Dr. Md. Sohail Akhtar
 
 

Scientist Gr IV
Molecular and Structural Biology Division
 
Educational Qualifications M.Sc. (Calicut) Ph.D (JNU)
E Mail mdsohailakhtar@yahoo.com
RESEARCH AREAS
 
•
 Molecular Biophysics / Protein Folding
 
HONOURS & AWARDS
•
 CSIR Young Scientist Award-2006
•
 National Academy of Sciences, India, Young Scientist Award-2006
 
 
SELECTED PUBLICATIONS
 
•
 Akhtar. Md. S. and Bhakuni V. (2007) Role of ionic interactions and linker in the domain interaction and modulation of functional activity of hyaluronate lyase. Biochem. Biophys. Res. Commun. In press
•
 Akhtar. Md. S., Krishnan, MY. and Bhakuni V. (2006) Insight into the mechanism of action of hyaluronate lyase; role of C-terminal domain and Ca2+ in the functional regulation of enzyme. J. Biol. Chem., 281, 28336-28344
•
 Mishra P., Akhtar, Md. S. and Bhakuni V. (2006) Unusual structural features of the bacteriophage-associated hyaluronate lyase (HylP2). J. Biol. Chem., 281, 7143-7150
•
 Akhtar. Md. S. and Bhakuni. V. (2004) Streptococcus pneumoniae hyaluronate lyase: an overview. Current Science. 86, 285-295.
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 Akhtar. Md. S. and Bhakuni. V. (2003) Streptococcus pneumoniae hyaluronate lyase contains two non-cooperative independent folding/unfolding structural domains: characterization of functional domain and inhibitors of enzyme. J. Biol. Chem., 278, 25509-25516
•
 Akhtar. Md. S. and Bhakuni. V. (2003) Alkaline treatment has contrasting effects on the structure of deglycosylated and glycosylated forms of glucose oxidase. Arch. Biochem. Biophys., 413, 221-228
•
 Akhtar. Md. S., Ahmad, A. and Bhakuni. V. (2002) Divalent cation induced changes in structural properties of the dimeric enzyme glucose oxidase: Dual effect of dimer stabilization and dissociation with loss of cooperative interactions in enzyme monomer. Biochemistry, 41, 7142-7149
•
 Akhtar. Md. S., Ahmad, A. and Bhakuni. V. (2002) Guanidinium chloride- and urea-induced unfolding of the dimeric enzyme glucose oxidase. Biochemistry, 41, 3819-3827.
•
 Ahmad, A. Akhtar. Md. S., and Bhakuni. V. (2002) Monovalent cation-induced conformational change in glucose oxidase leading to stabilization of the enzyme. Biochemistry, 40, 1945-1955.