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Dr. Prem Prakash Yadav |
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Sr. Scientist
Medicinal and Process Chemistry Division
Central Drug Research Institute
Lucknow 226031, UP, India
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| Educational Qualifications |
M.Sc., Ph.D. |
| Phone No. |
+91-0522-2772450 Ext: 4761 |
| Fax No. |
+91-0522-2771941 |
| E- mail |
[email protected]
, [email protected] |
| Date of Birth |
06.03.1978 |
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| EDUCATION AND AWARDS |
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2016 CSIR-CDRI Incentive award for publications 2016 |
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Post-Doctoral Research: Prof. HartmutLaatsch, Institute of Organic and Biomolecular Chemistry, Goettingen University, Germany, Oct-2008 to Sept-2009. |
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Doctor of Philosophy (Chemistry) : Doctoral Research was carried out at Central Drug Research Institute, Lucknow, India, 2001- 2005. Degree awarded from Avadh University, Faizabad |
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Awarded Senior Research Fellowship (SRF-CSIR, New Delhi)-2005 |
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Qualified GATE-2001 |
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Master of Science (Organic Chemistry): Organic Chemistry; Allahabad University, UP, India, 1999-2001 |
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| RESEARCH GROUP |
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Mr. AnandDevireddy (SRF, CSIR) |
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Miss Parul Chauhan (SRF, CSIR) |
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Mr. Om P. S. Patel (SRF, UGC) |
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Mr. Rahul Kumar Maurya(SRF, CSIR) |
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Miss Shikha Singh (SRF, CSIR) |
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Miss Deepika Saini (PA, CSIR) |
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Mr. Ajay Mahor(Trainee, NIPER) |
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Mr. Anoop Kumar Srivastava, Sr.Technician-(2) |
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Ph.D Awarded |
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Dr.Makhtala Ravi (2015) |
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| CURRENT AREAS OF INTEREST |
| Identification of novel/bioactive natural products from plants and microbial sources. |
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| Synthesis of bioactive molecules/Development of synthetic methodologies for late stage functionalization of bioactive compounds. |
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| J. Org. Chem.2015, 80, 12410−12419. |
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| Green Chem.2015, 17, 3728-3732. |
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| J. Org. Chem.2015, 80, 5369−5376. |
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| ACS Med. Chem. Lett.,2013, 4,165–169. |
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| Synlett2013, 24, 173–176. |
| SELECTED
PUBLICATIONS |
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P. Chauhan, M. Ravi, S. Singh, P. Prajapatiand Prem. P. Yadav*: Regioselective a-arylation of coumarins and 2-pyridones with phenylhydrazines under transitionmetal-free conditions;RSC Adv.,2016, 6, 109-118.
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DevireddyAnand, Om P. S. Patel, Rahul K. Maurya and Prem P. Yadav*: Substrate Controlled Synthesis of Benzisoxazole and Benzisothiazole Derivatives via PhI(OAc)2‑Mediated Oxidation Followed by Intramolecular Oxidative O−N/S−N Bond Formation; J. Org. Chem.2015, 80, 12410−12419. |
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S. Singh, P. Chauhan, M. Ravi, I. Taneja, Wahajuddin and Prem. P. Yadav*: A mild CuBr–NMO oxidative system for the coupling of anilines leading to aromatic azo compounds: RSC Adv.,2015, 5, 61876-61880. |
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Om P. S. Patel, DevireddyAnand, Rahul K. Maurya and Prem P. Yadav*: Copper-catalyzed highly efficient oxidative amidation of aldehydes with 2-aminopyridines in an aqueous micellar system: Green Chem.2015, 17, 3728-3732. |
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M. Ravi, P. Chauhan, R. Kant,Sanjeev K. Shuklaand Prem. P. Yadav*: Transition-Metal-Free C-3 Arylation of Quinoline-4-ones with Arylhydrazines: J. Org. Chem.2015, 80, 5369−5376. |
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P. Chauhan, M. Ravi, S. Singh, K. S. R. Raju, V. Bajpai, B. Kumar, Wahajuddin and Prem. P. Yadav*: Palladium and copper-catalyzed ligand-free coupling of phenylhydrazines in water: RSC Adv.,2014, 4, 43336-43340. |
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Muheeb Beg, Parul Chauhan, SalilVarshney, Kripa Shankar, SujithRajan, Deepika Saini, MN Srivastava, Prem P Yadav,* Anil Nilkanth Gaikwad*. “A withanolidecoagulin-L inhibits adipogenesis modulating Wnt/β-catenin pathway and cell cycle in mitotic clonal expansion”. Phytomedicine2014, 21(4), 406-414. |
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RanjaniMaurya, AwakashSoni,DevireddyAnand, Makthala Ravi, Kanumuri S. R. Raju, IshaTaneja,Niraj K. Naikade, S. K. Puri,Wahajuddin, Sanjeev Kanojiya,PP Yadav*, “Synthesis and Antimalarial activity of 3,3-spiroanellated 5,6-disubstituted-1,2,4-trioxanes”. ACS Med. Chem. Lett.2013, 4(2), 165-169. |
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Makthala Ravi, DevireddyAnand, RanjaniMaurya, Parul Chauhan, Niraj K. Naikade, Sanjeev K. Shukla, Prem P. Yadav*, “Synthesis of 1,2,4-Trioxepanes and 1,2,4-Trioxanes via H2O2-Mediated Reaction of Tertiary Carbinols”. Synlett2013, 24, 173. |
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Bandana Chakravarti, RanjaniMaurya, Jawed Akhtar Siddiqui, Hemant Kumar Bid, S. M. Rajendranc, Prem P. Yadav*, RiturajKonwar*. “In vitro anti-breast cancer activity of ethanolic extract of Wrightiatomentosa: Role of proapoptotic effects of oleanolic acid and urosolic acid”.Journal of Ethnopharmacology2012, 142,72-79. |
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Ranjani Maurya , Anuj Srivastava , Priyanka Shah, Mohammad Imran Siddiqi, S. M. Rajendran,Anju Puri, Prem P. Yadav*. “β-Amyrin acetate and β-Amyrin palmitate as antidyslipidemic agents from Wrightia tomentosa leaves”.Phytomedicine2012, 19, 682-685. |
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Muna Ali Abdalla, Prem P. Yadav, Birger Dittrich, AnjaSchueffler, HartmutLaatsch.“ent-Homoabyssomicins A and B, Two New Spirotetronate Metabolites from Streptomyces sp. Ank 210”. Organic Letters 2011, 13(9), 2156-2159. |
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Prem P. Yadav, Vimal Nair, Birger Dittrich, AnjaSchueffler, HartmutLaatsch. “Lucknowlides A and B, tricyclic ketal-lactone metabolites from terrestrial Streptomyces Sp.” Organic Letters 2010, 12(17), 3800-3803. |
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Prem P. Yadav, RanjaniMaurya, Jayanta Sarkar, Ashish Arora, Sanjeev Kanojiya, Sudhir Sinha, M.N. Srivastava, Ram Raghubir. “CassaneDiterpenes from Caesalpiniabonduc”Phytochemistry 2009, 70, 256–261. |
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Sanjeev Kanojiya and Prem P. Yadav. “Fragmentation patterns of newly isolated cassanebutenolidediterpenes and differentiation of stereoisomer by tandem mass spectrometry” J. Mass Spectrometry 2008, 43, 1413-1420 |
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Prem P. Yadav, Ashish Arora, Hemant K. Bid, Ritu R. Konver, Sanjeev Kanojia.“New cassanebutenolidehemiketalditerpenes from the marine creeper Caesalpiniabonduc and their antiproliferative activity” Tetrahedron Letters 2007, 48, 7194-7198 |
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Prem P. Yadav, Prasoon Gupta, A. K. Chaturvedi, P. K. Shukla, Rakesh Maurya. “Synthesis of 4-hydroxy-1-methylindole and benzo[b]thiophen-4-ol based unnatural flavonoids as new class of antimicrobial agents” Bioorganic and Medicinal Chemistry 2005, 13, 1497-1505. |
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Prem P. Yadav, Ghufran Ahmad and Rakesh Maurya. An efficient route for commercially viable syntheses of furan- and thiophene-anellated ß- hydroxychalcones.Tetrahedron Letters 2005, 46, 5621-5624. |
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R. Maurya, Prem P. Yadav. Furanoflavonoids: An Overview. Natural Product Reports2005, 22(3), 400 - 424. |
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G. Ahmad, Prem P. Yadav, R. Maurya. Furanoflavonoid glycosides from Pongamiapinnata fruits. Phytochemistry2004, 65, 921-924. |
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Prem P. Yadav, G. Ahmad, R. Maurya. Furanoflavonoids from Pongamiapinnata fruits. Phytochemistry 2004, 65, 439-443. |
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