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| Manish
Kumar Chourasia |
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Senior Scientist
Pharmaceutics Division,
CSIR-Central Drug Research Institute,
Lucknow-226031
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| Educational Qualifications |
M. Pharm. (Dr. H. S. Gour University, Sagar)
Ph.D. (Dr. H. S. Gour University, Sagar) |
| Date of Birth |
1st July 1975 |
| E Mail |
[email protected]
[email protected]
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| PROFESSIONAL EXPERIENCE ( Post-Ph.D.) |
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Sr. Scientist, Pharmaceutics Division, CSIR-Central Drug Research Institute, Lucknow (June 2010 to at present) |
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Postdoctoral Research Fellow, Department of Pharmacy, National University of Singapore, Singapore (Aug 2007 to Aug 2009)
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Scientist, Pharmaceutics Division, CSIR-Central Drug Research Institute, Lucknow (June 2005 to June 2010) |
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Research Officer, Sun Pharmaceutical Advanced Research Centre, Vadodara (Jan 2005 to May 2005) |
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| RESEARCH
FOCUS ( Current Area of Interest) |
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- Drug targeting at different levels (organ, tissue and cell) in leishmaniasis and cancer.
- Design and development of particulate as well as vesicular novel drug delivery systems for the safe and effective treatment of diseases like leishmaniasis and cancer.
Major challenges for formulation scientists are to overwhelm the interference of biological barriers that restrict the access of drugs to target sites and also to design and develop delivery systems/drug products with desirable therapeutic value. Our research group is focused on the development of safe and effective novel delivery systems in order to protect and transport bioactive agents for the treatment and management of life threatening diseases such as leishmaniasis and cancer. We are particularly working on the different levels of drug targeting employing particulate (nano/microparticles) and vesicular drug delivery systems. Receptor targeting and ligand based drug delivery approach are the areas, we are interested in. Enhancement of delivery of poorly water soluble drugs is another research field we are exploring through the use of nanoemulsion and polymeric micelles. We are also determined for the development of different pharmaceutical dosage forms (conventional and NDDS), which will be an amalgamation of academics as well industrial significance. |
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| RESEARCH
GROUP |
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Salini Asthana (SRF)
Vivek K Power (SRF)
Pankaj Singh (SRF)
Yuvraj Singh (JRF)
Jaya Gopal Meher (JRF)
Annie Gupta (Project Assistant) |
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| RESEARCH
GRNT RECEIVED |
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Grant-in-aid project entitled “Investigation of effect of polysaccharide in modifying leishmanicidal potential of nanoparticulate system bearing chemotherapeutics agent”
Funded by: Department of Biotechnology, Government of India, INR 21.7 Lakhs (Oct 2011 to Oct 2014) |
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Working as team member in 5 CSIR network projects of 12th five year plan (2012-17) |
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PUBLICATION DETAILS
List of representative publications (last three years) |
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Asthana S., Jaiswal A.K., Gupta P.K., Pawar V.K., Dube A., Chourasia M.K., Immunoadjuvant chemotherapy of visceral leishmaniasis in hamsters using amphotericin B-encapsulated nanoemulsion template-based chitosan nanocapsules, Antimicrob. Agents Chemother, 57(4),1714-22, 2013. |
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Gupta A., Asthana S., Konwar R., Chourasia M.K., An insight into potential of nanoparticles-assisted chemotherapy of cancer using gemcitabine and its fatty acid prodrug: a comparative study, J. Biomed. Nanotechnol., 9, 915-925 (2013) |
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Pawar V.K., Kansal S., Asthana S., Chourasia M.K., Industrial perspective of gastroretentive drug delivery systems: physicochemical, biopharmaceutical, technological and regulatory consideration, Expert. Opin. Drug Deliv., 9(5), 551-65, 2012. |
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Singh P., Gupta A., Jaiswal A., Dube A., Mishra S., Chourasia M.K. Design and development of Amphotericin B bearing polycaprolactone microparticles for macrophage targeting. J. Biomed. Nanotechnol. 7, 50-51, 2011. |
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Chourasia M.K., Kang L. and Chan S.Y., Nanosized ethosomes bearing ketoprofen for improved transdermal delivery, Results Pharm. Sci., 1, 60-67, 2011. |
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Kunjachan S., Gupta S., Dwivedi A.K., Dube A., Chourasia M.K., Chitosan based macrophage mediated drug targeting for the treatment of experimental visceral leishmaniasis, J. Microencap., 28, 301-310, 2011. |
Book Chapters: |
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“Polysaccharides for colon specific drug delivery” in a book entitled “Progresses in controlled and novel drug delivery” (edited by N. K. Jain), 3rd Edition, CBS Publication, New Delhi, India |
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International/ national seminal workshop: |
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Delivered scientific talk/lecture in 12 international/national seminars and workshops |
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Honors/Awards |
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Second best poster award for the session cancer nanotechnology at the NANOBIO 2012: Second international conference on nanotechnology at the biomedical interface, Kochi, 2012 |
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CRS-Capsugel/Pfizer innovative aspects of oral drug delivery and absorption Graduate/Post-Doc award, Honolulu, Hawaii, USA, 2004 |
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M. L. Khurana Memorial Prize for best research paper in Ind. J. Pharm. Sci., 56th Indian Pharmaceutical Congress, Kolkata, India, 2004 |
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IDMA’s best research paper award for publication in Indian Drugs, Mumbai, India, 2004 |
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Best Oral Presentation Award, National Science Day, Dr. Hari Singh Gour, University, Sagar, M.P., India, 2003 |
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Awarded university gold medal for appearing first class first in B. Pharm. Examination, Sagar, M. P., India, 1997 |
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G. P. Nair award by Indian Drug Manufacturers association, Mumbai, India, 1998 |
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M. L. Khurana award for appearing first class first in B. Pharm. Examination, Mumbai, India, 1998 |
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