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| Dr.
J.K. SAXENA |
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Chief Scientist
Division of Biochemistry
Central Drug Research Institute,
P.O. Box No. 173
Lucknow 226031 |
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| E-Mail |
[email protected]
jkscdri[at]yahoo dot com |
| Educational qualifications |
M.Sc., Ph.D. |
| Phone No. |
0522-2772450 Extn. 4963 |
| Fax No. |
0522-2771941
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| Date of Birth |
10.10.1955 |
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| POST
DOCTORAL RESEARCH |
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National Institute of
Health, Bethesda (USA)
Department of Biochemistry, Mahidol University, Bangkok, Thailand. |
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| RESEARCH
EXPERIENCE |
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Biochemistry of Parasites (25 years) |
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Molecular
Genetics (10 years) |
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Biotechnology
(5 years) |
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| CURRENT
AREAS OF INTEREST |
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Characterization,
Cloning and expression of enzymes/receptor to be utilized
as chemotherapeutic target(s). |
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| SELECTED
RECENT PUBLICATIONS |
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Bhatia G, Puri Anju, Maurya
R, Yadav PP, Khan MM, Saxena AK and Saxena JK
- Antidyslipidemic and antioxidant activities of different
fractions of Pongamia pinnata (Lin) fruits (2008)
- Med Chem Research 17, 281-289 |
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Joshi S, Singh AR, Kumar
A, Misra PC, Siddiqi MI and Saxena JK
- Molecular cloning and characterization of Plasmodium
falciparum transketolase (2008) - Mol Biochem
Parasitol. 160, 32-41 |
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Khan MM, Saxena R, Puri
Anju, Chander R, Khanna AK, Saxena AK and Saxena JK -
Regulation of glycogen metabolism by antidyslipidemic
action of gemfibrozil and cholestyramine in dyslipidemic
diabetic hamster model (2008) - Med Chem Research
17, 245-257 |
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Kumar A, Saxena JK and
Chauhan PMS - Synthesis of 4-amino-5-cyano -2, 6-Disubsituted
pyrimidines as a potential antifilarial DNA topoisomerase
II Inhibitors (2008) - Medicinal Chemistry
4, 577-85 |
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Sashidhara KV, Rosaiah
JN, Bhatia G and Saxena JK. - Novel keto-enamine
Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h]
chromene-8,10-dicarbaldehyde as potential antidyslipidemic
and antioxidant agents (2008) - Eur.
J. Med. Chem. 43, 2592-6. |
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Sethi A, Paswan S, Srivastava
S, Khare NK, Bhatia A, Kumar A, Bhatia G, Khan MM, Khanna
AK and Saxena JK - A new pregnane glycoside from Marsdenia
roylei as potential antioxidant and antidyslipidemicagents
(2008) - J Asian Nat. Prod Res. 10, 1023-8
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Singh AR, Joshi S, Arya
R, Kayastha AM, Srivastava KK, Tripathi LM and Saxena
JK - Molecular cloning and characterization of
Brugia malayi hexokinase (2008) - Parasitol Int.
57, 354-61 |
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Srivastava S, Joshi Shweta,
Singh Alok Ranjan, Yadav, Sarika Saxena AS, Ram VJ, Chandra
S and Saxena JK - Oxygenated chalcones
and bischalcones as a new class of inhibitors of DNA topoisomerase
of malarial parasites (2008) - Med Chem Research
17, 234-244 |
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Verma SK, Bansal I, Vedi
S, Saxena JK, Katoch VM and Bhattacharya
SM - Molecular cloning, purification and characterisation
of myosin of human lymphatic filarial parasite Brugia
malayi. (2008) - Parasitol Research 102,
481-9 |
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Sethi Arun, Maurya Atul,
Tewari Vibha, Srivastava Sanjay, Faridi Shaheen, Bhatia
Gitika, Khan MM, Khanna AK and Saxena JK
- Expeditious and convenient synthesis of pregnanes and
its glycosides as potential anti-dyslipidemic and anti-oxidant
agents. (2007) - Bioorganic & Medicinal Chemistry
15, 4520-4527 |
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Singh SK, Joshi S, Singh
AR, Saxena JK and Pandey DS. - DNA binding
and topoisomerase ii inhibitory activity of water-soluble
ruthenium(ii) and rhodium(iii) complexes. (2007)
- Inorg Chem 46, 10869-10876 |
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