DR.  KISHOR MOHANAN
 
..

Senior Scientist
Medicinal and Process Chemistry Division
Central Drug Research Institute
Lucknow-226031, India
 
Educational Qualifications

Ph.D.: CSIR-National Institute for Interdisciplinary Science and Technology (formerly RRL), Trivandrum, Kerala (2007), Mentor: Dr. G. Vijay Nair,
M.Sc.:  Mahatma Gandhi University, Kottayam, Kerala (2001)
Date of Birth 10.03.1979
Phone 05222772450Ext. 4687 (Off.) & 4678 (Lab)
E-Mail

[email protected] , [email protected]
 
AWARDS
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 Welcome Scholarship from the City of Marseille (2010), France
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 Fellowship of the National Science Council (2007), Taiwan
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 CSIR Junior Research Fellowship (2002), India
 
CURRENT AREAS OF INTEREST
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 Asymmetric domino-multicomponent reactions
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Organocatalysis
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 New strategies for the synthesis of medicinally active heterocycles
 
CURRENT PROJECTS
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 ‘Development of Catalytic Asymmetric Fluorination and Fluorocyclization Reactions’ under DST-Start-up Research Grants (Young Scientists) Scheme (2014-2017)
 
PROFESSIONAL EXPERIENCE
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 May, 2013-present, Senior Scientist, Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India
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 2009-2012,Post-doctoral fellow, Aix-Marseille University, Marseille, France, Mentor: Prof. Jean Rodriguez
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 2008-2009, Post-doctoral fellow,University of Montpellier, Montpellier, France, Mentor: Dr. Michael Smietana
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 2007-2008,Post-doctoral fellow,National Tsing-Hua University, Hsinchu, Taiwan, Mentor:Prof. Biing.-JiunUang
 
RESEARCH GROUP
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 Raju Arora (Technical Assistant)
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 Ashis Kumar Gupta (SRF)
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 Shakir Ahamad (SRF)
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 Ekta Gupta (JRF)
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 Narendra Kumar Vaishanv (JRF)
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 Mohd Khalid Zaheer (JRF)
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 Rajesh Patidar (NIPER M. Pharm.)
 
LIST OF PUBLICATIONS
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 Substrate-controlled product-selectivity in the reaction of Bestmann-Ohira reagent with N-unprotected isatin-derived olefins. Gupta, A. K.; Ahamad, S.; Gupta, E.; Kant, R.; K. Mohanan, K. Org. Biomol. Chem., 2015, 13, 9783
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 Domino Reaction Involving the Bestmann-Ohira Reagent and ,-Unsaturated Aldehydes: Efficient Synthesis of Functionalized Pyrazoles. Ahamad, S.; Gupta, A. K.; Kant, R.; Mohanan, K. Org. Biomol. Chem., 2015, 13, 1492
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 Practical and efficient organocatalytic enantioselective α-hydroxyamination reactions of β-ketoamides. Mailhol, D.; Castillo, J. C.; Mohanan, K.; Coquerel, Y.; Rodriguez, J. ChemCatChem2013, 5,1192
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 Transition-metal-free α-arylation of β-ketoamides via an interrupted insertion reaction of arynes.  Mohanan K.; Coquerel, Y.; Rodriguez, J. Org. Lett. 2012, 14, 4686
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 Catalyst- and halogen-free regioselective Friedel-Crafts-type α-ketoacylations. Mohanan K.; Presset, M.; Mailhol, D.; Coquerel, Y.; Rodriguez, J. Chem. Eur. J.2012, 18, 9217
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 1,3-Dipolar cycloaddition of hydrazones with α-oxo-ketenes: a three-component stereoselective entry to pyrazolidinones and an original Class of Spirooxindoles. Presset, M.; Mohanan, K.; Hamann, M.; Coquerel, Y.; Rodriguez, J. Org. Lett. 2011, 13, 4124
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 Bestmann-Ohira-based three-component regioselective synthesis of 3-carbo-5-phosponyl pyrazoles via a Claisen–Schmidt/1,3-dipolar cycloaddition/oxidation reaction sequence.Martin, A. R.; Mohanan, K.; Toupet, L.; Smietana, M.; Vasseur, J.–J. Eur. J. Org. Chem. 2011,  3184
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 Three component reaction using the Bestmann-Ohira reagent: A regioselective synthesis of phosphonyl pyrazole rings. Mohanan, K.; Martin, A. R.; Toupet, L.; Smietana, M.; Vasseur, J.–J. Angew. Chem. Int. Ed., 2010, 49, 3196. [This work has been highlighted in Synfacts2010, 7, 757 and Synform (Synstories, 2010/8, A66)]
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 Expanding the borononucleotide family: Synthesis of boronoanalogues of dCMP, dGMP and dAMP. Martin A. R.; Mohanan, K.;Luvino, D.; Floquet, N.; Baraguey, C.; Smietana, M.; Vasseur, J.-J. Org. Biomol. Chem., 2009, 7, 4369. (Accepted as a hot article with inside cover page)
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 Stereoselective synthesis of 3,4-trans-disubstituted γ-lactams by cerium(IV) ammonium nitrate mediated radical cyclization of cinnamamides. Nair, V.; Mohanan, K.; Suja, T. D.; Biju, A. T. Synthesis2007, 1179
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 Novel synthesis of highly functionalized pyrazolines and pyrazoles by triphenylphosphine mediated reaction of dialkyl azodicarboxylate with allenic esters. Nair, V.; Biju, A. T.; Mohanan, K.; Suresh, E. Org. Lett. 2006, 8, 2213
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 A convenient synthesis of 2,2-diaryl cyclobutanones by cerium(IV) ammonium nitrate (CAN) mediated oxidation of methylenecyclopropanes (MCPs). Nair, V.; Suja, T.D.; Mohanan, K . Synthesis2006, 2531
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 CAN mediated oxidative addition of 1,3-dicarbonyl compounds to methylenecyclopropanes: A facile synthesis of spirocyclopropyl dihydrofurans. Nair, V.; Suja, T.D. ; Mohanan, K. Synthesis2006, 2335
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 Stereoselective synthesis of 3,4-trans-disubstituted pyrrolidines and cyclopentanes via intramolecular radical cyclizations mediated by CAN. Nair, V.; Mohanan, K.; Suja, T.D.; Suresh, E. Tetrahedron Lett. 2006, 47, 2803
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 CAN mediated stereoselective cyclisation of epoxypropyl cinnamyl amines to 3, 4, 5- trisubstituted piperidines and supramolecular assembly of the latter aided by ethyl acetate.  Nair, V.; Mohanan, K.; Suja, T.D.; Suresh, E. Tetrahedron Lett. 2006, 47, 705
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 A convenient protocol for C-H oxidation mediated by an azido radical culminating in Ritter-type amidation.  Nair, V.; Suja T.D.; Mohanan, K. Tetrahedron Lett. 2005, 46, 3217
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 A mild and efficient procedure for the preparation of dimethyl and diallylacetals of aromatic aldehydes mediated by cerium(IV) ammonium nitrate. Nair,V.; Rajan, R.; Balagopal, L.; Nair, L. G.; Ros, S.; Mohanan, K. Ind. J. Chem.2005, 45B, 141
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 CAN mediated cyclization of epoxypropylcinnamyl ethers; a facile stereoselective synthesis of tetrahydropyran derivative. Nair, V.; Balagopal, L.; Rajan, R.; AniDeepthi.;Mohanan, K.; Rath, N. P. Tetrahedron Lett. 2004, 45, 2413
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 Ce(IV) ammonium nitrate mediated oxidative rearrangement of cyclobutanes and oxetanes. Nair,V.; Rajan, R.; Mohanan, K.; Sheeba,V. Tetrahedron Lett. 2003, 44, 4585