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| DR. SATISH MISHRA |
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Senior Scientist
Parasitology Division
CSIR-Central Drug Research Institute
Lucknow-226031, India |
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05222772550 Ext. 4529 (Off.) & 4528 (Lab) |
| E-Mail | [email protected] |
| Educational Qualifications |
• Ph.D.2007: CSIR-National Botanical Research Institute and University Of Lucknow,Lucknow, Uttar Pradesh
• M.Sc.(Biotechnology); Devi Ahilya Vishwavidyalaya, Indore, Madhya Pradesh
• BSc, 1999, University of Allahabad, Allahabad, India
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| PROFESSIONAL EXPERIENCE |
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2012-2013: Postdoctoral Fellow, Johns Hopkins University
Bloomberg School of Public Health, USA. |
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2008-2011: Postdoctoral Fellow, New York University
School of Medicine, USA |
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2007-2007: Postdoctoral Fellow, Weizmann Institute of
Science, Israel |
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| HONOURS AND FELLOWSHIPS |
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Ramalingaswami Fellowship from Department of Biotechnology, Govt. of India (2013). |
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Qualified National Eligibility Test in Biotechnology conducted by Indian Council of Agricultural Research (ICAR) in 2003. |
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Qualified National Eligibility Test (CSIR-JRF) in life sciences and scholarship awarded by the Council of Scientific & Industrial Research (CSIR) in 2001. |
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Qualified Graduate Aptitude Test in Engineering (GATE) in life sciences in 2001. |
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Qualified Combined Biotechnology Entrance Examination for pursuing M.Sc and scholarship awarded by the Department of Biotechnology (1999-2001). |
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| RESEARCH INTEREST |
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Pre-erythrocytic stages of Plasmodium
parasites: Basic biology, Functional and Drug targeting approaches |
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| SELECTED PUBLICATIONS |
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Zhang M, Mishra S, Sakthivel R, Fontoura BMA, Nussenzweig V. UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages. PLoS Pathogens. 2016; 12(1): e1005370. |
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Lehmann C, Heitmann A, Mishra S, Burda P-C, Singer M, Prado M, Niklaus L, Ménard R,
Frischknecht F, Stanway R, Sinnis P, Heussler V. A Cysteine Protease Inhibitor of
Plasmodium berghei Is Essential for Exo-erythrocytic Development. PLoS Pathogens. 2014; 10(8): e1004336 |
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Mastan BS, Kumari A, Gupta D, Mishra S, Kumar KA. Gene disruption reveals a dispensable role for Plasmepsin VII in the Plasmodium berghei
life cycle. Mol Biochem Parasitol. 2014; 195(1):10-13. |
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Millholland MG, Mishra S, Dupont CD, Love MS, Patel B, Shilling D,
Kazanietz MG, Foskett JK, Hunter CA, Sinnis P, Greenbaum DC. A Host GPCR
Signaling Network is Necessary for Apicomplexan. Parasite-Mediated Cytolysis.
Cell Host and Microbe, 2013; 13, 15-28 |
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Love MS, Millholland MG, Mishra S, Kulkarni S, Freeman KB, Pan W,
Kavash RW, Costanzo MJ, Jo H, Daly TM, Williams DR, Kowalska MA, Bergman LW,
Poncz M, DeGrado WF, Sinnis P, Scott RW, and Greenbaum DC. Platelet Factor 4
Activity against Plasmodium falciparum and its Translation to Nonpeptidic Mimics
as a New Class of Antimalarials. Cell Host and Microbe. 2012; 12, 815-823. |
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Rudra JS*, Mishra S*, Chong AS, Mitchell RA, Nardin EH,
Nussenzweig V, Collier JH. Self-assembled peptide nanofibers raising durable
antibody responses against a malaria epitope. Biomaterials. 2012; 33,
6476-84. *Equal contribution |
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Zhang M*, Mishra S*, Sakthivel R, Rojas M, Ranjan R, Sullivan
WJ Jr, Fontoura BM, Ménard R, Dever TE, Nussenzweig V. PK4, a eukaryotic
initiation factor 2α(eIF2α) kinase, is essential for the development of the
erythrocytic cycle of Plasmodium. Proc Natl Acad Sci U S A. 2012; 109,
3956-61. *Equal contribution |
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Mishra S*, Nussenzweig RS, Nussenzweig V. Antibodies to
Plasmodium circumsporozoite protein (CSP) inhibit sporozoite's cell traversal
activity. J Immunol Methods. 2012; 377, 47-52.*Corresponding author |
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Mishra S*, Rai U, Shiratsuchi T, Li X, Vanloubbeeck
Y, Cohen J, Nussenzweig RS, Winzeler EA,
Tsuji M, Nussenzweig V. Identification of non-CSP antigens bearing CD8 epitopes
in mice immunized with irradiated sporozoites. Vaccine. 2011; 29,
7335-42. *Corresponding author |
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Kubler-Kielb J, Majadly F, Biesova Z, Mocca CP, Guo C, Nussenzweig R,
Nussenzweig V, Mishra S, Wu Y, Miller LH, Keith JM, Liu TY, Robbins JB,
Schneerson R. A bicomponent Plasmodium falciparum investigational vaccine
composed of protein-peptide conjugates. Proc Natl Acad Sci U S A. 2010;107:1172-77 |
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Mishra S, Yadav DK, Tuli R. Ubiquitin fusion enhances
expression of cholera toxin B subunit in plants and plant expressed protein
binds GM1 receptor more efficiently. J. Biotechnology. 2006; 127,
95-108. |
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REVIEW |
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Kumar KA, Mishra S*. Plasmodium pre-erythrocytic stages: Biology,
Whole Parasite Vaccines and Transgenic models. American Journal of
Immunology, 2012, 8 (3), 88-100. .*Corresponding author |
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PATENT |
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Tuli R, Sawant SV, Ashraf S, Singh PK, Yadav DK, Shahnawaz M, Mishra S.
Chimeric G-protein based rabies vaccine. United States Patent No. US 7,
901,691 B2, Mar. 8, 2011 |
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LAB MEMBERS |
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Hadi Choudhary |
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Roshni Gupta
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Sunil Kumar Narwal
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Ankit Ghosh
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Pratik Narain Srivastava
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