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VINEETA CHATURVEDI |
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Senior
Principal Scientist
Biochemistry Division
Central Drug Research Institute
LUCKNOW- 226031
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| Educational qualifications |
M. Sc.(Agra College Agra), Ph. D.(S N Medical College, Agra) |
| Date of Birth |
10.07.1963
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| E mail |
[email protected] |
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POST-DOCTORAL RESEARCH |
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Dec., 1988- Dec.,1991
Division of Immunology, Central JALMA Institute of leprosy and Other Mycobacterial Diseases, Agra
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AREA OF SPECIALIZATION |
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- Microbiology and immunology of mycobacterial infections
- TB Drug Discovery
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| ACADEMIC AWARDS/ HONOURS |
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IMMUNOLOGY
FOUNDATION AWARD of Indian Association of Leprologists. 2007 |
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ACWORTH LEPROSY
HOSPITALRESEARCH SOCIETY AWARD of Indian Association
of Leprologists.1992 |
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HIGH QUAILTY RESEARCH WORK Award of Hamdard
National Foundation .1987 |
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YOUNG
SCIENTIST Award of Indian Science Congress. 1989 |
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| LAB MEMBERS |
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Junior Technical Assistant(Gr. III)
Ms. Priyanka Trivedi
Senior Technician (Gr.II)
Mr. Hori Lal
Ph.D. Students
Ms. Shubhra Singh (SRF)
Ms. Richa Dwivedi (SRF) |
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| PUBLICATIONS |
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- Total 54 original research articles in SCI journals.
Citations to all publicatios: sum of times sited-571. |
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| PATENTS (23) |
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| SELECTED
PUBLICATIONS |
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Chauhan K, Sharma M, Saxena J, Singh VS, Trivedi P, Srivastava K, Puri SK, Saxena JK, Chaturvedi V, Chauhan PMS. 2013. Synthesis and biological evaluation of a new class of 4-Amino quinoline- rhodanine hybrid as potent anti infective agents. Eur J Medicinal Chem. 62: 693-704. |
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Singh S, Dwivedi R and Chaturvedi V. 2012. Influence of vehicles used for oral
dosing of test molecules on the progression of Mycobacterium tuberculosis infection in mice. Antimicrobial Agents Chemotherapy 56(11): 6026-6028. |
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Vijay K. Marrapu , Vinita Chaturvedi, Shubhra Singh , Shyam Singh , S Sinha,
Kalpana Bhandari. 2011. Novel aryloxy azolyl chalcones with potent activity against Mycobacterium tuberculosis H37Rv. European Journal of Medicinal Chemistry . 46, 4302-4310. |
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Bisht, S. S., N. Dwivedi, V Chaturvedi, N. Anand, M.Misra, R. Sharma, B. Kumar, R.Dwivedi, S. Singh, S. K. Sinha,V. Gupta, P. R. Mishra, A. K. Dwivedi, and R. P. Tripathi.2010.Synthesis and Optimization of Antitubercular Activities in a Series of 4-(Aryloxy) Phenyl Cyclopropyl Methanols'. European Journal of Medicinal Chemistry 45(12), 5965-5978. [CI= 0, IF 3.193] |
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Sunduru Naresh, Gupta Leena, Chaturvedi Vinita, Dwivedi, Richa, Sinha Sudhir and Chauhan PMS. 2010. Discovery of New 1,3,5-TriazineScaffolds with Potent Activity against Mycobacterium tuberculosis. European Journal of Medicinal Chemistry 45(8), 3335-3345. |
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Pandey J, Tiwari VK, Verma SS, Chaturvedi V, Bhatnagar S, Sinha S, Gaikwad AN and Tripathi RP. 2009. Synthesis and antitubercular screening of imidazole derivatives. Eur. J. Med. Chem 44(8), 3350-3355. |
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Sharma M, Chaturvedi V, Manju YK, Bhatnagar S, Srivastava K, Puri SK and
Chauhan PMS. 2009. Substituted quinolinyl chalcones and quinolinyl pyrimidines as a new class of anti- infective agents. Eur. J. Med. Chem 44(5), 2081-2091. |
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Singh N, Pandey J, Yadav A, Chaturvedi V, Bhatnagar S, Gaikwad AN, Sinha SK, Kumar A, Shukla PK and Tripathi RP. 2009. A facile synthesis of alpha,alpha'-(EE)- bis(benzylidene)-cycloalkanones and their antitubercular evaluations. Eur. J. Med. Chem 44(4), 1705-9. (CI=14, IF= |
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Tripathi RP, Yadav AK, Bisht SS, Chaturvedi V and Sinha SK. 2010 . Application of Huisgen (3+2)cycloaddition reaction: Synthesis of 1-(2,3- dihydrobnzofuran-2-yl methyl [1,2,3]-triazoles and their Antitubercular evaluations. Eur. J. Med. Chem 45, 142-148. |
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Pandey J, Tiwari VK, Verma SS, Chaturvedi V, Bhatnagar S, Sinha S, Gaikwad AN, Tripathi RP. 2009. Synthesis and antitubercular screening of imidazole derivatives. European J Medicinal Chem 44: 3350-3355. |
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Tripathi RP, Yadav AK, Bisht SS, Chaturvedi V and Sinha SK. 2009. Application of Huisgen (3+2)cycloaddition reaction: Synthesis of 1-(2,3-dihydrobnzofuran-2-yl methyl [1,2,3]-triazoles and their Antitubercular evaluations. Eur. J. Med. Chem. 44, 335-355. |
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Singh N, Pandey J, Yadav A, Chaturvedi V, Bhatnagar S, Gaikwad AN, Sinha SK, Kumar A, Shukla PK and Tripathi RP. 2009. A facile synthesis of alpha,alpha'-(EE)-bis(benzylidene)-cycloalkanones and their antitubercular evaluations. Eur. J. Med. Chem. 44(4), 1705-9. |
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Sharma M, Chaturvedi V, Manju YK, Bhatnagar S, Srivastava K, Puri SK and Chauhan PMS. 2009. Substituted quinolinyl chalcones and quinolinyl pyrimidines as a new class of anti-infective agents. Eur. J. Med. Chem. 44(5), 2081-2091. |
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Pandey J, Tiwari VK, Verma SS, Chaturvedi V, Bhatnagar S, Sinha S, Gaikwad AN and Tripathi RP. 2009. Synthesis and antitubercular screening of imidazole derivatives. Eur. J. Med. Chem. 44(8), 3350-3355. |
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Pandey Jyoti, Sharma Anindra, Tiwari VK, Dube Divya, Ramachandran
Ravishankar, Chaturvedi Vinita, Sinha SK, Mishra NN, Shukla PK and Tripathi RP.2009. Solution-Phase Synthesis of a Library of Carbapeptide Analogues Based on Glycosylamino Acid Scaffolds and Their In Silico Screening and Antimicrobial Evaluation. Journal of Combinatorial Chemistry, 11(3), 422-427. |
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Pandey J, Tiwari VK, Verma SS, Chaturvedi V, Bhatnagar S, Sinha S, Gaikwad AN, Tripathi RP. Synthesis and antitubercular screening of imidazole derivatives. 2009. European J Medicinal Chem 44: 3350-5. |
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Kumar A, Chaturvedi V, Bhatnagar S, Sinha S, Siddiqui MI. 2009. Knowledge based identification of potent antitubercular compounds using structure based virtual screening and interaction of fingerprins. J Chemical Information and Modelling 49: 35-42. |
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G Panda, MK Parai, SK Das, Shagufta, M Sinha, Vinita Chaturvedi, AK Srivastava,
YK Manju, AN Gaikwad, S Sinha, 2007. Effect of substituents on diarylmethanes for
antitubercular activity. European Journal of Medicinal Chemistry 42, 410-419. |
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M Saquib, MK Gupta, R Sagar, YS Prabhakar, AK Shaw, R Kumar, PR Maulik, A Gaikwad, S Sinha, AK Srivastava, Vinita Chaturvedi, R Srivastava, BS Srivastava. 2007. C-3 alkyl/arylalkyl1-2,3-dideoxy hex-2-enopyranosides as antitubercular agents: synthesis, biological evaluation and QSAR study. Journal of Medicinal Chemistry 50, 2942-50. |
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Vinita Chaturvedi, B K. Girdhar, U Sengupta and S Sinha, 2007. Semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings: Suitability as a laboratory aid for field diagnosis of leprosy. Transactions of Royal Society of Tropical Medicine and Hygiene 101, 699-706. |
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Vinita Chaturvedi, N Dwivedi, RP Tripathi and S Sinha, 2007. Identification and evaluation of Mycobacterium smegmatis as a possible surrogate screen for selecting molecules active against multi-drug resistant Mycobacterium tuberculosis. Journal of General and Applied Microbiology 53, 333-337. |
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D Katiyar, VK Tiwari, N Tewari, SS Verma, S Sinha, A Gaikwad, A Srivastava, Vinita Chaturvedi, R Srivastava, BS Srivastava, RP Tripathi, 2005. Synthesis and antimycobacterial activities of glycosylated amino alcohols and amines. European Journal of Medicinal Chemistry 40, 351-360. |
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Chaturvedi V and Gupta HP. 2001. Evaluation of integral membrane antigens of
Mycobacterium habana for serodiagnosis of extrapulmonary tuberculosis : Association between levels of antibodies and Mycobacterium Tuberculosis antigens. FEMS Immunol MED Microbiol 33, 1-7. |
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Chaturvedi V, Srivastava A, Gupta HP and Srivastava BS.1999. Protective proteins of Mycobacterium habana are distributed between peripheral and integral compartments of plasma membrane. A study in experimental tuberculosis of mouse. Vaccine 17: 2882-2887 |
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Chaturvedi V, Sinha S,Girdhar B K,Katoch K, Bhatia A S and Sengupta U.1991. Association of mycobacterium –specific and M.leprae specific antibody levels with clinical activity in tuberculoidleprosy: Acomparative study of three serological enzyme assays. Lepr Rev 62: 122-133. |
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Chaturved V, Sinha S, Girdhar B K and Sengupta U. 1991. On the value of sequentialserology with Mycobacterium leprae specific antibody competition ELISA in monitoring leprosy chemotherapy. |
Patents |
Foreign Patents |
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. Patent Number: US2007248704-A1
Title: Method, useful for treating tuberculosis, comprises administering an antitubercular extract or fraction obtained from a Salicrnia species.
Inventors: RATHOD M R; SHETHIA B D; PANDYA J B; GHOSH P K; DODIA P J; SRIVASTAVA B S; SRIVASTAVA R; SRIVASTAVA A; CHATURVEDI V. |
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Patent Number: US2005186291-A
Title: New bioactive fraction from extracts of salicornia species useful as anti tubercular agent for the treatment of tuberculosis.
Inventors: RATHOD M R; SHETHIA B D; PANDYA J B; GHOSH P K; DODIA P J; SRIVASTAVA B S; SRIVASTAVA R; SRIVASTAVA A; CHATURVEDI V. |
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. Patent Number: WO2005115424-A1; IN200400969-I1; US2007020351-A1; AU2005247206-A1; MX2006011593-A1; BR200510918-A; JP2008501041-W
Title: Bioactive fraction useful as antitubercular agent for treatment of tuberculosis, comprises extracts of Salicornia species e.g. Salicornia brachiata
Inventors: RATHOD M R; SHETHIA B D; PANDYA J B; GHOSH P K; DODIA P J; SRIVASTAVA B S; SRIVASTAVA R; SRIVASTAVA A; CHATURVEDI V; VIRAMANI M; RATHOD R M; BHUPENDRA D; MARIAPPANADAR V; VAIRAMANI M |
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Patent Number: WO2005021020-A1; AU2003259548-A1; EP1684778-A1
Title: Bioactive fraction from extracts of Salicornia plant species, useful for treating tuberculosis
Inventors: RATHOD M R; SHETHIA B D; PANDYA J B; GHOSH P K; DODIA P J; SRIVASTAVA B S; SRIVASTAVA R; SRIVASTAVA A; GUPTA C M; CHATURVEDI V. |
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US Patent No. 7442393
Title: Herbal extract of Salicornia species process of preparation thereof, use thereof against tuberculosis.
Inventors: Rathod MK, Shethia BD, Pandya JB, Ghosh PK, Dodia J, Srivastava BS, Srivastava R, Srivastava A, Chaturvedi V. |
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Eur Patent No. 1684778
A novel use of herbal extracts of Salicornia species active against tuberculosis and process for the preparation thereof.
Inventors : Rathod MK, Shethia BD, Pandya JB, Ghosh PK, Dodia J, Srivastava BS, Srivastava R, Srivastava A, Chaturvedi V. |
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Australian Patent No. 2003259548
Title: Herbal extracts of Salicornia species process and preparation thereof , use thereof against tuberculosis.
Inventors: Rathod MK, Shethia BD, Pandya JB, Ghosh PK, Dodia J, Srivastava BS, Srivastava R, Srivastava A, Chaturvedi V. |
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Patent No. AP/P/2006/003567
Title: Herbal extracts of Salicornia species, process of preparation thereof, use thereof against tuberculosis.
Inventors: M R rathod, BD Shethia, JB Pandey, PK Ghosh, PJ Dodia, B S Srivastava, R Srivastava, A Srivastava, CM gupta and V Chaturvedi. |
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Patent No. AP/P/2006/003567
Title: Herbal extracts of Salicornia species, process of preparation thereof, use thereof against tuberculosis.
Inventors: M R rathod, BD Shethia, JB Pandey, PK Ghosh, PJ Dodia, B S Srivastava, R Srivastava, A Srivastava, CM gupta and V Chaturvedi.
The patent has been granted by the following five countries,
Kenya, Sudan, Tanzania, Zambia and Zimbawe |
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Patent No. 2006/02576
Title: A novel use of herbal extracts of Salicornia species active against tuberculosis and process for the preparation thereof.
Inventors: MR Rathod, BD Shethia, J BPandya, PK Ghosh, PJ Dodia, BS Srivastava, R Srivastava, A Srivastava, Chittar CM Gupta & V Chaturvedi. |
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Patent No. AP2250
Title: Herbal extracts of salicornia species, process of preparation thereof, use thereof against tuberculosis.
Inventors: MR Rathod, BD Shethia, J BPandya, PK Ghosh, PJ Dodia, BS Srivastava, R Srivastava, A Srivastava, Chittar CM Gupta & V Chaturvedi. |
Indian Patents |
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Patent Number: IN200401529-I1
Title: Novel combinatorial library of 3-substituted amino-3-glycosylated propionamides useful as antifungal and antibacterial agents.
Inventors: TRIPATHI R P; SHUKLA P K; SINHA S; SRIVASTAVA R; SRIVASTAVA K K; CHATURVEDI V; SRIVASTAVA A; SRIVASTAVA B S. |
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Patent Number: IN200402307-I1
Title: Novel N, N-di-glycosylated di-aminoalcohol useful in chemotherapy of tubercular infections.
Inventors: TRIPATHI R P; TIWARI V K; TEWARI N; SRIVASTVA R; SRIVASTAVA A; CHATURVEDI V; SRIVASTAVA K K; SINHA S; SRIVASTAVA B S. |
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Patent Number: IN200401098-I1
Title: Process for preparation of novel 1,3,5-thiazidine-2-thione.
Inventors: TRIPATHI R P; KATIYAR D; SRIVASTAVA R; SRIVASTAVA A; CHATURVEDI V; SRIVASTAVA B S. |
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Patent Number: IN200400716-I1
Title: Novel combinatorial library of 3-substituted amino-3-glycosylated propanoates useful as antifungal and antibacterial agents.
Inventors: TRIPATHI R P; KUNDU B; SHUKLA P K; SINHA S; SRIVASTAVA R; SRIVASTAVA K K; CHATURVEDI V; SRIVASTAVA A; SRIVASTAVA B S. |
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Patent Number: IN200400715-I1
Title: Novel combinatorial library of N1-glycosylated and N2-substituted ureas and thioureas.
Inventors: TRIPATHI R P; TIWARI V K; MISRA R C; SRIVASTAVA R; SRIVASTAVA K K; SRIVASTAVA A; CHATURVEDI V; SINHA S; SRIVASTAVA B S. |
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Patent Number: IN200401609-I1
Title: Process for preparation of galacto pyranosylated amino alcohols.
Inventors: TRIPATHI R P; TEWARI N; MISHRA R C; SRIVASTAVA R; SINHA S; SRIVASTAVA A; CHATURVEDI V; SRIVASTAVA B S. |
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Patent Number: IN200401100-I1
Title: Novel 1,3,5-thiazidine-2-thione for treating tuberculosis
Inventors: TRIPATHI R P; KATIYAR D; SRIVASTAVA R; SRIVASTAVA A; CHATURVEDI V; SRIVASTAVA B S. |
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Patent Number: IN200200999-I1
Title: Novel N',N''-diglycosylated diaminoalcohol combinatorial library useful in chemotherapy of tubercular infections.
Inventors: TRIPATHI R P; TIWARJ V K; TEWARI N; SRIVASTVA R; SRIVASTAVA A; CHATURVEDI V; SINHA S; SRIVASTAVA B S. |
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Patent Number: IN200200998-I1
Title: Preparation of novel N',N''-diglycosylated diaminoalcohol useful in chemotherapy of tubercular infections.
Inventors: TRIPATHI R P; TIWARJ V K; TEWARI N; SRIVASTVA R; SRIVASTAVA A; CHATURVEDI V; SRIVASTAVA K K; SINHA S; SRIVASTAVA B S. |
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Patent Number: IN194984-B
Title: A process for the preparation of 3-substituted amino-3-glycosylated propanoates useful as antifungal and antibacterial agents.
Inventors: TRIPATHI R P; KUNDU B; SHUKLA P K; SINHA S; SRIVASTAVA R; SRIVASTAVA K K; CHATURVEDI V; SRIVASTAVA A; SRIVASTAVA B S |
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Patent Number 242121
Title: A novel combinatorial library of 3-substitutedamino-3-glycosylatedpropanates, useful as antifungal and antibacterial agents.
Inventors: Rama pati tripathi,,Bijoy Kundu, Praveen Kumar shukla,
Sudhir Sinha, Ranjana Srivastava, Kishore Kumar Srivastava, Vinita Chaturvedi, Anil Srivastava and Brahm Shankar Srivastava. |
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Patent Number 227532
Title: A novel use of herbal extracts of Salicornia species active against tuberculosis and process for the preparation thereof.
Inventors: Meena Rajnikanth Rathod, Bhupendra Dhanvantrai Shethia, Jayant Batukrai Pandya, Pushpito Kumar Ghosh, Prakash Jagjivanbhai Dodia, Brahm Shanker Srivastava, Ranjana Srivastava, Anil Srivastava, Chittar Mal Gupta & Vinita Chaturvedi. |
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Patent Number 199829
Title: A process for the preparation of novel N1,N,N-diglycosylated diaminoalcohols useful in chemotherapy of tubercular infections.
Inventors: Rama Pati tripathi, Vinod Kumar Tiwari, Neetu Tiwar, Ranjana Srivastava, Anil Kumar Srivastava, Vinita Chaturvedi, Kishore Kumar Srivastava, Sudhir Sinha and Brahm Shankar Srivastava. |
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