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  HIGH THROUGHPUT SCREENING (HTS) SYSTEM
 
This facility has been established for in-vitro biological screening of chemical libraries using a battery of target/ cell based assays.
 Objectives
   
Adoption of screening models for HTS
In vitro screening of chemical libraries and natural products in target (enzyme/receptor) cell based assay
Identification of new structural prototypes for drug development
Research into development of new target-based screens
High throughtput screening system
 
Close-up view of the robot
 Major Equipment Acquired
Medium Throughput Screening System
   
 Special Features of Equipment
Robotic liquid handler
Incubators with robotic access
On-line bar code reader, plate shaker, plate washer, plate filtration
Plate readers Radioactivity, luminescence, absorbance and fluorescence
Sterile operations for cell-based assays
 
Collaborative programs with pharmaceutical companies
Two collaborative programs with major pharmaceutical industries in the area of High throughput screening and Combichem have been initiated.
 
Facility in charge : Dr. S. Sinha, TDSD Unit, Division of Biochemistry, E-mail: [email protected]
 
 
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