluation of immunomodulatory activity in plant products
and use of immunomodulators alone or as an adjunct to
chemotherapy
- Role of endosymbiont bacteria Wolbachia in filarial
host-parasite interactions.
- Effector cell function in imparting resistance to
filarial infection.
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D GUIDANCE TO STUDENTS |
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Four students have been awarded PhD degree:
Ms. Manisha Dikshit
Ms. Monisha Mukherjee
Ms. Usha Singh
Ms. Ruma Gupta
PhD thesis work of following students is underway:
Ms. Preeti Bajpai
Mr. Shailendra Kumar Verma
Mr. Satish Vedi
Mr. Anil Dangi
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| SELECTED
PUBLICATIONS |
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Macrophages
in the development of protective immunity against experimental
Brugia malayi infection. Ruma Gupta, P. Bajpai,
L. M. Tripathi, V. M. L. Srivastava, S. K. Jain and Shailja
Misra-Bhattacharya, Parasitology (2004)
129 (3) 1-13. |
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4-Methyl-7-(tetradecanoyl)-2H-1-benzopyran-2-one:
A novel DNA topoisomerase II inhibitor with adulticidal
and embryo static activity against sub periodic Brugia
malayi. Shailja Misra-Bhattacharya, Diksha
Katiyar, Preeti Bajpai; R. P. Tripathi & J. K. Saxena.
Parasitology Res., 92 (3) 177-182, Feb. 2004. |
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Immunomodulator
tuftsin augments antifilarial activity of Diethylcarbamazine
against experimental Brugian filariasis. Owais, M., Misra-Bhattacharya,
S., Haq, W., Gupta, C. M. J. Drug Targ. (2003)
11 (4) 247-251 |
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Brugia
malayi: Establishment in inbred and outbred strains
of mice. Ruma Gupta, K. Tyagi, S. K. Jain & Shailja
Misra-Bhattacharya. Experimental Parasitology,
103, (issue 1-2) 57-60 (2003). |
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Immunomodulatory
effect of Albizzia lebbeck. C. C. Barua, P. P.
Gupta, G. K. Patnaik, Shailja Bhattacharya, R.
K. Goel, D. K. Kulshrestha, M.P. Dubey & B.N. Dhawan.
Pharmaceutical Biology, 38, 1-5 (2000). |
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Experimental
transmission of nocturnally periodic Wuchereria bancrofti
to Indian leaf monkey (Presbytis entellus). S. Misra,
K. Tyagi & R.K. Chatterjee. Experimental Parasitology.
86, 155-157 (1997). |
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