DR. . YENAMANDRA S. PRABHAKAR
 
...
 Medicinal Chemistry Division
Central Drug Research Institute
Lucknow - 226 001, INDIA.
 
Phone No. +91-0522-2212411-18 (7 lines), Ext. 4385 (lab)
Fax No. +91-0522-2243405, 2223938
E- mail yenpra[at]yahoo dot com
Educational qualifications M.Sc. (A.U., Visakhapatnam), Ph.D. (B.I.T.S., Pilani).
Date of Birth

10-8-1959
 
 
RESEARCH INTERESTS AND EXPERTISE
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 Theoretical aspects of drug design and modeling of compounds of biological interest;
Physicochemical aspects of organic compounds;
Theoretical organic chemistry;
Software development for chemistry and drug research;
Informatics.
SELECTED PUBLICATIONS
 
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 Gupta MK and Prabhakar YS - QSAR Study on Tetrahydroquinoline Analogues as Plasmodium Protein Farnesyltransferase Inhibitors: A Comparison of Rationales of Malarial and Mammalian Enzyme Inhibitory Activities for Selectivity (2008) - Eur. J. Med. Chem. 43, 2751-2767
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 Prabhakar YS and Gupta MK - Chemical Structure Indices in In Silico (2008) - Molecular Design, Sci Pharm. 76, 101-132
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 Sharma S, Prabhakar YS, Singh P and Sharma BK. - QSAR study about ATP-sensitive potassium channel activation of cromakalim analogues using CP-MLR approach (2008) - Eur. J. Med. Chem. 43, 2354-2360
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 Singh S, Soni LK, Gupta MK, Prabhakar YS and Kaskhedikar SG - QSAR studies on benzoylaminobenzoic acid derivatives as (2008) - Eur. J. Med. Chem. 43, 1071-1080
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 Rawal RK, Prabhakar YS and Katti SB - Molecular surface features in modeling the HIV-1 RT inhibitory activity of 2-(2,6-disubstituted phenyl)-3-(substituted pyrimidin-2-yl)-thiazolidin-4-ones. (2007) - QSAR & Combinatorial Science 26, 398-406
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 Saquib M, Gupta MK, Sagar R, Prabhakar YS, Shaw AK, Kumar R, Maulik PR, Gaikwad AN, Sinha S, Srivastava AK, Chaturvedi V, Srivastava R and Srivastava BS - C-3 alkyl/arylalkyl-2,3-dideoxy hex-2-enopyranosides as antitubercular agents: Synthesis, biological evaluation, and QSAR study. (2007) - Journal of Medicinal Chemistry 50, 2942-2950
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 Gupta, Manish K; Prabhakar, Yenamandra S - Topological descriptors in modeling the antimalarial activity of 4-(3',5'-disubstituted anilino)quinolines (2006) - Journal Of Chemical Information And Modeling, 46, 93-102.
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 Prabhakar, Yenamandra S; Balasubramanian, Krishnan - A simple algorithm for unique representation of chemical structures-cyclic/acyclic functionalized achiral molecules (2006) - Journal Of Chemical Information And Modeling, 46, 52-56.
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 Prabhakar, Yenamandra S; Gupta, Manish K; Roy, Nobendu; Venkateswarlu, Yenamandra - A high dimensional QSAR study on the aldose reductase inhibitory activity of some flavones: topological descriptors in modeling the activity (2006) - Journal Of Chemical Information And Modeling, 46, 86-92.
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 A Combinatorial Approach to the Variable Selection in Multiple Linear Regression: Analysis of Selwood et al Data Set - A Case Study. Y.S. Prabhakar. QSAR and Combinatorial Science, 2003, 22, 583-595.
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 Synthesis and QSAR Studies on the Antifungal Activity of 2,3,4-Substituted Thiazolidines. Y.S. Prabhakar, P. Jain, Z.K. Khan, W. Haq and S.B. Katti. QSAR and Combinatorial Science, 2003, 22, 456-465.
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 Analysis of Tetrahedral Carbon in QSAR Studies. A Case Study Using HMGR Inhibitors. Y.S. Prabhakar. J. Chem. Inf. Comp. Sciences, 1999, 39, 650-653.
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 A theoretical study of hydrophobic fragment and factor constants of Hansch and Leo: Estimation of a few non-available fragments and factors. Y.S. Prabhakar, Ind. J.Biochem. Biophys., 1996, 33, 72-75.

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 A model to quantify disease state based on the ayurvedic concept of tridosa. Y.S. Prabhakar and D.S. Kumar. Bull. Ind. Inst. Hist. Med., 1993, 23, 1-19.