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  COMBINATORIAL CHEMISTRY
 
Polymer supported synthesis of combinatorial libraries of trageted molecules both in parallel format as well as in mixture based format.
 Major Equipment Acquired
   
Multiple organic synthesizer
High throughput HPLC with LC/MS
Single based on FTIR microscope
Freeze dryer
Single bead FTIR microscope
 
Highthroughput HPLC-MS
 Special Features of Equipments
   
Fully automated synthesizers
On line hearing cooling cleavage
Several robotic pipettes for fast delivery of solvents/reagents
Performs chemistry at 0-6 atmosphere
Purification of 200 samples in a day
Purification of batch size1-to 50 mg
Both UV/MS (twin units) triggered purification
Parallel purification of two samples at a time
Monitoring of reactions on solid phase
 
Staff employee and Personnel trained
Several staff members have received training both in U.S.A. and Europe in the area of combinational chemistry. At the moment a strong contingent of six dedicated scientists and fourteen Ph.D. students are practicing combinational chemistry.
 
Facility in charge : Dr. B.Kundu, Division of Medicinal Chemistry, E-mail: bijoy_kundu[at]yahoo dot com
 
 
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