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| Dr.
P.K. SHUKLA |
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Senior Principal Scientist
In-Charge Microbiology Division
Central Drug
Research Institute,
LUCKNOW 226 031, INDIA
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| POSITIONS
HELD |
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| Lecturer in Medical Mycology
T.U.Teaching Hospital nstitute of Medicine Maharajgunj, Kathmandu,
Nepal |
| Present Position : Senior Principal Scientist,
Microbiology Division, CDRI, Lucknow |
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| RESEARCH
EXPERIENCE/TRAINNING |
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Senior Research Fellow and Research Associate (ICMR, New
Delhi, India) |
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Department
of Ophthalmology, King George's Medical College, and Medical
Mycology Division,
C.D.R.I., Lucknow, India. |
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| CURRENT
AREAS OF INTEREST |
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Medical Mycology,
Immunodiagnosis |
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Chemo/Immuno
therapy of fungal infection |
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| MEMBERSHIPS
OF PROFESSIONAL SOCIETIES |
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International
Society for Human and Animal Mycology (USA) |
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Society for
Indian Human and Animal Mycologists (SIHAM), India, Life
member |
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International
Society of Applied Biology, India, Life member |
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The U.P.Association
for the Science and Technology Advancement. Life member |
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| Honours
and Awards : Received best paper presentation
award at the 32nd Annual Conference of Association of
Microbiologists of India, Madurai (Jan10-12, 1992) |
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| Publications
and Patents: More than 110 papers and 14 patents.
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| Selected
Publications |
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Kiran Kumar STVS, Kumar
Lalit, Sharma,Vishnu L. Jain Ashish, Jain, Rajeev K, Maikhuri
Jagdamba P, Kumar Manish, Shukla Praveen K
and Gupta Gopal. Carbodithioic acid esters of fluoxetine,
a novel class of dual-function spermicides. (2008)
Eur. J. Med. Chem. 43, 2247-2256 |
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Saxena N, Singh N, Mishra
M, Keshava GB, Shukla PK and Tripathi
RP. Synthesis of azatricyclodiones & octahydro-benzo[f]isoindoles
and their antimicrobial evaluation. (2008) Journal
of Enzyme Inhibition and Medicinal Chemistry
23, 476-482 |
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Shukla PK,
Kumar M and Keshava GBS. Mycotic keratitis: an overview
of diagnosis and therapy. (2008) Mycoses
51, 183-199 |
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Singh DN, Verma N, Raghuwanshi
S, Shukla PK and Kulshreshtha DK. Antifungal
activity of Agapanthus africanus extractives. (2008)
Fitoterapia 79, 298-300 |
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Candidacidal activity
of a monoclonal antibody that binds with glycosyl moieties
of proteins of Candida albicans Wall Proteins. Amol Kavishwar
and P.K Shukla. Medical Mycology
(2006), 44, 159-167. |
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Use of PCR targeting of
internal transcribed spacer regions and single-stranded
conformation polymorphism analysis of sequence variation
in different regions of rRNA genes in fungi for rapid
diagnosis of mycotic keratitis. Manish Kumar and
P.K.Shukla (2005). J.
Clin. Microbiol.vol. 43 (2), 662-668. |
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Synthesis of 4-hydroxy-1-methylindole
and benzo[b]thiophen-4-ol based unnatural flavonoids as
new class of antimicrobial agents. Prem P. Yadav, Prasoon
Gupta, A.K.Chaturvedi, P.K.Shukla and
Rakesh Maurya. (2005). Bioorg. Med. Chem.
13, 1497-1505. |
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Identification of a novel
antifungal nonapeptide generated by combinatorial approach.
Manish kumar, Ashok k. Chaturvedi, Amol Kavishwar, P.K.Shukla,
A.P. Kesarwani and B. Kundu. (2005) International
J. Antimicrob. Agents. 25, 313-320. |
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Synthesis of (1,4)-naphthoquinono-(3,2-c)-1
H-pyrazoles and their (1,4)-naphthohydroquinone derivatives
as antifungal antibacterial and anticancer agents. V.K.Tandon,
D.B.Yadav, A.K.Chaturvedi and P.K.Shukla. (2005).
Bioor. Med. Chem. Lett. 15, 3288-3291. |
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Synthesis and biological
evaluation of novel1,4-naphthoquinone derivatives as antibacterial
and antiviral agents. V.K. Tandon, D.B. Yadav, R.V. Singh,
Meenu Vaish, A.K. Chaturvedi and P.K. Shukla.
Bioor. Med. Chem. Lett. 2005. 15, 3463-3466. |
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Discovery of substituted
isoxazolecarbeldehydes as potent spermicides, acrosin
inhibitors and mild antifungal agents.G. Gupta, R.K.Jain,
J.P.Maikhuri, P.K.Shukla, M. Kumar, K.Roy,
A. Patra, V. Singh and S. Batra. Human Reproduction
2005. 20, 2301-2308. |
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Identification of Aspergillus
fumigatus secretory proteins and their immunohistochemical
demonstration in mouse model. S.K Raghuwanshi, Manish
Kumar, A. Kavishwar, Ashok K. Chaturvedi, P.S.R Murthy
and P.K. Shukla. Mycoses (2005).
48, 313-320. |
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Monoclonal Immunoglobulin
G1 directed against Aspergillus fumigatus cell wall glycoprotein
protects against experimental murine aspergillosis. A.K.Chaturvedi,
A. Kavishwar, G.B.Shiva Keshava and P.K.Shukla.
Clinical and Diagnostic Laboratory Immunology (2005)
12, 1063-1068. |
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Sensitive and rapid PCR
based diagnosis of mycotic keratitis through single stranded
conformation polymorphism Manish Kumar, N.K.Mishra, and
P.K.Shukla. American J. Ophthalmology
(2005) 140 (5), 858-865. |
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Synthesis and biological
evaluation of novel (L)-a-amino acid methyl ester, heteroalkyl,
and aryl substituted 1,4-naphthoquinone derivatives as
antifungal and antibacterial agents. Vishnu K. Tandon,
Dharmendra Yadav, Ravindra V. Singh, Ashok K. Chaturvedi
and P.K. Shukla. Bioorganic &
Medicinal Chemistry Letters 15 (2005) 5324-5328.
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