Dr. Mohammad Imran Siddiqi
  Scientist -C
Computational Biology & Bioinformatics Group
Molecular and Structural Biology Division
Central Drug Research Institute
Lucknow- 226001
U.P., India
 
Educational Qualifications M.Sc. (Biophysics) A.I.I.M.S., New Delhi
Ph.D. (Biophysics) A.I.I.M.S., New Delhi
Telephone +91 522 2612411 extn- 4468
Fax +91 522 2623405
E- Mail imsiddiqi@yahoo.com
 
POST-DOCTORAL RESEARCH
 
•
 University of Wuerzburg, Germany (August, 2000- Januay,2003)
•
 Biotechnology Research Institute, Montreal , NRC Canada (Feb, 2003- March,2004)
CURRENT RESEARCH AREAS
 
•
 Informatics: Bio-informatics and Cheminformatics
•
 Computational Structural biology: Biomolecular engineering & Modeling, Computer-Aided Molecular Design and Simulation.
•
 Rational Drug design: Virtual screening, de novo design, pharmacophore perception, SAR and ADME, Molecular docking, Conformational Analysis, Binding free energy simulations and Protein Ligand interactions.
 
SELECTED PUBLICATIONS
 
•
 Synthesis, Molecular Docking and PTP1B Inhibitory Activity of Functionalized 4,5-Dihydronaphthofurans and Dibenzofurans, Dixit, M., Saeed, U., Kumar, A., Siddiqi, M.I., Tamrakar, A.K., Srivastava, A.K. and Goel, A. Medicinal Chemistry, 2007 (in press)
•
 Raghu Ram, EVS, Kumar, A., Biswas, S., Kumar, A., Chaubey, S., Siddiqi, M.I. and Habib, S. (2007) Nuclear gyrB encodes a functional subunit of the Plasmodium falciparum gyrase that is involved in apicoplast DNA replication. Mol Biochem. Parasit. 154, 30-39.
•
 Agrawal, H., Kumar, A., Bal, N.C., Siddiqi M.I., and Arora, A. (2007) Ligand based Virtual Screening and Biological Evaluation of Inhibitors of Chorismate Mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv., Bioorg. Med. Chem. Letts. 17(11), 3053-3058.
•
 Mishra, J.K., Garg, P., Doohare, P., Kumar, A., Siddiqi, M.I. Ray, M. and Panda, G. (2007) Amino acid based enantiomerically pure 3-substituted benzodiazepine-ones : a new class of anti-ischemic agents. Bioorg Med Chem Lett. 17(5), 1326-1331.
•
 Naim, M., Bhat, Sathesh, Rankin; K. N., Dennis, S., Chowdhury, S. F., Siddiqi, M. I., Drabik, P., Sulea T., Bayly, C., Jakalian, A. and Purisima, E.O. (2007) Solvated interaction energy (SIE) for scoring protein-ligand binding affinities. 1. Exploring the parameter space. J. Chem. Info. and model. 47(1), 122-133.
•
 Rawal, R.K., kumar, A., Siddiqi, M. I. and Katti, S.B. (2007) Molecular Docking Studies on 4-Thiazolidinones as HIV-1 RT Inhibitors, J Mol Model, 13(1), 155-61.
•
 Shagufta, Ashutosh Kumar, Gautam Panda and Siddiqi, M.I. (2007), CoMFA and CoMSIA based 3D-QSAR Analysis of Diaryloxy methano phenanthrene Analogues as Anti-tuberculosis Agents. J Mol Model. 13(1), 99-109.
•
 Kumar, A., Saeed, U. and Siddiqi, M.I. (2006) Molecular Docking and 3-D QSAR Studies of Human Mitotic Kinesin Eg5 Inhibitors. Med. Chem. Res. 15 (1/6), 243.