DR. T. NARENDER
  Scientist-C
Medicinal and Process Chemistry Division,
Central Drug Research Institute,
Lucknow-226 001 (U.P), India
 
 
Educational Qualifications M Sc., B Ed., Ph.D.
Phone No. +90-0522-2212411-17 Ext: 4440
Fax No. +90-0522-2623405, 2623938
E-Mail

tnarender@rediffmail.com

 
RESEARCH EXPERIENCE
 
Natural Products (5 years), Marine Natural Products (2 years) and Endocrinology (1 year)
 
CURRENT AREAS OF INTEREST
 
Development of drug/lead from the medicinal plants and marine organisms and synthesis of bioactive compounds.
SELECTED PUBLICATIONS
 
Total synthesis of Munchiwarin, A triprenylated chalcone from Crotalaria medicagenia. T. Narender, K. Papi Reddy, Shweta, K. Srivastava, D.K.Mishra and S.K.Puri. Organic Letters 2007, 9, 5369-5372.
Antihyperglycemic and antidyslipidemic agent from Aegle marmelos. T. Narender, S. Shweta, P. Tiwari, K. Papi Reddy, T. Khaliq, P. Prathipati, A. Puri, A.K. Srivastava, R. Chander, S.C. Agarwal and K. Raj. Bioorganic & Medicinal Chemistry Letters 2007, 17, 1808-1811.
Highly efficient and regioselective synthesis of keto-enamine Schiff bases of 7-hydroxy-4-methyl-2-oxo-2H-benzo[h]chromene-8,10-dicarbaldehyde and 1-hydroxynaphthalene-2,4-dicarbaldehyde. Koneni V. Sashidhara,* Jammikuntla N. Rosaiah and Tadigoppula Narender.* Tetrahedron Letters 2007, 48, 1699-1702.
A simple and highly efficient method for the synthesis of chalcones by using Borontrifluoride-etherate. T. Narender* and K. Papi Reddy. Tetrahedron Letters 2007, 48, 3177-3180.
BF3–Et2O mediated biogenetic type synthesis of chromanochalcones from prenylated chalcones via a regioselective cyclization reaction. T. Narender* and K. Papi Reddy. Tetrahedron Letters 2007, 48, 7628-7632.
Naturally occurring Uracil dimer from the Marine sea hare Dolabella auricularia. T. Narender,* T. Khaliq and M. N. Srivastava. Natural Products Communications 2007, 2, 71-73.
Occurrence, Biosynthesis, Biological activity and NMR Spectroscopy of D and B, D Ring Seco-limonoids of Meliaceae Family. T. Narender,* T. Khaliq, Shweta, K. Papi Reddy, R. K. Sharma. Natural Products Communication 2007, 2, 203-221 (review article).
A novel lupane class of triterpenoid from Peganum harmala. T. Narender,* T. Khaliq. Natural Products Communications 2007, 2, 1079-1081.
Antidyslipidemic activity of Indigofera tinctoria. Anju Puri, Tanvir Khaliq, Rashmi Saxena, Geetica Bhatia, Ramesh Chander, Tadigoppula Narender.*J. Herbal Pharmacotherapy 2007, 7, 57-64.
Allium sativum constituents: Effect on free radical generation from rat neutrophils. A. Sankarnarayanan, T. Narender, S. Kumar, M. Dikshit.* Cellular and Molecular Biology 2007, 53, 63-67
Xyloccensin X and Y, Two New Limonoids from Xylocarpus molluccensis: NMR Investigation in Mixture. Abhijeet Deb Roya, Rajesh Kumar, Poonam Gupta, Tanvir Khaliq, T. Narender, Vijailakshmi and Raja Roy 2006. Magnetic Resonance in Chemistry, 44, 1054-1057.
Antidyslipidemic activity of Furano Flavonoids isolated from Indigofera tinctoria. T. Narender, T. Khaliq, A. Puri, R. Chander, 2006. Bio-org. Med. Chem. Lett., 16, 3422-3414.
4-Hydorxyisoleucine an unusual Amino acid as Antidyslipidemic and Antihyperglycemic agent. T. Narender, Anju Puri, Shweta, Tanvir Khaliq, Rashmi Saxena, Geetica Bhatia and Ramesh Chander, 2006. Bio-org. Med. Chem. Lett. 16, 293-296.
Synthesis of Chromenochalcones and Evaluation of their in-vitro Antileishmanial activity. T.Narender, K. Tanvir,. Shweta., Nishi. N.Goel, S. Gupta, 2005. Bio-org. Med. Chem. 13, 6543-6550
Prenylated Chalcones isolated from Crotalaria genus inhibits in-vitro growth of the human malaria parasite Plasmodium falciparum T. Narender, Shweta, K.Tanvir, M.Srinivasa Rao, K.Srivastava and S.K.Puri.2005, Bioorg. Med. Chem. Lett., . 15, 2453-2455
A Convenient and Biogenetic type Synthesis of few naturally occurring Chromenodihydrochalcones and their in-vitro antileishmanial activity T. Narender, Shweta and S.Gupta 2004. Bioorg. Med. Chem. Lett., 14, 3913-3916.
Neoadifoline a New Indole Alkaloid from the Adina cardifolia, B.Balazs, G. Toth, P.S.Rao, T. Narender, N.Subbarao, Gy.Howarth and H.Duddeck., 1999. Magn. Res. Chem., 37, 751-753.
Further dihydro chalcones from the Crotalaria ramosissima, J.K.Kumar, T. Narender, M.S.Rao, P.S.Rao, G.Toth, B.Balazs and H.Duddeck,1999. J. Braz. Chem. Soc., 10, 278-280