DR. W HAQ
 
...

Chief Scientist
Medicinal and Process Chemistry Division
Central Drug Research Institute
Sector-10, Jankipuram Extension
Lucknow 226031, UP, India

 
Phone No. +91-0522-2962672; PABX 4970
E- mail [email protected], [email protected]
Educational qualifications M.Sc., Ph.D

Date of Birth

01.07.1959

 
VISITS ABROAD
 

Visiting Scientist- Nov. 1991-Feb. 1992- Dept. of Chemistry, University of Arizona, USA

Visiting Scientist (DBT Overseas Fellow)- Jan. 1994-Feb.19 95 Dept. of Chemistry, University of Arizona, USA
Visiting scientist- August 22-26, 1995- Ferring Peptide Production AB, Malmo, Sweden
Visiting Investigator- June 2003-Nov. 2004- Beckman Research Institute, Duarte, CA, USA
 
CURRENT AREAS OF INTEREST
Design and synthesis of peptides and small organic molecules of therapeutic interest
SELECTED PUBLICATIONS
 

Thiazolidin-4-one and thiazinan-4-one derivatives analogous to rosiglitazone as potential antihyperglycemic and antidyslipidemic agents. Raza S, Srivastava SP, Srivastava DS, Srivastava AK, Haq W, Katti SB. Eur J Med Chem. 2013, 63:611-20.

Augmentation of antileishmanial efficacy of miltefosine in combination with tuftsin against experimental visceral leishmaniasis. Shakya N, Sane SA, Haq W, Gupta S. Parasitol Res. 2012, 111(2):563-70.

Synthesis and pharmacological evaluation of novel arginine analogs as potential inhibitors of acetylcholine-induced relaxation in rat thoracic aortic rings. Jain M, Barthwal MK, Haq W, Katti SB, Dikshit M. Chem Biol Drug Des. 2012, 79(4):459-69

Anti-stroke profile of thiazolidin-4-one derivatives in focal cerebral ischemia model in rat. Raghubir R, Verma R, Samuel SS, Raza S, Haq W, Katti SB. Chem Biol Drug Des. 2011, 78(3):445-53.

CpG oligodeoxynucleotide 2006 and miltefosine, a potential combination for treatment of experimental visceral leishmaniasis. Gupta S, Sane SA, Shakya N, Vishwakarma P, Haq W. Antimicrob Agents Chemother. 2011, 55(7):3461-4.

Derivatives of human beta-casein fragments (54-59) exhibit highly potent immunosuppressant activity. Puri A, Bhattacharya M, Tripathi LM, Haq W. Int Immunopharmacol. 2009, 9(9):1092-6.

Solomon VR, Haq W, Srivastava K, Puri SK, Katti SB. Synthesis and antimalarial activity of side chain modified 4-aminoquinoline derivatives. J Med Chem. 50, 394-8, 2007
Song GY, Gibson G, Haq W, Huang EC, Srivastava T, Hollstein M, Daftarian P, Wang Z, Diamond D, Ellenhorn JD. An MVA vaccine overcomes tolerance to human p53 in mice and humans. Cancer Immunol Immunother. 56, 1193-1205, 2007
Design, Synthesis and Antimalarial activity of a new class of Iron chelators. V. Raja Solomon, W. Haq, Sunil K. Puri, Kumkum Srivastava, S.B. Katti. Medicinal Chemistry, 2, 133-8, 2006
Gupta CM, Haq W. Tuftsin-bearing liposomes as antibiotic carriers in treatment of macrophage infections. Methods Enzymol. 391, 291-304, 2005
Daftarian P, Sharan R, Haq W, Ali S, Longmate J, Termini J, Diamond DJ.Novel conjugates of epitope fusion peptides with CpG-ODN display enhanced immunogenicity and HIV recognition. Vaccine. 2005 May 16;23(26):3453-68.
Immunosuppressant activity in human beta-casein fragment analogs. M. Bahattacharya, A. Puri, R. Sahai, W. Haq, L.M. Tripathi and V.M.L. Srivastava. Bioorganic Med. Chem. Lett. 8, 327-332, 1998.