DR. PINTU KUMAR MANDAL
 
..

Senior Scientist
Medicinal and Process Chemistry Division
Central Drug Research Institute
Lucknow-226031, India
 
Educational Qualifications

M.Sc., Ph.D.
Date of Birth 14.06.1981
Phone 0522-2772450-Ext 4657 (Off.) & 4658 (Lab), Mobile: 91-8005178085
E-Mail

[email protected] , [email protected]
 
EDUCATION AND AWARDS
•
 Post-Doctoral Research:
• Prof.  Peng George Wang’ Laboratory, Department of Chemistry, Georgia State University, Georgia, Atlanta, USA.  Sep 2011- Dec 2012.
• Prof. W. Bruce Turnbull’ Laboratory, Department of Chemistry, University of Leeds, Leeds, UK.  Sep 2009-Aug 2011.
•
 Doctor of Philosophy (Chemistry):
• Jadavpur University (2009)
•
 Awards:
•Newton International Fellow (Royal Society of Chemistry)  (2009-2011) in UK
 
CURRENT RESEARCH AREAS OF INTEREST:
•
 Synthetic  carbohydrate  chemistry,  glycoconjugates  and  use  biophysical  techniques  to  study carbohydrate-proteins interaction.
•

Developing  novel  methods  for  the  stereoselective  synthesis  of  oligosaccharides  and investigating the mechanisms of neighbouring group participation in carbohydrate chemistry.
•
 Design and synthesis of medicinally active heterocycle scaffolds and pharamacophores.
•
 Natural products and natural product mimics.
 
CURRENT PROJECTS:
•
 "Identification of drug targets in Helicobacter pylori using dual-tagged carbohydrates"  'DST-Fast  Track Projects for Young Scientists' Scheme. Principal Investigator: Dr. Pintu Kumar Mandal (Self)
 
SELECTED PUBLICATIONS :
•
 Convergent synthesis of the pentasaccharide repeating unit of the O-antigen of Escherichia coli O36. Pintu Kumar Mandal,* SYNTHESIS 2014, Article in press.
•
 Copper-Catalyzed One-Pot Synthesis of Glycosylated Iminocoumarins and 3-Triazolyl-2-Iminocoumarins. Pintu Kumar Mandal,* RSc Advances, 2014, 4, 5803-5814.
•
 Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4. Pintu Kumar Mandal,* Beilstein J. Org. Chem. 2014, 10, 2724–2728.
•
 Convergent synthesis of a tetrasaccharide repeating unit of the O-specific polysaccharide from the cell wall lipopolysaccharide of Azospirillumbrasilense strain Sp7. Pintu Kumar Mandal,* Debasis Dhara, Anup Kumar Misra. Beilstein J. Org. Chem. 2014, 10, 293-299.
•
 Concise synthesis of the repeating units of the cell wall lipopolysaccharide of Azospirillum brasilense SR80. Pintu Kumar Mandal,* Debasis Dhara, Anup Kumar Misra. SYNTHESIS 2014, 46, 1947–1953.
•
 “Towards a Structural Basis for the Relationship Between Blood Group and the Severity of El Tor Cholera” Pintu K. Mandal,  Thomas  R.  Branson,  Edward  D.  Hayes,  James  F.  Ross,  Jose  A.  Gavín,  Antonio  H. Daranas and W. Bruce Turnbull. Angew. Chem. Intl Ed. (2012), 51,5143-5146.
•
 “Studies on the mechanism of a sulfoxide transfer reaction mediated by diphenyl sulfoxide-triflic anhydride: Martin A. Fascione,Sophie J. Adshead, Pintu K. Mandal,Colin A. Kilner, Andrew G.Leach and W. Bruce  Turnbull: Chemistry - A European Journal; (2012), 18, 2987-2997
•
 “Studies on the synthesis of Lewis-y oligosaccharides: Pintu K. Mandal and W. Bruce Turnbull, Carbohydrate Research (2011), 346, 2113-2120.
•
 “Concise synthesis of the pentasaccharide O-antigen corresponding to the Shiga toxin producing Escherichia coli O171. Pintu Kumar Mandal and Anup Kumar Misra, Bioorganic Chemistry (2010), 38,  56-61.
•
 “Substituted hydrazinecarbothioamide as potent antitubercular agents:Synthesis and quantitative structure- activity relationship (QSAR). Supriya Singh, Pintu K. Mandal, Nagendra Singh, Anup K. Misra , Shubhra  Singh, Vinita Chaturvedi, Sudhir Sinha, Anil K. Saxena, Bioorganic & Medicinal Chemistry Letters (2010) , 20. 2597-2600
•
 “Efficient synthesis of two sialylated tetrasaccharides found in goat milk. Pintu Kumar Mandal and Anup Kumar Misra, Synthesis (2009), 1348-1354.
•
 “Concise synthesis of two pentasaccharides corresponding to the α-chain oligosaccharides of N. gonorrhoeae and N. Meningitidi. Pintu Kumar Mandal and Anup Kumar Misra, Tetrahedron (2008), 64,  8685-8691.
•
 “Concise synthesis of the pentasaccharide O-antigen of Escherichia coli O83:K24:H31    present in the Colinfant vaccine. Pintu Kumar Mandal and Anup Kumar Misra, Glycoconjugate J (2008), 25, 713-722
•
 ““Synthesis of oligosaccharides corresponding to the polysaccharides of Lactobacillus and Thermophlilus strains. Pintu Kumar Mandal, Anup Kumar Misra, Synthesis (2007), 2660-66.
•
 “Mild and efficient hydrolysis of thioglycosides to glycosyl hemiacetals using N-iodosaccharin : Pintu Kumar Mandal, Anup Kumar Misra, Synlett (2007), 1207-1210.
•
 “Concise synthesis of two trisaccharide analogs related to the glycon constituent of Phanoside, a novel insulin releasing natural product. Geetanjali Agnihotri, Pintu Kumar Mandal, Anup Kumar Misra, Tetrahedron (2007), 63, 7240-45.