DR. MADDI SRIDHAR REDDY
 
...



Senior Scientist (CSIR-CDRI)/Assistant Professor (AcSIR)
(Since December 2010)
Medicinal & Process Chemistry Division
CSN-205, CSIR-Central Drug Research Institute
B.S.10/1, Sector-10, Jankipuram Extension
Lucknow 226 031. India.
Google Scholar link: http://scholar.google.co.in/citations?user=CDU3jBMAAAAJ&hl;=en

 
Phone No. 522-2612411-18 (4757) , Mobile: 91-7897582222.
E- mail [email protected]
[email protected]
Educational Qualifications M.Sc., Ph.D.
Date of Birth 25-02-1978
 
EDUCATION AND AWARDS
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 Post-Doctoral Research
 
  • Prof. Pierre Deslongchamps’ Laboratory, Department of Chemistry University of Sherbrooke, Sherbrooke, Quebec, Canada- Mar 2007- Jan 2009
  • Prof. Pierre Deslongchamps’ Laboratory, Omega Chem Labs, Levis, Quebec, Canada-Jan 2009-Dec 2010.
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 Doctor of Philosophy (Chemistry) : Doctoral Research was carried out at Indian Institute of Chemical Technology, Hyderabad, India, 2001- 2006. Degree (2007) from Osmania University
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Master of Science (Organic Chemistry): Osmania University, Hyderabad, Andhra Pradesh, India, 1998-2000
 
RESEARCH GROUP
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    		 Yalla Kiran Kumar (JRF) (Graduate Student)
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    		 Nuligonda Thirupathi (JRF)  (Graduate Student)
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    		 Madala Hari Babu (JRF) (Graduate Student)
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    		 Surendra Puri (JRF) (Graduate Student)
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    		  Gadi Ranjit Kumar (JRF) (Graduate Student)
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    		  Vikas Dwivedi (JRF) (Graduate Student)
    •
    		  Manda Rajesh
    •
    		  Vaishya Pooja (M. Sc. Program)
     
    RESEARCH AREAS
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    		 Organo- and Metallo Catalysis, Asymmetric Synthesis and Applications in Medicinal Chemistry
     
     
    CURRENT PROJECTS
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    "Probing Electrophilic Cyclization of Alkynols and Alkynamines for the Synthesis of  Various Heterocyclic Compounds" Under 'DST-Fast Track Projects for Young Scientists' Scheme.
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    "Principal Investigator: Dr. M. Sridhar Reddy (Self)
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    "Synthesis of Marine Natural Products Analogues as Possible Anticancer Agents " Under Ministry of Earth Sciences (MoES), New Delhi.

    •

    "Principal Investigator: Dr. M. Sridhar Reddy (Self)
     
    SELECTED PUBLICATIONS
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    		 Palladium-Catalyzed Regio- and Stereoselective Cross-Addition of Terminal Alkynes to Ynol Ethers and Synthesis of 1,4-Enyn-3-ones. M. H. Babu, V. Dwivedi, R. Kant, M. Sridhar Reddy,* Angew. Chem. Int. Ed. 2015, 54, 3783-3786.
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    		 “Synthesis of 3‑Sulfonylamino Quinolines from 1‑(2-Aminophenyl) Propargyl Alcohols through a Ag(I)-Catalyzed Hydroamination, (2 +3) Cycloaddition, and an Unusual train-Driven Ring Expansion”. Y. K. Kumar, G. R. Kumar, T. J. Reddy, B. Sridhar, M. Sridhar Reddy,* Org. Lett. 2015 ,17, 2226-2229.
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    		 “Iodo Meyer−Schuster Rearrangement of 3-Alkoxy-2-yn-1-ols for β-Mono (Exclusively Z‐Selective)-/Disubstituted α‐Iodo-α,β-Unsaturated Esters”. S. Puri, N. Thirupathi, M. Sridhar Reddy,* Org. Lett. 2014, 16, 5246-5249.
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    		 “Palladium-Catalyzed Tandem Intramolecular Oxy/Amino-Palladation/Isocyanide Insertion: Synthesis of α-Benzofuranyl/Indolylacetamides.”. N. Thirupathi, M. Hari Babu, V. Dwivedi, Ruchir Kant, M. Sridhar Reddy,* Org. Lett. 2014, 16, 2908-2911.
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    		 “Selective 5-exo-dig Cyclization of in Situ Synthesized N-Boc-2-Aminophenyl Ethoxyethynyl Carbenols: Synthesis of Multifunctional Indoles and Their Derivatives.”. N. Thirupathi, Y. Kiran Kumar, Ruchir Kant, M. Sridhar Reddy,* Adv. Synth. Catal. 2014,356, 1823-1834.
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    		 “Cu-Catalyzed Conversion of Propargyl Acetates to E-α,β-Unsaturated Amides via Ketenimine Formation with Sulfonyl Azides.”. Y. Kiran Kumar, G. Ranjit Kumar, M. Sridhar Reddy,* J. Org. Chem. 2014, 79, 823-828.
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    		“Synthesis of Substituted 3-Iodocoumarins and 3-Iodobutenolides via Electrophilic Iodocyclization of Ethoxyalkyne Diols.”. M. Sridhar Reddy,* N. Thirupathi, M. Hari Babu, Surendra Prui. J. Org. Chem. 2013, 78, 5878-5888 (DOI: 10.1021/jo400499r).
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    		 “Tandem aldehyde–alkyne–amine coupling/cycloisomerization: A new synthesis of coumarins.”. M. Sridhar Reddy,* N. Thirupathi, M. Hari Babu, Beilstein J. Org. Chem. 2013, 13, 180-184
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    		 “A New Synthesis of γ-Butyrolactones via AuCl3- or Hg(II)-Catalyzed Intramolecular Hydroalkoxylation of 4-Bromo-3-yn-1-ols”. M. Sridhar Reddy,* Y. Kiran Kumar, N. Thirupathi. Org. Lett. 2012, 14, 824-827.
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    		 “Synthesis of Substituted Coumarins and 2-Quinolinones by Cycloisomerisation of (Hydroxy/aminophenyl)propargyl Alcohols” . Sridhar Reddy,* N. Thirupathi, M. Hari Babu. E. J. Org. Chem. 2012, 5803-5809
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    		 “A Quick and Efficient Access to Substituted Quinolines by Electrophilic Cyclization of 1-(2-aminoaryl)-2-yn-1-ols” M. Sridhar Reddy,* N. Thirupathi, Y. Kiran Kumar. RSC Adv. 2012, 3986-3992.
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    		 “A Highly Efficient Access to Spiroketals, Mono-unsaturated Spiroketals, and Furans: Hg(II)-Catalyzed Cyclization of Alkyne Diols and Triols” K. Ravindar, M. Sridhar Reddy, P. Deslongchamps. Org. Lett., 2011, 13, 3178-3181.
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    		 “Synthesis of the Antiproliferative Agent Hippuristanol and Its Analogues via Suarez Cyclizations and Hg(II)-Catalyzed Spiroketalizations” K. Ravindar, M. Sridhar Reddy, L. Lindqvist,  J. Pelletier, P. Deslongchamps. J. Org. Chem., 2011, 76, 1269-1284.
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    		 “Efficient Synthetic Approach to Potent Antiproliferative Agent Hippuristanol via Hg(II)-Catalyzed Spiroketalization”  K. Ravindar, M. Sridhar Reddy, L. Lindqvist, J. Pelletier, P. Deslongchamps. Org. Lett., 2010, 12 4420-4423
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    		 “Total Synthesis of Ouabagenin and Ouabain” M. Sridhar Reddy, H. Zhang, S. Phoenix, P. Deslongchamps. Chem. Asian J.  2009, 4, 725-741.
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    		 “Total Synthesis of Ouabagenin and Ouabain” H. Zhang, M. Sridhar Reddy, S. Phoenix, P. Deslongchamps. Angew. Chem. Int. Ed., 2008, 47, 1272-1275.
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    		 “Total Synthesis of (+)-Cassaine via Transannular Diels-Alder Reaction” S. Phoenix, M. Sridhar Reddy, P. Deslongchamps. J. Am. Chem. Soc., 2008, 130, 13989-13995.
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    		 “A Highly Stereoselective Total Synthesis of Crocacin C via Prins Cyclisation” J.S.Yadav, M. Sridhar Reddy, P. P.Rao, A.R.Prasad. Synlett 2007, 2049-2052.
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    		 “Stereoselective Syntheses of Basiliskamides A and B via Prins Cyclisation”. J.S.Yadav, P. P.Rao, M. Sridhar Reddy, A.R.Prasad. Tetrahedron Lett., 2008, 49, 5427-5430.
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    		 “Stereoselective Synthesis of (-)-tetrahedronlipstatin via Prins Cyclization”. J.S.Yadav, M. Sridhar Reddy, A.R.Prasad. Tetrahedron Lett., 2006, 47, 4995-4998.
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    		 “Stereoselective Synthesis of anti-1,3-diol Units via Prins Cyclization: Application to the Synthesis of (-)-Sedamine”. J.S.Yadav, M. Sridhar Reddy, P. P.Rao, A.R.Prasad. Tetrahedron Lett., 2006, 47, 4397-4401.
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    		 “Stereoselective Synthesis of Polyketide Precursors Containing an anti-1,3-diol System via Prins Cyclization and Reductive Cleavage Sequence”.  J.S.Yadav, M. Sridhar Reddy, A.R.Prasad. Tetrahedron Lett., 2006, 47, 4937-4941.
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    		 “Enantioselective Synthesis of (+)-Sedamine and (-)-Allosedamine”.  J.S.Yadav, M. Sridhar Reddy, P.P.Rao, A.R.Prasad. Synthesis 2006, 4005-4012.
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    		 “A Convergent Route to ß-hydroxy δ-lactones Through Prins Cyclization as the key step: Synthesis of (+)-Prelactones B, C and V”. J.S.Yadav, M. Sridhar Reddy, A.R.Prasad. Tetrahedron Lett., 2005, 46, 2133-2136.