Dr. Sudheer K Singh
 
 



Sr. Scientist
Division of Microbiology,
CSIR-CDRI, Lucknow India
 
E-Mail

[email protected] , [email protected]
Phone 091-522-2772450, ext-4429
Educational qualifications MSc Biotechnology (BHU), MTech Biochemical Engineering (BHU), PhD (VBSPU)
Date of birth

28.12.1970
 
EXPERTISE
•
 Mycobacterium biology, Bioprocess development
 
CURRENT AREAS OF INTEREST
The activities of our lab can be broadly classified as basic and applied aspects of TB research:
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 The basic aspect of our activities pertains to understanding the role of metabolic pathways involved in carbon, nitrogen, energy and co-factor metabolism of Mycobacterium tuberculosis (Mtb) and their role in mycobacterial survival and persistence. To elucidate the role of selected pathways we develop recombinant Mtb strains and study them under in vitro and, ex vivo in vivo growth conditions.
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 The applied aspect of our activities include: a) Developing target specific screening systems for identification of inhibitors of Mycobacterium tuberculosis. These systems offer significant advantages over in vitro inhibition assays using purified proteins as identified inhibitors are not affected by permeability and efflux issues. b) Screening of inhibitors against Mtb malate synthase (GlcB).
 
SELECTED PUBLICATIONS
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 Kumar Sachin Singh, SK Singh. (2015). Scientific Reports | 5:16131 | DOI: 10.1038/srep16131
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 A Bhardwaj, S Mehta, S Yadav, SK Singh, A Grobler, AK Goyal, & A Mehta. (2015). Artificial Cells, Nanomedicine, and Biotechnology, DOI: 10.3109/21691401.2015.1062389
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 A Raj, S Kumar, I Haq and SK Singh. (2014). Eco. Eng. 71, 355-362
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 Ashok K Singh, Ravindra K Singh, M Arshad, Sahabjada, SK Singh, & Ragini Sinha. (2014). Indian J Chemistry. 53B (6), 769-774.
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 A Raj, S Kumar, SK Singh and M Kumar. (2013). Scientific.World J. DOI:10.1155/2013/386769.
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 J Vidya, S Swaroop, SK Singh, D Alex, RK Sukumaran and A Pandey. (2011). Biologia, 66: 939—944.
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 NS Shaligram, SK Singh, RS Singhal, A Pandey, G Szakacs.  (2009). Appl Biochem Biotech, 159: 505-520.
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 NS Shaligram, M Bule, R Bhambure, RS Singhal, SK Singh, G Szakacs, and A Pandey (2009). Process Biochemistry, 44: 939-943.
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 NS Shaligram, SK Singh, RS Singhal, G Szakacs, A Pandey. (2009). J. Microbiol. Biotechnol, 19: 690–697.
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 SU Ahmed, KK Reddy, SL Swathy, SK Singh, S Kanjilal, RBN Prasad and A Pandey (2009). Food Research International, 42: 449–453.
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 SU Ahmed, SK Singh, A Pandey, S Kanjilal and RBN Prasad. (2009). Appl Biochem Biotechnol, 152: 108-116.
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 SU Ahmed, SK Singh, A Pandey, S Kanjilal and RBN Prasad. (2008). Appl Biochem Biotechnol, 151: 599-609.
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 NS Shaligram, SK Singh, RS Singhal, G Szakacs, A Pandey. (2008). Biochemical Eng J., 41: 295–300.
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 SK Singh, S Chakraborty, AK Singh and PK Pandey. (2006). Bioresource Technology 97: 1807-1814.
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 SU Ahmed, SK Singh, A Pandey, S Kanjilal and RBN Prasad. (2006). Food Technology and Biotechnology, 44 (2): 283-287.
 
PATENTS
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 PS Saudagar, SK Singh, RS Singhal & A Pandey, Derwent Primary Accession Number: 2008-N23244 [77]; Patent Number(s): WO2008132531-A1
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 SU Ahmed, SK Singh and Ashok Pandey, 0009NF2008; 0182DEL2009/IN.
 
Book Chapters
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 SK Singh, G Szakacs, CR Soccol, and   A Pandey. (2008). In: Current developments in solid state fermentation, (Eds) A Pandey,  CR Soccol, C Larroche, XI: 181-204, Springer, ISBN: 978-0-387-75212-9.
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 SK Singh. (2007), In: Applications of Biotechnology, (Eds.) BN Tripathi, GS Shekhavat, and V Sharma, 3: 30-42, Avishkar Publications, New Delhi
 
Review Articles  
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 SK Singh & A Pandey. (2013). Appl Biochem Biotechnol. 171:927-938. DOI 10.1007/s12010-013-0400-2.
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 S Ramchandran, SK Singh, C Larroche, CR Soccol. A. Pandey. (2007). Bioresource Technology, 98: 2000–2009.
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 SK. Singh, SU Ahmed & A Pandey. (2006). Process Biochemistry, 41: 991-1000.
 
PhD Students
•
 Mr. Kumar Sachin Singh (SRF)
•
 Mr. Rishabh Sharma (SRF)
•
 Ms. Deepa Keshari (SRF)
Project Student
•
 Shailendra Yadav
Gene Bank Submissions: 21