Assay |
Model system |
Disease area |
Sample
quantity required |
Scientists involved |
Plasmodium falciparum
SYBR Green based assay |
In- vitro: whole cell assay |
Malaria |
15 mg |
Dr Kumkum Srivastava |
Plasmodium yoelii ( N-67) - Swiss mice
Plasmodium yoelii ( MDR) - Swiss mice |
In-vivo: Primary model for Blood Schizontocidal assay |
Malaria |
200 mg |
Dr Renu Tripathi |
Plasmodium yoelii ( N-67) - Anopheles stephensi - Swiss mice |
In-vitro: Primary model for tissue Schizontocidal assay |
Malaria |
200 mg |
Dr Renu Tripathi |
Plasmodium cynomolgi - Rhesus monkey |
In-vivo: Secondary model for blood Schizontocidal /
Anti-relapse assay |
Malaria |
3.0 gm |
Dr Renu Tripathi |
Leishmania donovani -Macrophase- Amastigote Luciferase based assay |
In vitro: whole cell assay |
Leishmaniasis |
15 mg |
Dr Neena Goyal |
Leishmania donovani- Macrophase- Amastigote GFP based assay |
In vitro: whole cell assay |
Leishmaniasis |
15 mg |
Dr Anuradha Dube |
Leishmania donovani Golden hamster chronic model |
In vivo: assay |
Leishmaniasis |
300 mg |
Dr Neena Goyal
Dr Anuradha Dube |
Brugia malayi- MTT and motility assay |
In vitro: whole parasite assay |
Filariasis |
20 mg |
Dr S Bhattacharya
|
Brugia malayi- Adult transplanted in JIRD |
In vivo: Primary assay |
Filariasis |
300 mg |
Dr S Bhattacharya
|
L3 induced Brugia malayi- Mastomys |
In vivo: Secondary model |
Filariasis |
500 mg |
Dr S Bhattacharya
|
